Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hehuan Lai"'
Autor:
Hehuan Lai, Jialin Fan, Yejin Zhang, Bin Pan, Wenzheng Pan, Jiawei Fang, Kainan Ni, Zhenzhong Chen, Shijie Liu, Chao Lou, Dengwei He
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 2, Pp 157-163 (2023)
Objective(s): Recently, studies on microRNAs (miRNAs) and their targets and related genes have provided new therapeutic opportunities for controlling intervertebral disc degeneration (IDD). We aimed to investigate the effects of miR-148a-3p overexpre
Externí odkaz:
https://doaj.org/article/2f69423e4b234b13bdf8190822bd2d64
Autor:
Bin Pan, Lin Zheng, Shijie Liu, Jiawei Fang, Chao Lou, Xingyu Hu, Lin Ye, Hehuan Lai, Jiawei Gao, Yejin Zhang, Kainan Ni, Dengwei He
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Bone metabolic homeostasis is largely dependent on the dynamic balance between osteoblasts and osteoclasts. MicroRNAs (miRNAs) play critical roles in regulating bone metabolism. In this study, we explored the role of a new miRNA (miR-148a) i
Externí odkaz:
https://doaj.org/article/0e5987aa2b5540109a14adfd373cbdf4
Autor:
Bin Pan, Lin Zheng, Jiawei Fang, Ye Lin, Hehuan Lai, Jiawei Gao, Wenzheng Pan, Yejin Zhang, Kainan Ni, Chao Lou, Dengwei He
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Osteoporosis is characterized by a decrease in bone mass and destruction of the bone microarchitecture, and it commonly occurs in postmenopausal women and the elderly. Overactivation of osteoclasts caused by the inflammatory response or oxidative str
Externí odkaz:
https://doaj.org/article/9f7d8149ba67406f8401abd0d475ae73
Autor:
Hehuan Lai, Jialin Fan, Huan Liu, Xiufen Wu, Lingming Wang, Liumei Gao, Lili Zhou, Tingting Chen, Le Zhang, Jing Chen, Zhiping Luo
Publikováno v:
Archives of Osteoporosis. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf71cc2c1f3b0699dffc4d03edaec241
https://doi.org/10.1007/s11657-023-01221-1
https://doi.org/10.1007/s11657-023-01221-1
Autor:
Tingting Nie, Fenglan Li, Ying Chen, Hehuan Lai, Yitong Zhang, Hui Li, Jiaqi Tao, Tingting Lin, Tangdong Ge
Publikováno v:
Biological Trace Element Research. 199:185-196
Previous studies have raised concerns that kidney disease is often closely related to low serum Se levels in patients and that hyposelenemia may increase the vulnerability of patients to complications. However, few studies examining renal injury caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716d4f5b5df82c201e1799d4405cabd3
https://doi.org/10.1007/s12011-020-02112-z
https://doi.org/10.1007/s12011-020-02112-z
Autor:
Chao Lou, Hehuan Lai, Bin Pan, Lin Zheng, Lin Ye, Zhenzhong Chen, Dengwei He, Jiawei Gao, Wenzheng Pan, Shijie Liu, Shunwu Fan
Publikováno v:
International Journal of Oncology
Osteosarcoma (OS) is the most common malignant bone tumor and the long‑term survival rates remain unsatisfactory. Transforming growth factor‑β (TGF‑β) has been revealed to play a crucial role in OS progression, and RepSox is an effective TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206ad45882997189264d660974d9229d
http://europepmc.org/articles/PMC8460063
http://europepmc.org/articles/PMC8460063
Autor:
Hehuan Lai, Dengwei He, Bin Pan, Chao Lou, Wenzheng Pan, Jiawei Gao, Jiawei Fang, Shijie Liu, Lin Ye, Lin Zheng, Yejin Zhang, Zhenzhong Chen, Kainai Ni
Publikováno v:
Biochemical pharmacology. 195
Osteoporosis is a metabolic disorder of reduced bone mass, accompanied by the deterioration of the bone microstructure, resulting in increased brittleness and easy fracture. Its pathogenesis can be explained by mainly excessive osteoclast formation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838721c7cde5bd22cab4551f53cebb37
https://pubmed.ncbi.nlm.nih.gov/34801525
https://pubmed.ncbi.nlm.nih.gov/34801525
Autor:
Xiaoyan Hu, Wanpeng Cheng, Tingting Nie, Mengdi Li, Hui Li, Jincheng Luo, Fenglan Li, Hehuan Lai, Xiaolin Zheng
Publikováno v:
Placenta. 55:81-89
Selenocysteine insertion binding protein 2 (SECISBP2) plays a vital role in selenocysteine incorporation into selenoprotein in many creatures. However, the impact of SECISBP2 in development of trophoblast cells remains unclear. The aim of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad365b3ecdc7066a5ab95c4b22d2a474
https://doi.org/10.1016/j.placenta.2017.05.007
https://doi.org/10.1016/j.placenta.2017.05.007
Autor:
Hehuan Lai, Jincheng Luo, Tingting Nie, Xiaoyan Hu, Wanpeng Cheng, Mengdi Li, Hui Li, Fenglan Li
Publikováno v:
Biological trace element research. 184(1)
Selenoprotein K (SelK), a member of selenoprotein family, is identified as a single endoplasmic reticulum (ER) transmembrane protein. Although over-expression of SelK inhibits adherence and migration of human gastric cancer BGC-823 cells, the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5041c4d5e8d2708d57ef36706123431
https://pubmed.ncbi.nlm.nih.gov/28983820
https://pubmed.ncbi.nlm.nih.gov/28983820
MicroRNA-328 is involved in the effect of selenium on hydrogen peroxide-induced injury in H9c2 cells
Autor:
Xiaolin, Zheng, Xiaoyan, Hu, Tangdong, Ge, Mengdi, Li, Minxia, Shi, Jincheng, Luo, Hehuan, Lai, Tingting, Nie, Fenglan, Li, Hui, Li
Publikováno v:
Journal of biochemical and molecular toxicology. 31(8)
Oxidative stress induces apoptosis in cardiac cells, and antioxidants attenuate the injury. MicroRNAs (miRNAs) are also involved in cell death; therefore, this study aimed to investigate the role of miRNAs in the effect of selenium on oxidative stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88a84cd557b7b58df3a02df3dbf38c2e
https://pubmed.ncbi.nlm.nih.gov/28544404
https://pubmed.ncbi.nlm.nih.gov/28544404