Tigilanol Tiglate-Induced Changes in Secretome Profiles Alter C-Met Phosphorylation and Cell Surface Protein Expression in H357 Head and Neck Cancer Cells.

Autor: Antwi FD; School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4XY, UK., Awad T; School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4XY, UK., Larin M; School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4XY, UK., Heesom K; Bristol Proteomics Facility, Biomedical Sciences Building, University Walk, University of Bristol, Bristol BS8 1TD, UK., Lewis P; Bristol Proteomics Facility, Biomedical Sciences Building, University Walk, University of Bristol, Bristol BS8 1TD, UK., Reddell P; QBiotics Group, Yungaburra, QLD 4884, Australia., Poghosyan Z; School of Medicine, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4XN, UK., Dewitt S; School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4XY, UK., Moseley R; School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4XY, UK., Knäuper V; School of Dentistry, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF14 4XY, UK.

Publikováno v: Cells [Cells] 2024 Jun 05; Vol. 13 (11). Date of Electronic Publication: 2024 Jun 05.

Ultrasound modulates neuronal potassium currents via ionotropic glutamate receptors.

Autor: Clennell B; Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, BS1 3NY, UK., Steward TGJ; Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, BS1 3NY, UK., Hanman K; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK., Needham T; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK., Benachour J; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK., Jepson M; Wolfson Bioimaging Facility, Faculty of Life Sciences, University of Bristol, Bristol, BS8 1TD, UK., Elley M; Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, BS1 3NY, UK., Halford N; Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, BS1 3NY, UK., Heesom K; Proteomics Facility Faculty of Life Sciences, University Walk, University of Bristol, Bristol, BS8 1TD, UK., Shin E; School of Life Sciences, Keele University, ST5 5BG, UK., Molnár E; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK., Drinkwater BW; Faculty of Engineering, University of Bristol, Bristol, BS8 1TR, UK., Whitcomb DJ; Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, BS1 3NY, UK. Electronic address: D.J.Whitcomb@Bristol.ac.uk.

Publikováno v: Brain stimulation [Brain Stimul] 2023 Mar-Apr; Vol. 16 (2), pp. 540-552. Date of Electronic Publication: 2023 Jan 31.

Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.

Autor: Yaron TM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine/Memorial Sloan Kettering Cancer Center/Rockefeller University, New York, NY 10021, USA., Heaton BE; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Levy TM; Cell Signaling Technology, Danvers, MA 01923, USA., Johnson JL; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Jordan TX; Grossman School of Medicine, New York University, New York, NY 10016, USA., Cohen BM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Kerelsky A; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Lin TY; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Liberatore KM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Bulaon DK; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Van Nest SJ; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Koundouros N; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA., Kastenhuber ER; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Mercadante MN; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Shobana-Ganesh K; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., He L; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Schwartz RE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Chen S; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA., Weinstein H; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA., Elemento O; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA., Piskounova E; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Dermatology, Weill Cornell Medicine, New York, NY 10065, USA., Nilsson-Payant BE; Grossman School of Medicine, New York University, New York, NY 10016, USA., Lee G; Department of Microbiology and Molecular Genetics, Chao Family Comprehensive Cancer Center, University of California, Irvine School of Medicine, Irvine, CA 92868, USA., Trimarco JD; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Burke KN; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Hamele CE; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Chaparian RR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Harding AT; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Tata A; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Zhu X; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Tata PR; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Smith CM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Possemato AP; Cell Signaling Technology, Danvers, MA 01923, USA., Tkachev SL; Cell Signaling Technology, Danvers, MA 01923, USA., Hornbeck PV; Cell Signaling Technology, Danvers, MA 01923, USA., Beausoleil SA; Cell Signaling Technology, Danvers, MA 01923, USA., Anand SK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Aguet F; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Getz G; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.; Cancer Center and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Davidson AD; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., Heesom K; Proteomics Facility, University of Bristol, Bristol BS8 1TD, UK., Kavanagh-Williamson M; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., Matthews DA; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., tenOever BR; Grossman School of Medicine, New York University, New York, NY 10016, USA., Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Blenis J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA.; Department of Biochemistry, Weill Cornell Medicine, New York, NY 10065, USA., Heaton NS; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC 27710, USA.

Publikováno v: Science signaling [Sci Signal] 2022 Oct 25; Vol. 15 (757), pp. eabm0808. Date of Electronic Publication: 2022 Oct 25.

Reduced expression of mitochondrial fumarate hydratase in progressive multiple sclerosis contributes to impaired in vitro mesenchymal stromal cell-mediated neuroprotection.

Autor: Sarkar P; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Neurology, North Bristol NHS Trust, Southmead Hospital, Bristol, UK., Redondo J; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Hares K; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Bailey S; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Neurology, North Bristol NHS Trust, Southmead Hospital, Bristol, UK., Georgievskaya A; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Heesom K; Bristol Proteomics Facility, Biomedical Sciences, University of Bristol, Bristol, UK., Kemp KC; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Scolding NJ; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Neurology, North Bristol NHS Trust, Southmead Hospital, Bristol, UK., Rice CM; Clinical Neurosciences, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Department of Neurology, North Bristol NHS Trust, Southmead Hospital, Bristol, UK.

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2022 Jul; Vol. 28 (8), pp. 1179-1188. Date of Electronic Publication: 2021 Nov 29.

Effect of cardioplegic arrest and reperfusion on left and right ventricular proteome/phosphoproteome in patients undergoing surgery for coronary or aortic valve disease.

Autor: Abdul-Ghani S; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol BS2 8HW, UK., Skeffington KL; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol BS2 8HW, UK., Kim M; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol BS2 8HW, UK., Moscarelli M; National Heart and Lung Institute, Imperial College, London SW3 6LY, UK., Lewis PA; University of Bristol Proteomics/Bioinformatics Facility, University of Bristol, Bristol BS8 1TD, UK., Heesom K; University of Bristol Proteomics/Bioinformatics Facility, University of Bristol, Bristol BS8 1TD, UK., Fiorentino F; National Heart and Lung Institute, Imperial College, London SW3 6LY, UK., Emanueli C; National Heart and Lung Institute, Imperial College, London SW3 6LY, UK., Reeves BC; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol BS2 8HW, UK., Punjabi PP; National Heart and Lung Institute, Imperial College, London SW3 6LY, UK., Angelini GD; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol BS2 8HW, UK., Suleiman MS; Bristol Heart Institute and Bristol Medical School, University of Bristol, Bristol BS2 8HW, UK.

Publikováno v: International journal of molecular medicine [Int J Mol Med] 2022 Jun; Vol. 49 (6). Date of Electronic Publication: 2022 Apr 15.