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A genome-wide scan in 301 families with sibling-pairs diagnosed with schizophrenia of schizoaffective disorder suggests linkage to chromosomes 2pcen and 10p14

Autor: Delisi, L. E., Shaw, S. H., Crow, T. J., Shields, G., Smith, A. B., Larach, V. W., Wellman, N., Loftus, J., Nathankumar, B., Razi, K., Stewart, J., Comazzi, M., Antonio Vita, Sherrington, R., Heffner, T.

Publikováno v: Università degli Studi di Brescia-IRIS

In recent years genome-wide scans and association studies for schizophrenia susceptibility genes have been published. Some have yielded significant positive findings, but there is disagreement between studies concerning their location. No mutation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::979bf6e5c751e26944a035120c1d86c5
https://ora.ox.ac.uk/objects/uuid:17e4ad9d-c2c3-4091-bc44-d07ba7ff0de3

Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib:A multicenter international myeloma working group study

Autor: Kumar S. K., Lee J. H., Lahuerta J. J., Morgan G., Richardson P. G., Crowley J., Haessler J., Feather J., Hoering A., Moreau P., LeLeu X., Hulin C., Klein S. K., Sonneveld P., Siegel D., Bladé J., Goldschmidt H., Jagannath S., Miguel J. S., Orlowski R., Palumbo A., Sezer O., Rajkumar S. V., Durie B. G. International Myeloma Working Group Abildgaard N, Abonour R, Alexanian R, Alsina M, Anderson KC, Attal M, Avet Loiseau H, Badros A, Baris D, Barlogie B, Bataille R, Beksaç M, Belch A, Ben Yehuda D, Bensinger B, Bergsagel PL, Bird J, Bladé J, Boccadoro M, Chanan Khan A, Chen WM, Child T, Chim J, Chng WJ, Comenzo R, Crowley J, Dalton W, Davies F, de Souza C, Delforge M, Dimopoulos M, Dispenzieri A, Drach J, Drake M, Durie BG, Einsele H, Facon T, Fantl D, Fermand JP, Fonseca R, Gahrton G, García Sanz R, Gasparetto C, Gertz M, Gibson J, Giralt S, Goldschmidt H, Greipp P, Hajek R, Hardan I, Hari P, Harousseau JL, Hata H, Hattori Y, Heffner T, Ho J, Hungria V, Ida S, Jacobs P, Jagannath S, Johnsen HE, Jian H, Joshua D, Jurczyszyn A, Kawano M, Kröger N, Kumar S, Kyle RA, Lacy M, Lahuerta JJ, Landgren O, Laubach J, Lee JH, LeLeu X, Lentzsch S, Lokhorst H, Lonial S, Ludwig H, Maiolino A, Mateos M, Mehta J, Mellqvist UH, Merlini G, Mikhael J, Morales AR, Moreau P, Morgan G, Nahi H, Munshi N, Niesvizky R, Nouel A, Novis Y, Orlowski R, Palumbo A, Pavlovsky S, Pilarski L, Powles R, Raje N, Rajkumar SV, Reece D, Reiman T, Richardson PG, Roodman D, Rosiñol L, San Miguel J, Sezer O, Shah JJ, Shaughnessy J, Shimizu K, Shustik C, Siegel D, Singhal S, Sonneveld P, Spencer A, Stadtmauer E, Stewart K, Terpos E, Tosi P, Tricot G, Turesson I, Van Camp B, Van Ness B, Van Riet I, Vande Broek I, Vanderkerken K, Vescio R, Vesole D, Waage A, Wang M, Weber D, Westin J, Wheatley K, Zonder J., CAVO, MICHELE

Publikováno v: Kumar, S K, Lee, J H, Lahuerta, J J, Morgan, G, Richardson, P G, Crowley, J, Haessler, J, Feather, J, Hoering, A, Moreau, P, Leleu, X, Hulin, C, Klein, S K, Sonneveld, P, Siegel, D, Bladé, J, Goldschmidt, H, Jagannath, S, Miguel, J S, Orlowski, R, Palumbo, A, Sezer, O, Rajkumar, S V, Durie, B G M, Abildgaard, N, Abonour, R, Alexanian, R, Alsina, M, Anderson, K C, Attal, M, Avet-Loiseau, H, Badros, A, Baris, D, Barlogie, B, Bataille, R, Beksaç, M, Belch, A, Ben-Yehuda, D, Bensinger, B, Leif Bergsagel, P, Bird, J, Bladé, J, Boccadoro, M, Cavo, M, Chanan-Khan, A, Ming Chen, W, Child, T, Chim, J, Chng, W-J, Johnsen, H & on behalf of the International Myeloma Working Group 2012, ' Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib : A multicenter international myeloma working group study ', Leukemia, vol. 26, no. 1, pp. 149-57 . https://doi.org/10.1038/leu.2011.196
Kumar, S K, Lee, JH, Lahuerta, J J, Morgan, G, Richardson, P G, Crowley, J, Haessler, J, Feather, J, Hoering, A, Moreau, P, LeLeu, X, Hulin, C, Klein, S K, Sonneveld, P, Siegel, D, Bladé, J, Goldschmidt, H, Jagannath, S, Miguel, J S, Orlowski, R, Palumbo, A, Sezer, O, Rajkumar, S V, Durie, B G M, International Myeloma Working Group & Abildgaard, N 2012, ' Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib : a multicenter international myeloma working group study ', Leukemia, vol. 26, no. 1, pp. 149-57 . https://doi.org/10.1038/leu.2011.196
Leukemia, 26(1), 149-157. Nature Publishing Group

