Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Heena Khatter"'
Autor:
Laura Marr, Dipsikha Biswas, Leonard A. Daly, Christopher Browning, Sarah C. M. Vial, Daniel P. Maskell, Catherine Hudson, Jay A. Bertrand, John Pollard, Neil A. Ranson, Heena Khatter, Claire E. Eyers, Kei Sakamoto, Elton Zeqiraj
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Glycogen is a major energy reserve in eukaryotes and is synthesised in part by glycogenin (GN) and glycogen synthase (GS). Here, authors describe the structural basis of GS regulation, specifically the mechanism of inactivation by phosphorylation.
Externí odkaz:
https://doaj.org/article/ebd88343f9654958840f440648a3ec68
Autor:
Alexander G. Myasnikov, S. Kundhavai Natchiar, Marielle Nebout, Isabelle Hazemann, Véronique Imbert, Heena Khatter, Jean-François Peyron, Bruno P. Klaholz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
The ribosome of bacteria and other unicellular pathogens is a common target for antibiotic drugs. Here the authors determine a structure of the human ribosome bound to the translation inhibitor cycloheximide, and provide evidence that targeting the r
Externí odkaz:
https://doaj.org/article/5c015c0b3ce04e609d082a4c3d51b4f2
Autor:
Halina Anton, Nedal Taha, Emmanuel Boutant, Ludovic Richert, Heena Khatter, Bruno Klaholz, Philippe Rondé, Eléonore Réal, Hugues de Rocquigny, Yves Mély
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116921 (2015)
The nucleocapsid protein (NCp7) of the Human immunodeficiency virus type 1 (HIV-1) is a small basic protein containing two zinc fingers. About 2000 NCp7 molecules coat the genomic RNA in the HIV-1 virion. After infection of a target cell, the viral c
Externí odkaz:
https://doaj.org/article/e5220d7aff864e33bc63dc204de9be70
Publikováno v:
Current Opinion in Structural Biology
The majority of non-protein-coding RNAs present in eukaryotic cells comprises rRNAs, tRNAs and U6 snRNA that are involved in protein biosynthesis and are synthesized by DNA-dependent-RNA polymerase I and III. The transcription cycle (initiation, elon
Autor:
Karima Tazibt, Lorenza di Pompeo, Kareem Mohideen, Alexander G. Myasnikov, Morgan Torchy, Igor Orlov, Heena Khatter, Jean-François Ménétret, Finaritra Raivoniaina, S. Kundhavai Natchiar, Leonid Andronov, Isabelle M. L. Billas, Hanna Kratzat, Rachel Tabaroni, Alexandre Urzhumtsev, Tatiana Bruxelles, Bruno P. Klaholz, Brice Beinsteiner, Nadia Djabeur, Isabelle Hazemann
Publikováno v:
Biology of the Cell. 109:81-93
After gradually moving away from preparation methods prone to artefacts such as plastic embedding and negative staining for cell sections and single particles, the field of cryo electron microscopy (cryo-EM) is now heading off at unprecedented speed
Autor:
Marcin Jaciuk, Sebastian Glatt, Ting-Yu Lin, Christoph W. Müller, Karin D. Breunig, Heena Khatter, Felix Weis, Carolin Kleindienst, Rościsław Krutyhołowa, Jan Kosinski, Nour El Hana Abbassi, María I. Daudén
Publikováno v:
Science Advances
The catalytic Elp123 subcomplex of Elongator specifically recognizes and binds tRNAs in its active site.
The highly conserved Elongator complex modifies transfer RNAs (tRNAs) in their wobble base position, thereby regulating protein synthesis an
The highly conserved Elongator complex modifies transfer RNAs (tRNAs) in their wobble base position, thereby regulating protein synthesis an
Publikováno v:
Nature
RNA polymerase III (Pol III) and transcription factor IIIB (TFIIIB) assemble together on different promoter types to initiate the transcription of small, structured RNAs. Here we present structures of Pol III preinitiation complexes, comprising the 1
Autor:
Alexander Myasnikov, Kundhavai Natchiar, Marielle Nebout, Isabelle Isabelle Hazemann, Véronique Imbert, Heena Khatter, Jean-François Peyron, Bruno Klaholz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94691282f399b70144801efb5b667b5a
https://doi.org/10.1002/9783527808465.emc2016.6610
https://doi.org/10.1002/9783527808465.emc2016.6610
Autor:
Véronique Imbert, Heena Khatter, Isabelle Hazemann, Marielle Nebout, Alexander G. Myasnikov, S. Kundhavai Natchiar, Bruno P. Klaholz, Jean-François Peyron
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2016, 7, ⟨10.1038/ncomms12856⟩
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Nature Communications, Nature Publishing Group, 2016, 7, ⟨10.1038/ncomms12856⟩
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Many antibiotics in clinical use target the bacterial ribosome by interfering with the protein synthesis machinery. However, targeting the human ribosome in the case of protein synthesis deregulations such as in highly proliferating cancer cells has
Publikováno v:
Nature. 520(7549)
Ribosomes are translational machineries that catalyse protein synthesis. Ribosome structures from various species are known at the atomic level, but obtaining the structure of the human ribosome has remained a challenge; efforts to address this would