Výsledky vyhledávání - "Heidi, Kemiläinen"

The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer

Autor: Kaisa Huhtinen, Annika Auranen, Leena Strauss, Olli Carpén, Heidi Kemiläinen, Matti Poutanen

Publikováno v: Oncology. 94(4):233-242

Objective: The aim of this study was to characterize the expression of hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12), an enzyme involved in the synthesis of arachidonic acid (AA), in ovarian cancer, and to study its coexpression with its ups

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd391f39ac6927ac5d0f7721c8fa617
http://juuli.fi/Record/0330040118

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The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of Fertility

Autor: Pauliina Damdimopoulou, Teemu D. Laajala, Outi Hovatta, Jerzy Adamski, Anastasios E. Damdimopoulos, Leena Strauss, Juha Kere, Heidi Kemiläinen, Marion Adam, Henrik Ryberg, Matti Poutanen, Claes Ohlsson, Jenni Mäki-Jouppila, Tero Aittokallio

Publikováno v: Endocrinology 157, 3719-3730 (2016)

The hydroxysteroid (17beta) dehydrogenase (HSD17B)12 gene belongs to the hydroxysteroid (17β) dehydrogenase superfamily, and it has been implicated in the conversion of estrone to estradiol as well as in the synthesis of arachidonic acid (AA). AA is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1bd1de7d9adb97216f8446477ea113
https://doi.org/10.1210/en.2016-1252

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Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1 and AFB-N7-guanine) in young Chinese males

Autor: Huilian Zhu, Jing Ma, Hani El-Nezami, Wenhua Ling, Hannu Mykkänen, Risto O. Juvonen, Otto Mykkänen, Nektaria Polychronaki, Seppo Salminen, Heidi Kemiläinen, Eeva Salminen

Publikováno v: International Journal of Cancer. 115:879-884

Our study was designed to assess the fecal and urinary excretion of 3 aflatoxin B1 (AFB1) metabolites, aflatoxins M1 (AFM1) and Q1 (AFQ1) and aflatoxin B1-N7-guanine (AFB-N7-guanine) that are produced by the predominant forms of cytochrome P450 enzym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9dcb239805d857062019890d0a396e
https://doi.org/10.1002/ijc.20951

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[Results of percutaneous coronary angioplasty and effect on the patients' condition and symptoms]

Autor: Heidi, Kemiläinen, Johanna, Kaulamo, Outi, Heikkinen, Heikki, Miettinen, Johanna, Kuusisto

Publikováno v: Duodecim; laaketieteellinen aikakauskirja. 130(1)

More than 10,000 percutaneous coronary angioplasties are performed in Finland annually. We examined in a three-year follow-up the results of percutaneous coronary angioplasty performed for 875 patients at the Kuopio University Hospital. Procedural an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8893d3ad4432e40e8463d3f0cc7a7f1
https://pubmed.ncbi.nlm.nih.gov/24547626

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Decrease in intracellular concentration causes the shift in Km value of efflux pump substrates

Autor: Timo Korjamo, Heidi Kemiläinen, Jukka Mönkkönen, Aki T. Heikkinen

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 35(9)

Passive permeability and active efflux are parallel processes in transcellular flux. Therefore, the observed kinetics of a transporter substrate depends on both of these factors. The transporter expression has been shown to affect both the apparent K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e1400cb15ba61ec69bf175d6ad1056
https://pubmed.ncbi.nlm.nih.gov/17548462

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