Promising new drugs are being evaluated for treatment of multiple myeloma (MM), but their impact should be measured against the expected outcome in patients failing current therapies. However, the natural history of relapsed disease in the current er

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2dbe6ffe8c2635e6295f17f425b101c
https://pure.au.dk/portal/da/publications/risk-of-progression-and-survival-in-multiple-myeloma-relapsing-after-therapy-with-imids-and-bortezomib(9b065552-2900-4784-9cd2-fd53f87d51ac).html

Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study

Autor: Kumar, Sk, Lee, Jh, Lahuerta, Jj, Morgan, G, Richardson, Pg, Crowley, J, Haessler, J, Feather, J, Hoering, A, Moreau, P, Leleu, X, Hulin, C, Klein, Sk, Sonneveld, P, Siegel, D, Bladé, J, Goldschmidt, H, Jagannath, S, Miguel, Js, Orlowski, R, Palumbo, Antonio, Sezer, O, Rajkumar, Sv, Durie, Bg, on behalf of the International Myeloma Working Group, International Myeloma Working Group, Abildgaard, N, Abonour, R, Alexanian, R, Alsina, M, Anderson, Kc, Attal, M, Avet Loiseau, H, Badros, A, Baris, D, Barlogie, B, Bataille, R, Beksaç, M, Belch, A, Ben Yehuda, D, Bensinger, B, Leif Bergsagel, P, Bird, J, Boccadoro, M, Cavo, M, Chanan Khan, A, Ming Chen, W, Child, T, Chim, J, Chng, Wj, Comenzo, R, Dalton, W, Davies, F, de Souza, C, Delforge, M, Dimopoulos, M, Dispenzieri, A, Drach, J, Drake, M, Einsele, H, Facon, T, Fantl, D, Fermand, Jp, Fonseca, R, Gahrton, G, García Sanz, R, Gasparetto, C, Gertz, M, Gibson, J, Giralt, S, Greipp, P, Hajek, R, Hardan, I, Hari, P, Harousseau, Jl, Hata, H, Hattori, Y, Heffner, T, Ho, J, Hungria, V, Ida, S, Jacobs, P, Johnsen, H, Jian, H, Joshua, D, Jurczyszyn, A, Kawano, M, Kröger, N, Kumar, S, Kyle, Ra, Lacy, M, Landgren, O, Laubach, J, Lentzsch, S, Lokhorst, H, Lonial, S, Ludwig, H, Maiolino, A, Mateos, M, Mehta, J, Mellqvist, Uh, Merlini, G, Mikhael, J, Morales, Ar, Nari, H, Munshi, N, Niesvizky, R, Nouel, A, Novis, Y, Palumbo, A, Pavlovsky, S, Pilarski, L, Powles, R, Raje, N, Vincent Rajkumar, S, Reece, D, Reiman, T, Roodman, D, Rosiñol, L, Shah, Jj, Shaughnessy, J, Shimizu, K, Shustik, C, Singhal, S, Spencer, A, Stadtmauer, E, Stewart, K, Terpos, E, Tosi, P, Tricot, G, Turesson, I, Van Camp, B, Van Ness, B, Van Riet, I, Broek, Iv, Vanderkerken, K, Vescio, R, Vesole, D, Waage, A, Wang, M, Weber, D, Westin, J, Wheatley, K, Zonder, J.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______970::4b89415926dbac1eabe46eb5de071655
http://hdl.handle.net/2318/101332

Significant evidence for a schizophrenia susceptibility locus in the centromeric region of human chromosome

Autor: Shaw, S. H., Shields, G., Smith, A. B., Larach, V. W., Wellman, N., Loftus, J., Nanthankumar, B., Razi, K., Stewart, J., Comazzi, M., Antonio Vita, Heffner, T., Sherrington, R., Crow, T. J., Delisi, L. E.

Publikováno v: Università degli Studi di Brescia-IRIS

We have recently completed a genome-wide search for schizophrenia susceptibility genes in a collection of 301 pedigrees resulting in one significant (lod = 3.6, 10p14) and two suggestive (2cen, lod = 2.9; 3q27, lod = 2.3) linkage regions (DeLisi et a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::391d761da7a3908a1797d95e0097aec8
http://ora.ox.ac.uk/objects/uuid:56b9cedb-e19c-4f00-85a1-0890aa59cb02