Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Heeseung Jo"'
Autor:
Louis Gall, Ferran Jardi, Lieve Lammens, Janet Piñero, Terezinha M. Souza, Daniela Rodrigues, Danyel G. J. Jennen, Theo M. deKok, Luke Coyle, Seung‐Wook Chung, Sofia Ferreira, Heeseung Jo, Kylie A. Beattie, Colette Kelly, Carrie A. Duckworth, D. Mark Pritchard, Carmen Pin
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1511-1528 (2023)
Abstract We have built a quantitative systems toxicology modeling framework focused on the early prediction of oncotherapeutic‐induced clinical intestinal adverse effects. The model describes stem and progenitor cell dynamics in the small intestina
Externí odkaz:
https://doaj.org/article/ad07b2f07f9e481a9365795b33099f08
Autor:
Hiba Khalidi, Anthonia Onasanwo, Barira Islam, Heeseung Jo, Ciarán Fisher, Rich Aidley, Iain Gardner, Frederic Y. Bois
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
SimRFlow is a high-throughput physiologically based pharmacokinetic (PBPK) modelling tool which uses Certara’s Simcyp® simulator. The workflow is comprised of three main modules: 1) a Data Collection module for automated curation of physicochemica
Externí odkaz:
https://doaj.org/article/05e627da92eb40dba6a8e07ee9f1ec40
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 2, Pp 108-118 (2021)
This analysis reports a quantitative modeling and simulation approach for oral dapagliflozin, a primarily uridine diphosphate‐glucuronosyltransferase (UGT)–metabolized human sodium‐glucose cotransporter 2 selective inhibitor. A mechanistic dapa
Externí odkaz:
https://doaj.org/article/04577c1c615147d1a35e59ffeccf1fba
Publikováno v:
Applied Sciences, Vol 12, Iss 14, p 7072 (2022)
Modern Linux operating systems are being used in a wide range of fields, from small IoT embedded devices to supercomputers. However, most machines use the default Linux scheduler parameters implemented for general-purpose environments. The problem is
Externí odkaz:
https://doaj.org/article/c416a00698734f79a11190886f9054be
Autor:
Kangmin Lee, Heeseung Jo
Publikováno v:
IEEE Access, Vol 6, Pp 45417-45426 (2018)
As the many-core processors become more prevalent, the parallelism degree of applications is rapidly increasing. It is well known that multi-thread approaches are an effective solution to improve performance by exploiting multiple cores. However, the
Externí odkaz:
https://doaj.org/article/84704559b04d43b69a35995ec68f4587
Publikováno v:
Applied Sciences, Vol 10, Iss 19, p 6657 (2020)
The resource management of an application is an essential task in smartphones. Optimizing the application launch process results in a faster and more efficient system, directly impacting the user experience. Predicting the next application that will
Externí odkaz:
https://doaj.org/article/8fdf46756b2b43a3b570410cd5995e97
Publikováno v:
Journal of KIISE. 48:1167-1175
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58d1ea08f02e6c26b7f8eb3e7c48c0b3
https://doi.org/10.5626/jok.2021.48.11.1167
https://doi.org/10.5626/jok.2021.48.11.1167
Publikováno v:
British Journal of Clinical Pharmacology. 87:3988-4000
AIMS Herbal products, spices and/or fruits are perceived as inherently healthy; for instance, St. John's wort (SJW) is marketed as a natural antidepressant and patients often self-administer it concomitantly with oncology medications. However, food c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca21d6aba2b378450b266253686cd8f
https://doi.org/10.1111/bcp.14822
https://doi.org/10.1111/bcp.14822
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 2, Pp 108-118 (2021)
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
This analysis reports a quantitative modeling and simulation approach for oral dapagliflozin, a primarily uridine diphosphate-glucuronosyltransferase (UGT)-metabolized human sodium-glucose cotransporter 2 selective inhibitor. A mechanistic dapagliflo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1cd4cb6c2eaa191426c202e9f04af8
https://doaj.org/article/04577c1c615147d1a35e59ffeccf1fba
https://doaj.org/article/04577c1c615147d1a35e59ffeccf1fba
Autor:
Eman El-Khateeb, Heeseung Jo, Shringi Sharma, Amin Rastomi-Hodjegan, Masoud Jamei, Venkatesh Pilla Reddy, Emily Lythgoe, Weifeng Tang, Natalie Giovino
Publikováno v:
British Journal of Clinical Pharmacology
Reddy, V P, El-Khateeb, E, Jo, H, Giovino, N, Lythgoe, E, Sharma, S, Tang, W, Jamei, M & Rastomi-Hodjegan, A 2020, ' Pharmacokinetics under the COVID-19 Storm ', British Journal of Clinical Pharmacology . https://doi.org/10.1111/bcp.14668
Reddy, V P, El-Khateeb, E, Jo, H, Giovino, N, Lythgoe, E, Sharma, S, Tang, W, Jamei, M & Rastomi-Hodjegan, A 2020, ' Pharmacokinetics under the COVID-19 Storm ', British Journal of Clinical Pharmacology . https://doi.org/10.1111/bcp.14668
Aims The storm-like nature of the health crises caused by COVID-19 has led to unconventional clinical trial practices such as the relaxation of exclusion criteria. The question remains: how can we conduct diverse trials without exposing subgroups of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de841a48e8537d31f72d4655b0e7d349
https://doi.org/10.1111/bcp.14668
https://doi.org/10.1111/bcp.14668