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pro vyhledávání: '"Heidi, Segal"'
Autor:
Joanna C. Evans, Heidi Segal
Publikováno v:
Journal of Antimicrobial Chemotherapy. 65:897-900
Objectives: The use of rapid molecular assays for the detection of resistance to second-line drugs would significantly decrease the time delay in diagnosing drug-resistant tuberculosis (TB) that is associated with conventional phenotypic drug suscept
Autor:
Heidi Segal, B.Gay Elisha
Publikováno v:
FEMS Microbiology Letters. 153:321-326
Transformation studies showed that an aminoglycoside resistance gene, aadB, is carried on a 6.0-kb plasmid (pRAY) in a clinical isolate of Acinetobacter (strain SUN). The gene was cloned and sequenced. An analysis of the DNA sequencing data showed th
Publikováno v:
FEMS Microbiology Letters. 243:425-429
An insertion sequence (IS(ABA-1)) was identified in Acinetobacter spp., but not in Enterobacteriacea and Pseudomonas aeruginosa. Numerous copies of the IS were identified in Acinetobacter strains containing the element. In one of the Acinetobacter ba
Autor:
Jean-Emmanuel Hugonnet, Jean-Paul Brouard, Lionnel Dubost, Michel Arthur, Nathalie Josseaume, Heidi Segal, Ana Arbeloa, Dominique Mengin-Lecreulx, Laurent Gutmann
Publikováno v:
Journal of Bacteriology. 186:1221-1228
Peptidoglycan polymerization complexes contain multimodular penicillin-binding proteins (PBP) of classes A and B that associate a conserved C-terminal transpeptidase module to an N-terminal glycosyltransferase or morphogenesis module, respectively. I
Publikováno v:
Plasmid. 49:169-178
Based on hybridization studies, 21/32 multi-resistant clinical isolates of Acinetobacter baumannii contain class 1 integrons. Amplification products were obtained from 20 of the hybridization-positive strains. A single dfrA7 cassette was identified i
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:2538-2541
As the site of insertion of the aadB gene cassette on pRAY, from a clinical isolate of Acinetobacter , is almost identical to the preferred site on integrons, the composite 59-base element (59-BE) associated with this cassette is potentially recombin
Publikováno v:
The Journal of antimicrobial chemotherapy. 63(1)
Molecular assays to detect drug resistance in Mycobacterium tuberculosis are more rapid than standard drug susceptibility testing. To evaluate the efficacy of such assays in this setting, the GenoType MTBDRplus assay (HAIN Lifescience) and multiplex
Shiga toxin-producing Escherichia coli (STEC) strains from cattle and diarrheic children in a pastoralist community in Uganda were investigated. The STEC strains belonged to a variety of different serogroups, and 70% of the strains were positive for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a0c5a945cd9f387c6c6ded288d830d
https://europepmc.org/articles/PMC2224257/
https://europepmc.org/articles/PMC2224257/
Autor:
Heidi Segal, Joanna C. Evans
Publikováno v:
Antimicrobial agents and chemotherapy. 51(10)
Carbapenems are frequently used to treat Pseudomonas aeruginosa; however, resistance to the carbapenems is emerging rapidly (9). Mutations or deletions in oprD (3, 2, 8) commonly result in lack of OprD expression, blocking the entry of imipenem into
Autor:
Heidi Segal, B. Gay Elisha
Publikováno v:
The Journal of antimicrobial chemotherapy. 56(3)
Sir, In2002,wesawtheemergenceofcarbapenemresistanceinclinical isolates of Acinetobacter baumannii isolated from patients at two local hospitals, Groote Schuur Hospital (GSH) and Tygerberg Hospital (TH), Western Cape, South Africa. The high levels of