Zobrazeno 1 - 10
of 1 608
pro vyhledávání: '"Heguy A"'
Autor:
Theodore Sakellaropoulos, Catherine Do, Guimei Jiang, Giulia Cova, Peter Meyn, Dacia Dimartino, Sitharam Ramaswami, Adriana Heguy, Aristotelis Tsirigos, Jane A. Skok
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Aberrations in the capacity of DNA/chromatin modifiers and transcription factors to bind non-coding regions can lead to changes in gene regulation and impact disease phenotypes. However, identifying distal regulatory elements and connecting
Externí odkaz:
https://doaj.org/article/25fc948f3f434d049d7610ff9b16694c
Autor:
Pan, Wanqing, Zhang, Weimin, Zheng, Binghan, Camellato, Brendan R., Stern, Jeffrey, Lin, Ziyan, Khodadadi-Jamayran, Alireza, Kim, Jacqueline, Sommer, Philip, Khalil, Karen, Weldon, Elaina, Bai, Jiangshan, Zhu, Yinan, Meyn, Peter, Heguy, Adriana, Mangiola, Massimo, Griesemer, Adam, Keating, Brendan J., Montgomery, Robert A., Xia, Bo, Boeke, Jef D.
Publikováno v:
In Med 9 August 2024 5(8):1016-1029
Autor:
Igor Dolgalev, Hua Zhou, Nina Murrell, Hortense Le, Theodore Sakellaropoulos, Nicolas Coudray, Kelsey Zhu, Varshini Vasudevaraja, Anna Yeaton, Chandra Goparaju, Yonghua Li, Imran Sulaiman, Jun-Chieh J. Tsay, Peter Meyn, Hussein Mohamed, Iris Sydney, Tomoe Shiomi, Sitharam Ramaswami, Navneet Narula, Ruth Kulicke, Fred P. Davis, Nicolas Stransky, Gromoslaw A. Smolen, Wei-Yi Cheng, James Cai, Salman Punekar, Vamsidhar Velcheti, Daniel H. Sterman, J. T. Poirier, Ben Neel, Kwok-Kin Wong, Luis Chiriboga, Adriana Heguy, Thales Papagiannakopoulos, Bettina Nadorp, Matija Snuderl, Leopoldo N. Segal, Andre L. Moreira, Harvey I. Pass, Aristotelis Tsirigos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Approximately 30% of early-stage lung adenocarcinoma patients present with disease progression after successful surgical resection. Despite efforts of mapping the genetic landscape, there has been limited success in discovering predictive bi
Externí odkaz:
https://doaj.org/article/326ae301e3024de2b6652801e0ebede8
Autor:
Samantha K. Smith, Paul W. Frazel, Alireza Khodadadi-Jamayran, Paul Zappile, Christian Marier, Mariam Okhovat, Stuart Brown, Michael A. Long, Adriana Heguy, Steven M. Phelps
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Developing genomic resources for a diverse range of species is an important step towards understanding the mechanisms underlying complex traits. Specifically, organisms that exhibit unique and accessible phenotypes-of-interest all
Externí odkaz:
https://doaj.org/article/798eb7a09956465eb3041f88f28ffb5e
Autor:
Ralf Duerr, Dacia Dimartino, Christian Marier, Paul Zappile, Guiqing Wang, Fritz François, Mila B. Ortigoza, Eduardo Iturrate, Marie I. Samanovic, Mark J. Mulligan, Adriana Heguy
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104843- (2023)
Summary: Background: High rates of vaccination and natural infection drive immunity and redirect selective viral adaptation. Updated boosters are installed to cope with drifted viruses, yet data on adaptive evolution under increasing immune pressure
Externí odkaz:
https://doaj.org/article/9a42314292244bbf8ac8b08f64d79d3b
Autor:
Duerr, Ralf, Dimartino, Dacia, Marier, Christian, Zappile, Paul, Wang, Guiqing, François, Fritz, Ortigoza, Mila B., Iturrate, Eduardo, Samanovic, Marie I., Mulligan, Mark J., Heguy, Adriana
Publikováno v:
In eBioMedicine November 2023 97
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Gregor Werba, Daniel Weissinger, Emily A. Kawaler, Ende Zhao, Despoina Kalfakakou, Surajit Dhara, Lidong Wang, Heather B. Lim, Grace Oh, Xiaohong Jing, Nina Beri, Lauren Khanna, Tamas Gonda, Paul Oberstein, Cristina Hajdu, Cynthia Loomis, Adriana Heguy, Mara H. Sherman, Amanda W. Lund, Theodore H. Welling, Igor Dolgalev, Aristotelis Tsirigos, Diane M. Simeone
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) is a complex ecosystem that drives tumor progression; however, in-depth single cell characterization of the PDAC TME and its role in response to therapy is lacking.
Externí odkaz:
https://doaj.org/article/3a27bc68fbda40dca2027e7c95c28684
Publikováno v:
Respiratory Research, Vol 8, Iss 1, p 10 (2007)
Abstract Background Cigarette smoke disrupts the protective barrier established by the airway epithelium through direct damage to the epithelial cells, leading to cell death. Since the morphology of the airway epithelium of smokers does not typically
Externí odkaz:
https://doaj.org/article/64319dc6508a496d8f04cfbe7ee20521