Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease

Autor: Nyame, Kwamina, Hims, Andy, Aburous, Aya, Laqtom, Nouf N., Dong, Wentao, Medoh, Uche N., Heiby, Julia C., Xiong, Jian, Ori, Alessandro, Abu-Remaileh, Monther

Publikováno v: In Molecular Cell 4 April 2024 84(7):1354-1364

Organelle dysfunction and its contribution to metabolic impairments in aging and age-related diseases

Autor: Heiby, Julia C., Ori, Alessandro

Publikováno v: In Current Opinion in Systems Biology June 2022 30

Conservation of folding and association within a family of spidroin N-terminal domains

Autor: Heiby, Julia C., Rajab, Suhaila, Rat, Charlotte, Johnson, Christopher M., Neuweiler, Hannes

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports

Web spiders synthesize silk fibres, nature’s toughest biomaterial, through the controlled assembly of fibroin proteins, so-called spidroins. The highly conserved spidroin N-terminal domain (NTD) is a pH-driven self-assembly device that connects spi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::70fa4141f77f7ce4d3da9a4f20e08a83
http://link.springer.com/article/10.1038/s41598-017-16881-6

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Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder.

Autor: Ghoochani A; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network; Chevy Chase, MD, 20815, USA.; These authors contributed equally., Heiby JC; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) e.V., Jena, Germany.; These authors contributed equally., Rawat ES; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network; Chevy Chase, MD, 20815, USA., Medoh UN; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network; Chevy Chase, MD, 20815, USA.; Current affiliation: Arc Institute, Palo Alto, CA 94304, USA., Di Fraia D; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) e.V., Jena, Germany.; Current affiliation: Department of Biology, University of Rochester, Rochester, NY, USA., Dong W; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network; Chevy Chase, MD, 20815, USA., Gastou M; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, 94305, USA., Nyame K; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network; Chevy Chase, MD, 20815, USA., Laqtom NN; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network; Chevy Chase, MD, 20815, USA., Gomez-Ospina N; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, 94305, USA., Ori A; Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) e.V., Jena, Germany.; Co-senior authors., Abu-Remaileh M; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Genetics, Stanford University, Stanford, CA 94305, USA.; The Institute for Chemistry, Engineering and Medicine for Human Health (Sarafan ChEM-H), Stanford University, Stanford, CA 94305, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network; Chevy Chase, MD, 20815, USA.; The Phil & Penny Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.; Co-senior authors.; Lead author.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.