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Interference of n-(1-[4-(4-fluorophenoxy) butyl]-piperidinyl)-n-methyl-2-benzothiazolamine with na+/h+ exchange and na+/ca2+ exchange in purified cardiac sarcolemmal membranes

Autor: SCHEUFLER, E, HEERS, C, WILFFERT, B, Peters, Thies, PIERCE, GN

Publikováno v: Arzneimittel-Forschung/drug research, 43-2(11), 1145-1147

The effect of R 56865 (N-[1-[4-(4-fluorophenoxy)butyl]-piperidinyl]-N-methyl-2-benzothiazolamine, CAS 104606-13-5) on Na+/H+ exchange and Na+/Ca2+ exchange was studied in isolated cardiac sarcolemmal vesicles. R 56865 inhibited Na+/H+ exchange with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::cc66afe7c016e2adcfc63dc532bdb80e
https://research.rug.nl/en/publications/53541455-9b57-476a-b7f3-4996e6e41589

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Interference of N-(1-[4-(4-fluophenoxy)butyl]-piperidinyl)-N-methyl-2-benzothiazolamin e with Na+/H+exchange and Na+/Ca2+exchange in purified cardiac sarcolemmal membranes

Autor: Scheufler, E., Heers, C., Wilffert, B., Peters, Thies, Pierce, G.N.

Publikováno v: Arzneimittel-Forschung-Drug research, 43(11), 1145-1147

The effect of R 56865 (N-[1-[4-(4-fluorophenoxy) butyl]-piperidinyl]-N-methyl-2-benzothiazolamine, CAS 104606-13-5) on Na+/H+exchange and Na+/Ca2+exchange was studied in isolated cardiac sarcolemmal vesicles. R 56865 inhibited Na+/H+exchange with an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::c5e483aab23be59aba47d9813a918b0c
https://research.rug.nl/en/publications/b2580f09-5dbe-4597-86ef-2ce0a3d7894b

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Cardiac effects of r-79595 and its isomers (r-80122 and r-80123) in an acute heart-failure model - a new class of cardiotonic agents with highly selective phosphodiesterase-iii inhibitory properties

Autor: SCHNEIDER, J, BECK, E, HEERS, C, CONRAD, C, DECOURCELLES, DD, WILFFERT, B, Peters, Thies

Publikováno v: Naunyn-Schmiedebergs Archives of Pharmacology, 346(5), 563-572. SPRINGER

R 79595 (N-cyclohexyl-N-methyl-2-[[[phenyl (1,2,3,5-tetrahydro-2 oxoimidazo [2,1-b]-quinazolin-7-yl) methylene] amin] oxy] acetamide) and its isomers represent a novel class of compounds with phosphodiesterase (PDE) inhibitory and cardiotonic (positi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::495ecb503cd920f53e19933c7e457ffd
https://research.rug.nl/en/publications/135a04b5-078c-4e23-a1d0-0a5a87476958

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Differential effect of r-56865 on ouabain binding to isolated sarcolemma and intact atrial tissue of guinea-pig

Autor: HEERS, C, SCHEUFLER, E, WILHELM, D, WERMELSKIRCHEN, D, WILFFERT, B, Peters, Thies

Publikováno v: British Journal of Pharmacology, 102(3), 675-678. Wiley-Blackwell

1 R 56865 (N-[1-[4-(4-fluorophenoxy)-butyl]-4-piperidinyl]-N-methyl-2-benzolamine) is a compound known to antagonize cardiac glycoside intoxication. Therefore, the effect of the compound on ouabain binding to intact cardiac tissue as well as cardiac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0cdf8d4b9c3c5a81f390a207097072c5
https://research.rug.nl/en/publications/b490bf85-59ea-45b0-a0ec-9fcfc9b15cff

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