Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Heide Niederleithner"'
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Akademický článek
The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells.
Autor: Martina Hoeth, Heide Niederleithner, Renate Hofer-Warbinek, Martin Bilban, Herbert Mayer, Ulrike Resch, Christof Lemberger, Oswald Wagner, Erhard Hofer, Peter Petzelbauer, Rainer de Martin
Publikováno v: PLoS ONE, Vol 7, Iss 1, p e30982 (2012)
Mutations in the transcription factor SOX18 are responsible for specific cardiovascular defects in humans and mice. In order to gain insight into the molecular basis of its action, we identified target genes of SOX18 and analyzed one, MMP7, in detail
Externí odkaz: https://doaj.org/article/0a369d21d1c04c6cbee6df1bb36df034
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2
Autocrine VEGF Signaling Synergizes with EGFR in Tumor Cells to Promote Epithelial Cancer Development
Autor: Heide Niederleithner, Maria Sibilia, Napoleone Ferrara, Beate M. Lichtenberger, Poi Kiang Tan, Peter Petzelbauer
Publikováno v: Cell. 140:268-279
SummaryIt is established that tumor cell-derived VEGF acts on endothelial cells to promote angiogenesis and tumor growth. Here, we demonstrate that in K5-SOS-dependent mouse skin tumors, autocrine VEGF is required for tumor cell proliferation in a ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03f7e49c67bed56faea1bdfec32bfed
https://doi.org/10.1016/j.cell.2009.12.046
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3
A Previously Unknown Dermal Blood Vessel Phenotype in Skin Inflammation
Autor: Dontscho Kerjaschki, Marion Gröger, Heide Niederleithner, Peter Petzelbauer
Publikováno v: Journal of Investigative Dermatology. 127(12):2893-2900
Podoplanin and lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1) are considered as lineage markers for lymphatic vessel (LV) endothelial cells (LECs). We have recently shown that IL-3 induces de novo expression of these genes in cultured
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dd72b35b4032dbcfb60173dc0e307d
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4
Combination of dacarbazine and dimethylfumarate efficiently reduces melanoma lymph node metastasis
Autor: Teresa Valero, Hubert Pehamberger, Heide Niederleithner, Peter Petzelbauer, Robert Loewe, Silvia Steele, Karin Neumüller, Andreas Bracher
Publikováno v: The Journal of investigative dermatology. 130(4)
Dimethylfumarate (DMF) has been shown to reduce melanoma growth and metastasis in animal models. We addressed the question of whether DMF is as effective in its antitumor activity as the US Food and Drug Administration–approved alkylating agent dac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93149da89c75859cd1b6e634e765dd04
https://pubmed.ncbi.nlm.nih.gov/19940857
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7
The Transcription Factor SOX18 Regulates the Expression of Matrix Metalloproteinase 7 and Guidance Molecules in Human Endothelial Cells
Autor: Oswald Wagner, Martin Bilban, Erhard Hofer, Christof E. Lemberger, Ulrike Resch, Rainer de Martin, Renate Hofer-Warbinek, Heide Niederleithner, Peter Petzelbauer, Martina Hoeth, Herbert Mayer
Publikováno v: PLoS ONE, Vol 7, Iss 1, p e30982 (2012)
PLoS ONE
Background Mutations in the transcription factor SOX18 are responsible for specific cardiovascular defects in humans and mice. In order to gain insight into the molecular basis of its action, we identified target genes of SOX18 and analyzed one, MMP7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431f42871363ceaefb52eff7a2583f24
https://doi.org/10.1371/journal.pone.0030982
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9
Wnt1 Is Anti-Lymphangiogenic in a Melanoma Mouse Model
Autor: Heide Niederleithner, Martin Bilban, Magdalena Heinz, Stefanie Tauber, Walter Berger, Hubert Pehamberger, Peter Petzelbauer, Stefan Eugen Sonderegger, Robert Loewe, Martin Knöfler, Andreas Bracher
Publikováno v: Journal of Investigative Dermatology. (9):2235-2244
Wnt signals contribute to melanoma progression by boosting their proliferation and survival. Initially, we expected that activated Wnt signaling also improves their proficiency to recruit blood and lymph vessels. To assess this, we added cell culture
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6308776cd5f770b28cfaeed22d0b418c
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