Zobrazeno 1 - 10
of 904
pro vyhledávání: '"Heeke, A"'
Autor:
Lingzhi Hong, Sonia Patel, Leylah M. Drusbosky, Yuanyuan Xiong, Rongrong Chen, Ruixuan Geng, Simon Heeke, Monique Nilsson, Jia Wu, John V. Heymach, Yingyi Wang, Jianjun Zhang, Xiuning Le
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract ERBB2 (HER2) represents a newly recognized actionable oncogenic driver in non-small cell lung cancer (NSCLC), with approved targeted therapy available. Understanding the landscape of ERBB2 alterations and co-occurring mutations is essential
Externí odkaz:
https://doaj.org/article/7d1f2cdad9384d7bb4c05d844e0f4351
Autor:
Michael Mullin, James McClory, Winston Haynes, Justin Grace, Nathan Robertson, Gino van Heeke
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTThe development of bispecific antibodies that bind at least two different targets relies on bringing together multiple binding domains with different binding properties and biophysical characteristics to produce a drug-like therapeutic. These
Externí odkaz:
https://doaj.org/article/01baed59c39a4b3285f77233b47c5e3e
Autor:
Sheeba J. Sujit, Muhammad Aminu, Tatiana V. Karpinets, Pingjun Chen, Maliazurina B. Saad, Morteza Salehjahromi, John D. Boom, Mohamed Qayati, James M. George, Haley Allen, Mara B. Antonoff, Lingzhi Hong, Xin Hu, Simon Heeke, Hai T. Tran, Xiuning Le, Yasir Y. Elamin, Mehmet Altan, Natalie I. Vokes, Ajay Sheshadri, Julie Lin, Jianhua Zhang, Yang Lu, Carmen Behrens, Myrna C. B. Godoy, Carol C. Wu, Joe Y. Chang, Caroline Chung, David A. Jaffray, Ignacio I. Wistuba, J. Jack Lee, Ara A. Vaporciyan, Don L. Gibbons, John Heymach, Jianjun Zhang, Tina Cascone, Jia Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract While we recognize the prognostic importance of clinicopathological measures and circulating tumor DNA (ctDNA), the independent contribution of quantitative image markers to prognosis in non-small cell lung cancer (NSCLC) remains underexplor
Externí odkaz:
https://doaj.org/article/8ee2d864530b4ff5bcd6763fb81cd4af
Autor:
Heeke, Arielle L., Sha, Wei, Feldman, Rebecca, Fisher, Julie, Hadzikadic-Gusic, Lejla, Symanowski, James T., White, Richard L., Jr, Tan, Antoinette R.
Publikováno v:
In Clinical Breast Cancer October 2024 24(7):630-638
Autor:
Anna Solta, Büsra Ernhofer, Kristiina Boettiger, Zsolt Megyesfalvi, Simon Heeke, Mir Alireza Hoda, Christian Lang, Clemens Aigner, Fred R. Hirsch, Karin Schelch, Balazs Döme
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-25 (2024)
Abstract Current treatment guidelines refer to small cell lung cancer (SCLC), one of the deadliest human malignancies, as a homogeneous disease. Accordingly, SCLC therapy comprises chemoradiation with or without immunotherapy. Meanwhile, recent studi
Externí odkaz:
https://doaj.org/article/9e0908a3548240cd8b1b9b99d893d136
Autor:
Johanna Boettcher, Manuel Heinrich, Maria Boettche, Sebastian Burchert, Heide Glaesmer, Euphrosyne Gouzoulis-Mayfrank, Carina Heeke, Martina Hernek, Christine Knaevelsrud, Alexander Konnopka, Louisa Muntendorf, Hannah Nilles, Laura Nohr, Steffi Pohl, Sophia Paskuy, Isabelle Reinhardt, Susan Sierau, Nadine Stammel, Christina Wirz, Babette Renneberg, Birgit Wagner
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Refugee populations have an increased risk for mental disorders, such as depression, anxiety, and posttraumatic stress disorders. Comorbidity is common. At the same time, refugees face multiple barriers to accessing mental health
Externí odkaz:
https://doaj.org/article/82af96130fc84780932f8d9118a2dd06
Autor:
Annie Borch, Ibel Carri, Birkir Reynisson, Heli M. Garcia Alvarez, Kamilla K. Munk, Alessandro Montemurro, Nikolaj Pagh Kristensen, Siri A. Tvingsholm, Jeppe Sejerø Holm, Christina Heeke, Keith Henry Moss, Ulla Kring Hansen, Anna-Lisa Schaap-Johansen, Frederik Otzen Bagger, Vinicius Araujo Barbosa de Lima, Kristoffer S. Rohrberg, Samuel A. Funt, Marco Donia, Inge Marie Svane, Ulrik Lassen, Carolina Barra, Morten Nielsen, Sine Reker Hadrup
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMutation-derived neoantigens are critical targets for tumor rejection in cancer immunotherapy, and better tools for neoepitope identification and prediction are needed to improve neoepitope targeting strategies. Computational tools have ena
Externí odkaz:
https://doaj.org/article/0bbbca7628154c30a577b6a43214db8d
Autor:
Sehhoon Park, Tae Hee Hong, Soohyun Hwang, Simon Heeke, Carl M. Gay, Jiyeon Kim, Hyun-Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Jong Ho Cho, Yong Soo Choi, Jhingook Kim, Young Mog Shim, Hong Kwan Kim, Lauren Averett Byers, John V. Heymach, Yoon-La Choi, Se-Hoon Lee, Keunchil Park
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105062- (2024)
Summary: Background: Recent studies have reported the predictive and prognostic value of novel transcriptional factor-based molecular subtypes in small-cell lung cancer (SCLC). We conducted an in-depth analysis pairing multi-omics data with immunohis
Externí odkaz:
https://doaj.org/article/40a1e82c84034502bbbe4835972d5109
Autor:
Park, Sehhoon, Hong, Tae Hee, Hwang, Soohyun, Heeke, Simon, Gay, Carl M., Kim, Jiyeon, Jung, Hyun-Ae, Sun, Jong-Mu, Ahn, Jin Seok, Ahn, Myung-Ju, Cho, Jong Ho, Choi, Yong Soo, Kim, Jhingook, Shim, Young Mog, Kim, Hong Kwan, Byers, Lauren Averett, Heymach, John V., Choi, Yoon-La, Lee, Se-Hoon, Park, Keunchil
Publikováno v:
In eBioMedicine April 2024 102
Autor:
Heeke, Simon, Gay, Carl M., Estecio, Marcos R., Tran, Hai, Morris, Benjamin B., Zhang, Bingnan, Tang, Ximing, Raso, Maria Gabriela, Rocha, Pedro, Lai, Siqi, Arriola, Edurne, Hofman, Paul, Hofman, Veronique, Kopparapu, Prasad, Lovly, Christine M., Concannon, Kyle, De Sousa, Luana Guimaraes, Lewis, Whitney Elisabeth, Kondo, Kimie, Hu, Xin, Tanimoto, Azusa, Vokes, Natalie I., Nilsson, Monique B., Stewart, Allison, Jansen, Maarten, Horváth, Ildikó, Gaga, Mina, Panagoulias, Vasileios, Raviv, Yael, Frumkin, Danny, Wasserstrom, Adam, Shuali, Aharona, Schnabel, Catherine A., Xi, Yuanxin, Diao, Lixia, Wang, Qi, Zhang, Jianjun, Van Loo, Peter, Wang, Jing, Wistuba, Ignacio I., Byers, Lauren A., Heymach, John V.
Publikováno v:
In Cancer Cell 12 February 2024 42(2):225-237