Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Heide L Ford"'
Autor:
Lingdi Zhang, Hengbo Zhou, Xueni Li, Rebecca L Vartuli, Michael Rowse, Yongna Xing, Pratyaydipta Rudra, Debashis Ghosh, Rui Zhao, Heide L Ford
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Eya proteins are characterised by phosphatase activity associated with both the evolutionary conserved region and the less conserved N-terminal domain (NTD). Here the authors show that NTD mediates the interaction with PP2A and regulates c-Myc phosph
Externí odkaz:
https://doaj.org/article/e85d17f3da1b488cb955698e3352b45c
Autor:
Christina Menke, Tatiana Goncharov, Lubna Qamar, Christopher Korch, Heide L Ford, Kian Behbakht, Andrew Thorburn
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14527 (2011)
Signaling by Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) and Fas ligand (FasL) has been proposed to contribute to the chemosensitivity of tumor cells treated with various other anti-cancer agents. However, the importance of these
Externí odkaz:
https://doaj.org/article/982b9d87e9544197aed07addf6142ddf
Autor:
Connor J. Hughes, Kaiah M. Fields, Etienne P. Danis, Jessica Y. Hsu, Deepika Neelakantan, Melanie Y. Vincent, Annika L. Gustafson, Michael J. Oliphant, Varsha Sreekanth, Vadym Zaberezhnyy, James C. Costello, Paul Jedlicka, Heide L. Ford
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Ewing sarcoma (ES), which is characterized by the presence of oncogenic fusion proteins such as EWS/FLI1, is an aggressive pediatric malignancy with a high rate of early dissemination and poor outcome after distant spread. Here we demonstrat
Externí odkaz:
https://doaj.org/article/ee87edcfee7141c997bb753eb3383753
Autor:
Cory Wilson, Tinne C.J. Mertens, Pooja Shivshankar, Weizen Bi, Scott D. Collum, Nancy Wareing, Junsuk Ko, Tingting Weng, Ram P. Naikawadi, Paul J. Wolters, Pascal Maire, Soma S.K. Jyothula, Rajarajan A. Thandavarayan, Dewei Ren, Nathan D. Elrod, Eric J. Wagner, Howard J. Huang, Burton F. Dickey, Heide L. Ford, Harry Karmouty-Quintana
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Idiopathic pulmonary fibrosis (IPF) is a fatal disease with limited treatment options. The role of the developmental transcription factor Sine oculis homeobox homolog 1 (SIX1) in the pathophysiology of lung fibrosis is not known. IPF lung tissue samp
Externí odkaz:
https://doaj.org/article/0b6befeecf974b68b90fc8fc86c89505
Autor:
Heide L. Ford, Andrew Thorburn, Aik-Choon Tan, Christopher C. Porter, Susan Fosmire, Jihye Kim, Taylor J. Hotz, Kian Behbakht, Christina G. Towers, Lina Y. Dimberg
Supplemental Figure 1: TRAIL-resistant BJAB-LexR cells are not resistant to other drugs. Supplemental Figure 2: TRAIL-resistant MDA-MB-231 cells are not resistant to other drugs. Supplemental Figure 3: Knock-down of SLC26A2 does not affect sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e1b97154fb5f0d8708d3f90b8e4f07
https://doi.org/10.1158/1541-7786.22511439.v1
https://doi.org/10.1158/1541-7786.22511439.v1
Autor:
CongBao Kang, Heide L. Ford, Rui Zhao, Thomas H. Keller, Jeffrey Hill, Debashis Ghosh, Pratyaydipta Rudra, Juan Marugan, Samarjit Patnaik, Joma Joy, Alvin W. Hung, Grace Lin, Nithya Baburajendran, Yee Khoon Yeo, Elizabeth Yihui Ng, John Wee Liang Kuan, Anna E. Jansson, Melanie A. Blevins, Melanie Y. Vincent, Taylor Hotz, Lingdi Zhang, Hengbo Zhou, Jothi Anantharajan
Alphascreen monitoring of the Six1/Eya2 interaction demonstrates that compound 9987 has no effect on this interaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295b0e35587df3b1089c280380400082
https://doi.org/10.1158/1535-7163.22506058
https://doi.org/10.1158/1535-7163.22506058
Autor:
CongBao Kang, Heide L. Ford, Rui Zhao, Thomas H. Keller, Jeffrey Hill, Debashis Ghosh, Pratyaydipta Rudra, Juan Marugan, Samarjit Patnaik, Joma Joy, Alvin W. Hung, Grace Lin, Nithya Baburajendran, Yee Khoon Yeo, Elizabeth Yihui Ng, John Wee Liang Kuan, Anna E. Jansson, Melanie A. Blevins, Melanie Y. Vincent, Taylor Hotz, Lingdi Zhang, Hengbo Zhou, Jothi Anantharajan
Compound inhibition of different Eya proteins and Eya mutants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb179ac59f1826999b81687eb856683a
https://doi.org/10.1158/1535-7163.22506052.v1
https://doi.org/10.1158/1535-7163.22506052.v1
Autor:
Heide L. Ford, Andrew Thorburn, Aik-Choon Tan, Christopher C. Porter, Susan Fosmire, Jihye Kim, Taylor J. Hotz, Kian Behbakht, Christina G. Towers, Lina Y. Dimberg
Supplemental Table 1: Significantly enriched pathways from GIANT analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e94ece2694d134e9a48dc8473792a0
https://doi.org/10.1158/1541-7786.22511445
https://doi.org/10.1158/1541-7786.22511445
Autor:
CongBao Kang, Heide L. Ford, Rui Zhao, Thomas H. Keller, Jeffrey Hill, Debashis Ghosh, Pratyaydipta Rudra, Juan Marugan, Samarjit Patnaik, Joma Joy, Alvin W. Hung, Grace Lin, Nithya Baburajendran, Yee Khoon Yeo, Elizabeth Yihui Ng, John Wee Liang Kuan, Anna E. Jansson, Melanie A. Blevins, Melanie Y. Vincent, Taylor Hotz, Lingdi Zhang, Hengbo Zhou, Jothi Anantharajan
Eya2 and Six1 expression in different lung cancer cell lines, along with the effects of Eya2 and Eya2 D274N on protein localization and EMT markers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47800cc22baa5293d7bd53e419821b02
https://doi.org/10.1158/1535-7163.22506049.v1
https://doi.org/10.1158/1535-7163.22506049.v1
Autor:
CongBao Kang, Heide L. Ford, Rui Zhao, Thomas H. Keller, Jeffrey Hill, Debashis Ghosh, Pratyaydipta Rudra, Juan Marugan, Samarjit Patnaik, Joma Joy, Alvin W. Hung, Grace Lin, Nithya Baburajendran, Yee Khoon Yeo, Elizabeth Yihui Ng, John Wee Liang Kuan, Anna E. Jansson, Melanie A. Blevins, Melanie Y. Vincent, Taylor Hotz, Lingdi Zhang, Hengbo Zhou, Jothi Anantharajan
Eya2 binding to Six1 is critical for its ability to mediate numerous phenotypes in Calu-6 lung cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cc5555fa01d8ea3ac6c4052fea03e3
https://doi.org/10.1158/1535-7163.22506046
https://doi.org/10.1158/1535-7163.22506046