Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Heekyung Tak"'
Autor:
Julie L. Eiseman, Guozhang Zhu, Donald J. Creighton, Erin Joseph, Heekyung Tak, Zhe-Bin Zheng
Publikováno v:
Bioconjugate Chemistry. 16:598-607
The incorporation of anticancer prodrugs into polyacrylamide conjugates has been shown to improve tumor targeting via the so-called "enhanced permeability and retention" effect. This strategy has now been expanded to include two different classes of
Autor:
Eugene P. Mazzola, Ryan Oleszewski, Simon F.R. Hinkley, Jennifer A. Moore, Jennifer Squillari, Heekyung Tak, Bruce B. Jarvis
Publikováno v:
Magnetic Resonance in Chemistry. 41:337-343
Publikováno v:
Mycopathologia. 154:41-49
As part of our effort to investigate fungi associated with soybean roots, Stachybotrys chartarum was isolated from soybean root lesions. Since this fungus has not been reported to cause a disease of soybean, the objectives were to identify and charac
Publikováno v:
Spectroscopy Letters. 27:1481-1488
Two melampolide-type sesquiterpene lactones, enhydrin and 2,′ 3′-dehydromelnerin A, were isolated from a Louisiana population of Polymnia uvedalia. Their 13C NMR spectra were assigned using 13C-1H correlation, DEPT and COLOC experiments. The mole
Publikováno v:
Spectroscopy Letters. 27:1431-1435
Aerial parts of Erigeron annuus and E. strigosus afforded 3-hydroxy-4-pyrone, the molecular structure of which was determined by single crystal X-ray diffraction.
Publikováno v:
ChemInform. 25
The title compound, 3-phenyl-1-(2,4,5-trihydroxy-3,5-dimethyl-6-oxo-1,5-cyclohexadienyl)-1-propanone, was confirmed to be a dihydrochalcone containing a fully substituted cyclohexadienone ring. This ring has a flattened half-chair conformation, with
Publikováno v:
Toxicology mechanisms and methods. 13(4)
Although satratoxin G (SG) is the primary macrocyclic trichothecene produced by Stachybotrys chartarum, a fungus frequently associated with outbreaks of indoor air illness, little is known about the actual quantities of this mycotoxin in suspect or n
Autor:
Bruce Ganem, Donald J. Creighton, Erin Joseph, Heekyung Tak, Zhebo Ding, Diana S. Hamilton, Haibo Wang, Julie L. Eiseman
Publikováno v:
Journal of medicinal chemistry. 46(1)
The antitumor activity of 2-crotonyloxymethyl-2-cyclohexenone (COMC-6) is not the result of the GSH conjugate (GSMC-6) formed inside tumor cells, as the diethyl ester prodrug form of GSMC-6 displays little antitumor activity with B16 melanotic melano
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 49:1990-1992
The title compound, 3-phenyl-1-(2,4,5-trihydroxy-3,5-dimethyl-6-oxo-1,5-cyclohexadienyl)-1-propanone, was confirmed to be a dihydrochalcone containing a fully substituted cyclohexadienone ring. This ring has a flattened half-chair conformation, with
Publikováno v:
Biochemical and biophysical research communications. 226(3)
In our previous studies (Refs. 1 and 2), it was shown that protein tyrosine kinase (PTK) inhibitors, radicicol and herbimycin A, inhibit the expression of the mitogen-inducible cyclooxygenase (COX-2) and proinflammatory cytokines. Radicicol and herbi