Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Heeyoung Seok"'
Autor:
Hwalin Yi, Yejin Yun, Won Hoon Choi, Hye-Yeon Hwang, Ju Hyuen Cha, Heeyoung Seok, Jae-Jin Song, Jun Ho Lee, Sang-Yeon Lee, Daesik Kim
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102199- (2024)
Pathogenic structure variations (SVs) are associated with various types of cancer and rare genetic diseases. Recent studies have used Cas9 nuclease with paired guide RNAs (gRNAs) to generate targeted chromosomal rearrangements, focusing on producing
Externí odkaz:
https://doaj.org/article/8c333f9f30f44066829147680fbc0ce9
Autor:
Sang-Yeon Lee, Min Young Kim, Jin Hee Han, Sang Soo Park, Yejin Yun, Seung-Cheol Jee, Jae Joon Han, Jun Ho Lee, Heeyoung Seok, Byung Yoon Choi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract POU4F3, a member of the POU family of transcription factors, commonly causes autosomal dominant deafness. Exome sequencing was used to identify four novel variants in POU4F3 (NM_002700.2), including c.564dupA: p.Ala189SerfsTer26, c.743T > C:
Externí odkaz:
https://doaj.org/article/9c67b1fd58ab4b5b843076a19b199600
Publikováno v:
Clinical and Experimental Pediatrics, Vol 65, Iss 5, Pp 230-238 (2022)
Myocarditis was previously attributed to an epidemic viral infection. Additional harmful reagents, in addition to viruses, play a role in its etiology. Coronavirus disease 2019 (COVID-19) vaccine-induced myocarditis has recently been described, drawi
Externí odkaz:
https://doaj.org/article/1050fb0afb5d4c58a79de1233790d477
KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state
Autor:
Jin-Woo Lee, Jin Hur, Yoo-Wook Kwon, Cheong-Whan Chae, Jae-Il Choi, Injoo Hwang, Ji-Yeon Yun, Jin-A Kang, Young-Eun Choi, Young Hyun Kim, Sang Eun Lee, Cheol Lee, Dong Hyun Jo, Heeyoung Seok, Byong Seung Cho, Sung Hee Baek, Hyo-Soo Kim
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-21 (2021)
Abstract Background Little is known about endogenous inhibitors of angiogenic growth factors. In this study, we identified a novel endogenous anti-angiogenic factor expressed in pericytes and clarified its underlying mechanism and clinical significan
Externí odkaz:
https://doaj.org/article/791b651888294fddb7d39ceb1e7fbdc8
Publikováno v:
Clinical and Experimental Pediatrics, Vol 64, Iss 6, Pp 269-279 (2021)
Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR-Cas9) is an ancient prokaryotic defense system that precisely cuts foreign genomic DNA under the control of a small number of guide RNAs. The CRISPR-Cas
Externí odkaz:
https://doaj.org/article/b04e827759264f73944377a3ec695972
Publikováno v:
Clinical and Experimental Pediatrics
Clinical and Experimental Pediatrics, Vol 64, Iss 6, Pp 269-279 (2021)
Clinical and Experimental Pediatrics, Vol 64, Iss 6, Pp 269-279 (2021)
Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR-Cas9) is an ancient prokaryotic defense system that precisely cuts foreign genomic DNA under the control of a small number of guide RNAs. The CRISPR-Cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962c8f1584e9c6cdac295f7b3df53adb
https://doi.org/10.3345/cep.2020.02096
https://doi.org/10.3345/cep.2020.02096
Autor:
Heeyoung Seok, Jin Hee Oh
Publikováno v:
Korean Circulation Journal
Author's summary Hypertrophic cardiomyopathy (HCM) in infancy is rare and many fulminant cases are fatal. Infantile HCM shows a rapid progressive clinical course and different characteristics compared with late-onset HCM presenting during the prepube
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c100d58608db2deaa18ad21685dab6ce
http://europepmc.org/articles/PMC8424452
http://europepmc.org/articles/PMC8424452
KAI1(CD82) is a key molecule to control angiogenesis and switch angiogenic milieu to quiescent state
Autor:
Dong Hyun Jo, Cheong Whan Chae, Sang Eun Lee, Yoo Wook Kwon, Cheol Lee, Jin Woo Lee, Younghyun Kim, Young Eun Choi, Heeyoung Seok, Jin A. Kang, Sung Hee Baek, Injoo Hwang, Hur Jin, Ji Yeon Yun, Hyo-Soo Kim, Jae Il Choi, Byong Seung Cho
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-21 (2021)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
Background Little is known about endogenous inhibitors of angiogenic growth factors. In this study, we identified a novel endogenous anti-angiogenic factor expressed in pericytes and clarified its underlying mechanism and clinical significance. Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f808c248e3d7ab1b1cfdccb3e306d40d
https://doi.org/10.1186/s13045-021-01147-6
https://doi.org/10.1186/s13045-021-01147-6
Autor:
Seung Hyun Ahn, Jongyeun Park, Sohyun Lee, Heeyoung Seok, Sung Wook Chi, Yeojin Jeong, You Kyung Cho, Hye Sook Lee, Dowoon Gu, Yeahji Jeong, Jongjin Peak, Geun Don Kim, Haejeong Lee, Eun Sook Jang, Sangkyeong Eom
Publikováno v:
Nature. 584(7820)
In pathophysiology, reactive oxygen species oxidize biomolecules that contribute to disease phenotypes1. One such modification, 8-oxoguanine2 (o8G), is abundant in RNA3 but its epitranscriptional role has not been investigated for microRNAs (miRNAs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cf563ef1fa25ef63a91b678a0c53db
https://pubmed.ncbi.nlm.nih.gov/32820255
https://pubmed.ncbi.nlm.nih.gov/32820255
Publikováno v:
Molecules and Cells
MicroRNAs (miRNAs) are small non-coding RNAs (∼22 nucleotides) regulating gene expression at the post-transcriptional level. By directing the RNA-induced silencing complex (RISC) to bind specific target mRNAs, miRNA can repress target genes and aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72391a62aed58a0d5d42039b9d27328e
http://europepmc.org/articles/PMC4870184
http://europepmc.org/articles/PMC4870184