Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Heide Siggelkow"'
Autor:
Julia Spiekermann, Jakob Höppner, Eliena Ibnukhsein, Kathrin Sinningen, Beatrice Hanusch, Cordula Kiewert, Heide Siggelkow, Corinna Grasemann
Publikováno v:
Molecular and Cellular Pediatrics, Vol 11, Iss 1, Pp 1-9 (2024)
Abstract Background In adults with Klinefelter syndrome (KS), impaired bone health with reduced bone mineral density (BMD) has been described even in the presence of testosterone replacement therapy. The aim of the present study was to characterize b
Externí odkaz:
https://doaj.org/article/d5ac7849c7fd4d9e9cd932f84c29b189
Autor:
Julia Spiekermann, Kathrin Sinningen, Beatrice Hanusch, Michaela Kleber, Michael M. Schündeln, Cordula Kiewert, Heide Siggelkow, Jakob Höppner, Corinna Grasemann
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundKlinefelter syndrome (KS) may be associated with a wide spectrum of phenotypic changes including endocrine, metabolic, cognitive, psychiatric and cardiorespiratory pathologies in adults. However, in adolescence the clinical phenotype of KS
Externí odkaz:
https://doaj.org/article/d17fe41a15864d3baf0992741aaaf302
Autor:
Angelique Kragl, Janosch Schoon, Ana Tzvetkova, Christoph Wenzel, Martina Blaschke, Wolfgang Böcker, Heide Siggelkow, Mladen V. Tzvetkov
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Exogenous glucocorticoids increase the risk for osteoporosis, but the role of endogenous glucocorticoids remains elusive. Here, we describe the generation and validation of a loss- and a gain-of-function model of the cortisol producing enzyme 11β-HS
Externí odkaz:
https://doaj.org/article/852deb572432487f84929e57f03d2a56
Autor:
Bettina Stamm, Martina Blaschke, Lara Wilken, Deborah Wilde, Christina Heppner, Andreas Leha, Christoph Herrmann‐Lingen, Heide Siggelkow
Publikováno v:
JBMR Plus, Vol 6, Iss 2, Pp n/a-n/a (2022)
ABSTRACT Quality of life (QoL) is impaired in patients with chronic hypoparathyroidism (HypoPT). With a recently developed specific patient questionnaire, the 28‐item Hypoparathyroid Patient Questionnaire (HPQ 28), we were able to demonstrate an ef
Externí odkaz:
https://doaj.org/article/040572fab9534439a143e16a54350ce2
Deficient knowledge in adult Turner syndrome care as an incentive to found Turner centers in Germany
Autor:
Elin Kahlert, Martina Blaschke, Knut Brockmann, Clemens Freiberg, Onno E Janssen, Nikolaus Stahnke, Domenika Strik, Martin Merkel, Alexander Mann, Klaus-Peter Liesenkötter, Heide Siggelkow
Publikováno v:
Endocrine Connections, Vol 8, Iss 11, Pp 1483-1492 (2019)
Objective: Turner syndrome (TS) is characterized by the complete or partial loss of the second sex chromosome and associated with a wide range of clinical manifestations. We aimed to assess the medical care of adult patients with TS in Germany. Desig
Externí odkaz:
https://doaj.org/article/48c85166dcc94dfb82113083b0e97e90
Autor:
Christof Wilke, Martina Blaschke, Annette Lamersdorf, Christina Heppner, Michael Metz, Hans-Peter Horny, Undine Lippert, Heide Siggelkow
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101023- (2021)
Externí odkaz:
https://doaj.org/article/9f24aa91221c4cba8862caab021aec67
Autor:
Deborah Wilde, Lara Wilken, Bettina Stamm, Christina Heppner, Andreas Leha, Martina Blaschke, Christoph Herrmann‐Lingen, Heide Siggelkow
Publikováno v:
JBMR Plus, Vol 4, Iss 7, Pp n/a-n/a (2020)
ABSTRACT In hypoparathyroidism (HypoPT), patients suffer severely from reduced quality of life. The complexity of HypoPT demands a disease‐specific control instrument to characterize symptom load. We employed a newly developed disease‐specific Hy
Externí odkaz:
https://doaj.org/article/1431589fdc2d4433ad8ada96cbf051c2
Autor:
Deborah Wilde, Lara Wilken, Bettina Stamm, Martina Blaschke, Christina Heppner, Mira‐Lynn Chavanon, Andreas Leha, Christoph Herrmann‐Lingen, Heide Siggelkow
Publikováno v:
JBMR Plus, Vol 4, Iss 1, Pp n/a-n/a (2020)
ABSTRACT Hypoparathyroidism patients suffer a variety of complaints often leading to reduced quality of life. Currently, no specific standard instrument exists to measure corresponding disease manifestations. We therefore aimed to develop a disease
Externí odkaz:
https://doaj.org/article/d1fcf95d6af14224beae033eaf1e165b
Autor:
Erika Baum, Bernhard Rintelen, Heide Siggelkow, Klaus Engelke, Claus-C. Glüer, Friederike Thomasius
Publikováno v:
Osteologie. 32:92-96
Zusammenfassung Ziel Im Rahmen der Überarbeitung der 2017er Leitlinie Prophylaxe, Diagnostik und Therapie der Osteoporose bei postmenopausalen Frauen und bei Männern für den Deutschsprachigen Raum sollte das Risiko für osteoporosetypische Fraktur
Autor:
Aliya A. Khan, Gordon Guyatt, Dalal S. Ali, John P. Bilezikian, Michael T. Collins, Karel Dandurand, Michael Mannstadt, Deborah Murphy, Iman M'Hiri, Mishaela R. Rubin, Robert Sanders, Muhammad Shrayyef, Heide Siggelkow, Gaia Tabacco, Yu‐Kwang Donovan Tay, Stan Van Uum, Tamara Vokes, Karen K. Winer, Liang Yao, Lars Rejnmark
Publikováno v:
Khan, A A, Guyatt, G, Ali, D S, Bilezikian, J P, Collins, M T, Dandurand, K, Mannstadt, M, Murphy, D, M'Hiri, I, Rubin, M R, Sanders, R, Shrayyef, M, Siggelkow, H, Tabacco, G, Tay, Y K D, Van Uum, S, Vokes, T, Winer, K K, Yao, L & Rejnmark, L 2022, ' Management of Hypoparathyroidism ', Journal of Bone and Mineral Research, vol. 37, no. 12, pp. 2663-2677 . https://doi.org/10.1002/jbmr.4716
Hypoparathyroidism (HypoPT) is a rare disorder characterized by hypocalcemia in the presence of a low or inappropriately normal parathyroid hormone level. HypoPT is most commonly seen after neck surgery, which accounts for approximately 75% of cases,