Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Heer, C. de"'
1
Dermatokinetics of didecyldimethylammonium chloride and the influence of some commercial biocidal formulations on its dermal absorption in vitro
Autor: Buist, H.E., Heer, C. de, Burgsteden, J.A. van, Sandt, J.J.M. van de
Publikováno v: Regulatory Toxicology and Pharmacology, 1, 48, 87-92
The in vitro dermal absorption kinetics of didecyldimethylammonium chloride (DDAC) was studied after single and multiple exposure. In addition, the influence of biocidal formulations on the absorption of DDAC was investigated. Following dermal exposu
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3
Effects of single and repeated exposure to biocidal active substances on the barrier function of the skin in vitro
Autor: Buist, H.E., Sandt, J.J.M. van de, Burgsteden, J.A. van, Heer, C. de
Publikováno v: Regulatory Toxicology and Pharmacology, 1, 43, 76-84
The dermal route of exposure is important in worker exposure to biocidal products. Many biocidal active substances which are used on a daily basis may decrease the barrier function of the skin to a larger extent than current risk assessment practice
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5
Prediction of local irritant effects after repeated dermal and respiratory exposure to chemicals
Autor: Rennen, M.A.J., Nordheim, K., Houben, G.F., Heer, C. de
Publikováno v: Regulatory Toxicology and Pharmacology, 3, 36, 253-261
Health risks resulting from occupational exposure to chemicals are controlled by the establishment of acceptable dermal and respiratory exposure levels. Due to a lack of route-specific toxicity data, acceptable levels are frequently established by me
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7
The SCID-hu mouse as a tool in immunotoxicological risk assessment: Effects of 2-acetyl-4(5)-tetrahydroxybutyl-imidazole (THI) and di-n-butyltin dichloride (DBTC) on the human thymus in SCID-hu mice
Autor: Heer, C. de, Schuurman, H.J., Houben, G.F., Pieters, R.H.H., Penninks, A.H., Loveren, H. van
Publikováno v: Toxicology, 1-3, 100, 203-211
SCID mice engrafted with human fetal thymus and liver tissue fragments (SCID-hu mice) are currently considered as a new tool in human immunotoxicological risk assessment. Testing of various immunotoxicants exerting thymotoxicity via different intrath
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9
Vß gene family usage in spontaneous lymphomas of AKR mice: evidence for defective clonal deletion
Autor: Heer, C. de, Geus, B. de, Schuurman, H.J., Loveren, H. van, Rozing, J.
Publikováno v: Developmental immunology, 2, 95-101
T-cell receptor (TCR) ß-chain usage and expression of the CD3, CD4, and CD8 differentiation antigens were analyzed in 14 spontaneous AKR lymphomas. Lymphoma cells massively infiltrated and/or proliferated in the organs analyzed (thymus, spleen, and
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Plný text Recenzováno Digitální knihovna AV ČR
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