Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Heidemarie Huber"'
Autor:
Katharina Staufer, Heidemarie Huber, Jasmin Zessner-Spitzenberg, Rudolf Stauber, Armin Finkenstedt, Heike Bantel, Thomas S. Weiss, Markus Huber, Patrick Starlinger, Thomas Gruenberger, Thomas Reiberger, Susanne Sebens, Gail McIntyre, Ray Tabibiazar, Amato Giaccia, Heinz Zoller, Michael Trauner, Wolfgang Mikulits
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract The expression of the receptor tyrosine kinase Axl and its cleavage product soluble Axl (sAxl) is increased in liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). In this multicenter study, we evaluated the diagnostic value of Gas
Externí odkaz:
https://doaj.org/article/6ec11fb752674d009f3b4dccfb87f223
Autor:
Kristina Breitenecker, Viola Hedrich, Franziska Pupp, Doris Chen, Eva Řezníčková, Gregor Ortmayr, Heidemarie Huber, Gerhard Weber, Lorenz Balcar, Matthias Pinter, Wolfgang Mikulits
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionHepatocellular carcinoma (HCC) patients at advanced stages receive immunotherapy or treatment with tyrosine kinase inhibitors (TKIs) such as Sorafenib (Sora) or Lenvatinib in frontline as well as Regorafenib (Rego) or Cabozantinib in seco
Externí odkaz:
https://doaj.org/article/c7d00e5156d647469e16c383d6cf5ad0
Autor:
Gregor Ortmayr, Laura Brunnthaler, David Pereyra, Heidemarie Huber, Jonas Santol, Benedikt Rumpf, Sina Najarnia, Rory Smoot, Daphni Ammon, Thomas Sorz, Fabian Fritsch, Michael Schodl, Astrid Voill‐Glaninger, Barbara Weitmayr, Manuela Födinger, Martin Klimpfinger, Thomas Gruenberger, Alice Assinger, Wolfgang Mikulits, Patrick Starlinger
Publikováno v:
Hepatology Communications, Vol 6, Iss 3, Pp 576-592 (2022)
AXL and its corresponding ligand growth arrest–specific 6 (GAS‐6) are critically involved in hepatic immunomodulation and regenerative processes. Pleiotropic inhibitory effects on innate inflammatory responses might essentially involve the shift
Externí odkaz:
https://doaj.org/article/bea4b03e9afb4710a94c45a0718b6377
Autor:
Patricia Sancho, Jèssica Mainez, Eva Crosas-Molist, César Roncero, Conrado M Fernández-Rodriguez, Fernando Pinedo, Heidemarie Huber, Robert Eferl, Wolfgang Mikulits, Isabel Fabregat
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45285 (2012)
A role for the NADPH oxidases NOX1 and NOX2 in liver fibrosis has been proposed, but the implication of NOX4 is poorly understood yet. The aim of this work was to study the functional role of NOX4 in different cell populations implicated in liver fib
Externí odkaz:
https://doaj.org/article/75617722b61f41f39952517e7d2fb884
Autor:
Viola Hedrich, Kristina Breitenecker, Gregor Ortmayr, Franziska Pupp, Heidemarie Huber, Doris Chen, Sarthak Sahoo, Mohit Kumar Jolly, Wolfgang Mikulits
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2415
(1) Background: Activation of the receptor tyrosine kinase Axl by Gas6 fosters oncogenic effects in hepatocellular carcinoma (HCC), associating with increased mortality of patients. The impact of Gas6/Axl signaling on the induction of individual targ
Publikováno v:
Clinical Cancer Research. 28:PO019-PO019
The receptor tyrosine kinase Axl, binding to its ligand Gas6, fosters oncogenic effects during the progression of hepatocellular carcinoma (HCC) which is accompanied by increased mortality of patients. The specific role of Gas6/Axl signaling in neopl
Autor:
Gregor Ortmayr, Laura Brunnthaler, David Pereyra, Heidemarie Huber, Jonas Santol, Benedikt Rumpf, Sina Najarnia, Rory Smoot, Daphni Ammon, Thomas Sorz, Fabian Fritsch, Michael Schodl, Astrid Voill‐Glaninger, Barbara Weitmayr, Manuela Födinger, Martin Klimpfinger, Thomas Gruenberger, Alice Assinger, Wolfgang Mikulits, Patrick Starlinger
Publikováno v:
Hepatology communications. 6(3)
AXL and its corresponding ligand growth arrest-specific 6 (GAS-6) are critically involved in hepatic immunomodulation and regenerative processes. Pleiotropic inhibitory effects on innate inflammatory responses might essentially involve the shift of m
Autor:
Katharina Staufer, Heidemarie Huber, Jasmin Zessner-Spitzenberg, Rudolf E. Stauber, Armin Finkenstedt, Heike Bantel, Thomas Weiss, Markus Huber, Patrick Starlinger, Thomas Grünberger, Thomas Reiberger, Susanne Sebens, Gail McIntyre, Ray Tabibiazar, Amato Giaccia, Heinz Zoller, Michael Trauner, Wolfgang Mikulits
Publikováno v:
Journal of Hepatology. 77:S470
Autor:
L. Brunnthaler, W. Mikultis, Patrick Starlinger, David Pereyra, G. Ortmayr, Thomas Gruenberger, Heidemarie Huber, A. Assinger
Publikováno v:
HPB. 23:S655
Autor:
Wolfgang Mikulits, Christian Müller, Mirko Dengler, Peter Rauch, Heidemarie Huber, Angela Zellmer
Publikováno v:
ASSAY and Drug Development Technologies. 14:543-550
Levels of soluble Axl (sAxl) are routinely assessed in human sera by sandwich enzyme-linked immunosorbent assay (ELISA). Although sAxl values are suggested to diagnose different types of disorders, no uniform ELISA method is available, allowing the r