Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Heide, Muckenfuss"'
Publikováno v:
Vaccine. 36:2364-2370
Introduction The governmental quality control of human vaccines is a long established tradition in many European countries. In Germany, vaccines have been controlled by a governmental agency since 1935. In the beginning, vaccine production and contro
Autor:
Heide Muckenfuß
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 60:1208-1213
Die Zahl der Arzneimittelfalschungen auf dem deutschen Markt ist in den letzten Jahren deutlich angestiegen. Vor allem gestohlene Arzneimittel, die zu den Arzneimittelfalschungen zahlen, werden zunehmend uber den Parallelhandel in die legale Handelsk
Autor:
Heide, Muckenfuß
Publikováno v:
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 60(11)
The number of falsified medicines on the German market has distinctly increased over the past few years. In particular, stolen pharmaceutical products, a form of falsified medicines, have increasingly been introduced into the legal supply chain via p
Autor:
Carsten Münk, Ralf Sanzenbacher, Egbert Flory, Ananda Ayyappan Jaguva Vasudevan, Ferdinand Kopietz, Melanie Krämer, Heide Muckenfuss, Klaus Cichutek
Publikováno v:
Journal of General Virology. 93:2425-2430
The human immunodeficiency virus type 1 accessory protein Vif is important for viral infectivity because it counteracts the antiviral protein APOBEC3G (A3G). 32P metabolic labelling of stimulated cells revealed in vivo phosphorylation of the control
Autor:
Heide Muckenfuss, Erika Krebil, Christina Schwer, Julia K. Kaiser, Carsten Münk, Egbert Flory, Marion Battenberg, Klaus Cichutek
Publikováno v:
Nucleic Acids Research
APOBEC3G (A3G), a member of the recently discovered family of human cytidine deaminases, is expressed in peripheral blood lymphocytes and has been shown to be active against HIV-1 and other retroviruses. To gain new insights into the transcriptional
Autor:
Egbert Flory, Ulrich Tschulena, Ralf Sanzenbacher, Klaus Cichutek, Andris Avots, Heide Muckenfuss, Matthias Hamdorf
Publikováno v:
Molecular Immunology. 43:1172-1182
The major T cell growth factor interleukin-2 (IL-2) is secreted by activated T cells in response to antigenic stimulation. This requires signal transduction via the CD3/TCR complex and the CD28 coreceptor, leading to activation of mitogen-activated p
Autor:
Yong Boum Kim, Klaus Cichutek, Patrizia Bastone, Uwe Rösler, Nadine Kirchner, Uwe Truyen, Carsten Münk, Marion Battenberg, Fabian Romen, Martin Löchelt, Ali Saïb, Heide Muckenfuss, Egbert Flory
Publikováno v:
Proceedings of the National Academy of Sciences. 102:7982-7987
Genome hypermutation of different orthoretroviruses by cellular cytidine deaminases of the APOBEC3 family during reverse transcription has recently been observed. Lentiviruses like HIV-1 have acquired proteins preventing genome editing in the newly i
Publikováno v:
Journal of International Biotechnology Law. 4
The rapid biotechnological progress has promoted the development of novel medicinal therapies which are currently changing medical practice substantially. Patients may benefit from new opportunities for the treatment of various diseases, but on the o
Autor:
Heide Muckenfuss, Mario Perkovic, Matthias Hamdorf, Gerald G. Schumann, Egbert Flory, Johannes Löwer, Klaus Cichutek, Carsten Münk, Ulrike Held
Publikováno v:
The Journal of biological chemistry. 281(31)
The human cytidine deaminase family APOBEC3 represents a novel group of proteins in the field of innate defense mechanisms that has been shown to be active against a variety of retroviruses. Here we examined whether members of the APO-BEC3 family hav
Autor:
Matthias, Hamdorf, Heide, Muckenfuss, Ulrich, Tschulena, Stephan, Pleschka, Ralf, Sanzenbacher, Klaus, Cichutek, Egbert, Flory
Publikováno v:
Molecular biotechnology. 33(1)
RNA interference (RNAi) has become a powerful tool for the specific silencing of gene transcription. Especially the targeting of genes in mammalian cells has been greatly improved by generating plasmid based and viral vector-based systems. This permi