Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hege H. Slagsvold"'
Publikováno v:
Traffic. 7:663-672
Ricin is transported from early endosomes and/or the recycling compartment to the trans-Golgi network (TGN) and subsequently to the endoplasmic recticulum (ER) before it enters the cytosol and intoxicates cells. We have investigated the role of the R
Autor:
Tore Geir Iversen, Maria Lyngaas Torgersen, Sébastien Wälchli, Kirsten Sandvig, Bjørn Spilsberg, Hege H. Slagsvold, Silje Ugland Lauvrak
Publikováno v:
Molecular Biology of the Cell. 17:1096-1109
Shiga toxin (Stx) is composed of an A-moiety that inhibits protein synthesis after translocation into the cytosol, and a B-moiety that binds to Gb3 at the cell surface and mediates endocytosis of the toxin. After endocytosis, Stx is transported retro
Autor:
Erica Khuong, Chris M. Jacobs, Ragnhild E. Paulsen, Hege H. Slagsvold, Nina Kristoffersen, Mona Gaarder, Carola M. Rosseland, Åsa B. Fallgren, Henrik S. Huitfeldt
Publikováno v:
Brain Research. 984:111-121
Many recent reports on internucleosomal DNA fragments have appeared, however, little is known about the mechanisms of the generation of their upstream high molecular weight (HMW) fragments. Caspases are a family of proteases with important functions
Publikováno v:
Biochemical and Biophysical Research Communications. 291:1146-1150
NGFI-B is an inducible orphan nuclear receptor that initiates apoptosis. Growth factors such as EGF activate the MAP kinase ERK, whose activity may determine if a cell survives or undergoes apoptosis. EGF stimulation of cells leads to phosphorylation
Publikováno v:
Biochemical and biophysical research communications. 358(2)
The bacterial toxin Shiga toxin (Stx) is transported retrogradely from early endosomes to the Golgi apparatus on its way to the endoplasmic reticulum (ER) and the cytosol. In this study we explored the functions of the two phosphoinositide binding pr
Publikováno v:
Experimental brain research. 135(2)
In cerebellar granule cells a rapid necrotic cell death has been observed during and immediately after glutamate exposure, followed by a delayed apoptotic type of neuronal death in a subpopulation of the surviving neurons. In some experimental models