Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Hei Sook, Sul"'
Autor:
Sarah Séité, Mark C. Harrison, David Sillam-Dussès, Roland Lupoli, Tom J. M. Van Dooren, Alain Robert, Laure-Anne Poissonnier, Arnaud Lemainque, David Renault, Sébastien Acket, Muriel Andrieu, José Viscarra, Hei Sook Sul, Z. Wilhelm de Beer, Erich Bornberg-Bauer, Mireille Vasseur-Cognet
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Séité, Harrison, et al. investigate the mechanisms underlying long lifespan in queens and kings of the highly social termite Macrotermes natalensis. Using transcriptomics, lipidomics and metabolomics, this study shows that several aging-related pro
Externí odkaz:
https://doaj.org/article/b08c6c5bde544ce89bcde867e5dcd68a
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
In response to insulin, liver cells increase de novo lipogenesis via the transcription factors USF-1 and SREBP. Here the authors show that USF-1 recruits JMJD1C, after its phosphorylation by mTOR, to lipogenic promoters where JMJD1C demethylates hist
Externí odkaz:
https://doaj.org/article/b00b481391d4487aa57db0dfdc9af5fd
Autor:
Chihiro Tabuchi, Hei Sook Sul
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/7cd39012b6484a80a9e14e778652507e
Autor:
Purna A. Joshi, Paul D. Waterhouse, Katayoon Kasaian, Hui Fang, Olga Gulyaeva, Hei Sook Sul, Paul C. Boutros, Rama Khokha
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The origin and source of mammary gland progenitors and how they interact with the adipose‐rich stroma is unclear. Here, the authors identify PDGFRα+ adipocyte progenitors in the murine mammary stroma as a mesenchymal cell lineage recruited into th
Externí odkaz:
https://doaj.org/article/ca3212bb13c842369939f7f12391cab1
Autor:
Chihiro Tabuchi, Hei Sook Sul
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Obesity, an excess accumulation of white adipose tissue (WAT), has become a global epidemic and is associated with complex diseases, such as type 2 diabetes and cardiovascular diseases. Presently, there are no safe and effective therapeutic agents to
Externí odkaz:
https://doaj.org/article/ba7802187985499f8bf57c08e0f48773
Autor:
Danielle Yi, Hai P Nguyen, Jennie Dinh, Jose A Viscarra, Ying Xie, Frances Lin, Madeleine Zhu, Jon M Dempersmier, Yuhui Wang, Hei Sook Sul
Publikováno v:
eLife, Vol 9 (2020)
Brown adipose tissue is a metabolically beneficial organ capable of dissipating chemical energy into heat, thereby increasing energy expenditure. Here, we identify Dot1l, the only known H3K79 methyltransferase, as an interacting partner of Zc3h10 tha
Externí odkaz:
https://doaj.org/article/8291e8d55a79464fb91118053d19a7ab
Autor:
Danielle Yi, Jon M. Dempersmier, Hai P. Nguyen, Jose A. Viscarra, Jennie Dinh, Chihiro Tabuchi, Yuhui Wang, Hei Sook Sul
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2621-2633.e4 (2019)
Summary: Brown adipose tissue harbors UCP1 to dissipate chemical energy as heat. However, the transcriptional network that governs the thermogenic gene program is incompletely understood. Zc3h10, a CCCH-type zinc finger protein, has recently been rep
Externí odkaz:
https://doaj.org/article/6726b93cd7e044bfb9c3959addea4935
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 1002-1017.e4 (2018)
Summary: Adipocytes arise from the commitment and differentiation of adipose precursors in white adipose tissue (WAT). In studying adipogenesis, precursor markers, including Pref-1 and PDGFRα, are used to isolate precursors from stromal vascular fra
Externí odkaz:
https://doaj.org/article/8419b2ebf71143ba87fc2ef9cf54a524
Autor:
Audrey Sambeat, Olga Gulyaeva, Jon Dempersmier, Kevin M. Tharp, Andreas Stahl, Sarah M. Paul, Hei Sook Sul
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2536-2549 (2016)
Zfp516, a brown fat (BAT)-enriched and cold-inducible transcription factor, promotes transcription of UCP1 and other BAT-enriched genes for non-shivering thermogenesis. Here, we identify lysine-specific demethylase 1 (LSD1) as a direct binding partne
Externí odkaz:
https://doaj.org/article/8d6155f5d17748d69b0da7b6564229f5
Autor:
Yuhui Wang, Hai P Nguyen, Pengya Xue, Ying Xie, Danielle Yi, Frances Lin, Jose A Viscarra, Nnejiuwa U Ibe, Robin E Duncan, Hei Sook Sul
ApoL6 is a new LD-associated protein containing an apoprotein-like domain, expressed mainly in adipose tissue, specifically in adipocytes. ApoL6 expression is low in fasting but induced upon feeding. ApoL6 knockdown results in smaller LD with lower t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e363904ebcd002e143eafb449db377f
https://doi.org/10.1101/2022.11.10.516022
https://doi.org/10.1101/2022.11.10.516022