Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Heidi, Olzscha"'
Autor:
Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, Ruchika Anand, Linda A. M. Kulka, David Meierhofer, Petar Glazar, Ivano Legnini, Narasimha Swamy Telugu, Tobias Hahn, Nancy Neuendorf, Duncan C. Miller, Annett Böddrich, Amin Polzin, Ertan Mayatepek, Sebastian Diecke, Heidi Olzscha, Janine Kirstein, Cristina Ugalde, Spyros Petrakis, Sidney Cambridge, Nikolaus Rajewsky, Ralf Kühn, Erich E. Wanker, Josef Priller, Jakob J. Metzger, Alessandro Prigione
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Expansion of the glutamine tract (poly-Q) in the protein huntingtin (HTT) causes the neurodegenerative disorder Huntington’s disease (HD). Emerging evidence suggests that mutant HTT (mHTT) disrupts brain development. To gain mechanistic in
Externí odkaz:
https://doaj.org/article/340c015abcae4c679391b04ea77b6a41
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/8ce65e61c7a4443393872f2b37d9d693
Autor:
Timo Längrich, Kaya Bork, Rüdiger Horstkorte, Veronika Weber, Britt Hofmann, Matt Fuszard, Heidi Olzscha
Publikováno v:
Proteomes, Vol 10, Iss 3, p 28 (2022)
Background: Propofol is a short-acting anesthetic, which is often used for induction and maintenance of general anesthesia, sedation for mechanically ventilated adults and procedural sedation. Several side effects of propofol are known and a substant
Externí odkaz:
https://doaj.org/article/7aa7ae012ee54799983b70b259c5f603
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Lysine acetylation is one of the major posttranslational modifications (PTM) in human cells and thus needs to be tightly regulated by the writers of this process, the histone acetyl transferases (HAT), and the erasers, the histone deacetylases (HDAC)
Externí odkaz:
https://doaj.org/article/8bb7b51027964289940edbac91fc39c0
Autor:
Nicholas B. La Thangue, Benedikt Kessler, Reuben M. Tooze, Susan Fotheringham, Matthew A. Care, Marie-Laetitia Thezenas, Heidi Olzscha, Mina Bekheet, Semira Sheikh, Maria New
Histone deacetylase (HDAC) inhibitors have proven useful therapeutic agents for certain hematologic cancers. However, HDAC inhibition causes diverse cellular outcomes, and identification of cancer-relevant pathways within these outcomes remains unres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76925f9946b9169a64b41fae678c7929
https://doi.org/10.1158/0008-5472.c.6508427
https://doi.org/10.1158/0008-5472.c.6508427
Autor:
Nicholas B. La Thangue, Benedikt Kessler, Reuben M. Tooze, Susan Fotheringham, Matthew A. Care, Marie-Laetitia Thezenas, Heidi Olzscha, Mina Bekheet, Semira Sheikh, Maria New
High-resolution heat map of top gene signatures and GO terms enriched for top MYD88 correlated genes in ABC DLBCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c56ca3f51f228aa4a4d340d0c4407a
https://doi.org/10.1158/0008-5472.22412369.v1
https://doi.org/10.1158/0008-5472.22412369.v1
Autor:
Nicholas B. La Thangue, Benedikt Kessler, Reuben M. Tooze, Susan Fotheringham, Matthew A. Care, Marie-Laetitia Thezenas, Heidi Olzscha, Mina Bekheet, Semira Sheikh, Maria New
MYD88 expression and IL-6 sensitises cells to HDAC inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e91d2754379066776782f919830043
https://doi.org/10.1158/0008-5472.22412387
https://doi.org/10.1158/0008-5472.22412387
Autor:
Nicholas B. La Thangue, Benedikt Kessler, Reuben M. Tooze, Susan Fotheringham, Matthew A. Care, Marie-Laetitia Thezenas, Heidi Olzscha, Mina Bekheet, Semira Sheikh, Maria New
Supplemental figures 1-5 legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051583f1c3cd3116b260afa0a6eda517
https://doi.org/10.1158/0008-5472.22412366
https://doi.org/10.1158/0008-5472.22412366
Autor:
Nicholas B. La Thangue, Benedikt Kessler, Reuben M. Tooze, Susan Fotheringham, Matthew A. Care, Marie-Laetitia Thezenas, Heidi Olzscha, Mina Bekheet, Semira Sheikh, Maria New
MYD88 expression coincides with an acetylation signature at ABC subgroup-specific GO gene clusters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7081aae0d5614af91dbc30f9aac775
https://doi.org/10.1158/0008-5472.22412375.v1
https://doi.org/10.1158/0008-5472.22412375.v1
Autor:
Nicholas B. La Thangue, Benedikt Kessler, Reuben M. Tooze, Susan Fotheringham, Matthew A. Care, Marie-Laetitia Thezenas, Heidi Olzscha, Mina Bekheet, Semira Sheikh, Maria New
High levels of MYD88 are apparent in tissue microarray biopsies from patients with DLBCL, but not prostate and colorectal cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a60c9d12ce357a5cefe3eada13d09a5
https://doi.org/10.1158/0008-5472.22412378
https://doi.org/10.1158/0008-5472.22412378