Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Heejung Chun"'
Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease
Autor:
Suhyun Kim, Heejung Chun, Yunha Kim, Yeyun Kim, Uiyeol Park, Jiyeon Chu, Mridula Bhalla, Seung-Hye Choi, Ali Yousefian-Jazi, Sojung Kim, Seung Jae Hyeon, Seungchan Kim, Yeonseo Kim, Yeon Ha Ju, Seung Eun Lee, Hyunbeom Lee, Kyungeun Lee, Soo-Jin Oh, Eun Mi Hwang, Junghee Lee, C. Justin Lee, Hoon Ryu
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract Background Astrocytes, one of the most resilient cells in the brain, transform into reactive astrocytes in response to toxic proteins such as amyloid beta (Aβ) in Alzheimer’s disease (AD). However, reactive astrocyte-mediated non-cell aut
Externí odkaz:
https://doaj.org/article/10d1c6d648c04589a8cf3caf530fc135
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Pathological pain is caused by abnormal activity in the neural circuit that transmits nociceptive stimuli. Beyond homeostatic functions, astrocytes actively participate in regulating synaptic transmission as members of tripartite synapses. T
Externí odkaz:
https://doaj.org/article/fc45c964baac4fe7b6e143a37ce2634a
Autor:
Hyungju Park, Kyung-Seok Han, Jinsoo Seo, Jaekwang Lee, Shashank M. Dravid, Junsung Woo, Heejung Chun, Sukhee Cho, Jin Young Bae, Heeyoung An, Woohyun Koh, Bo-Eun Yoon, Rolando Berlinguer-Palmini, Guido Mannaioni, Stephen F. Traynelis, Yong Chul Bae, Se-Young Choi, C. Justin Lee
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/244da3947f774b08a6f188c2e50e5bf9
Autor:
Min-Ho Nam, Kyung-Seok Han, Jaekwang Lee, Woojin Won, Wuhyun Koh, Jin Young Bae, Junsung Woo, Jayoung Kim, Elliot Kwong, Tae-Yong Choi, Heejung Chun, Seung Eun Lee, Sang-Bum Kim, Ki Duk Park, Se-Young Choi, Yong Chul Bae, C. Justin Lee
Publikováno v:
Cell Reports, Vol 28, Iss 5, Pp 1154-1166.e5 (2019)
Summary: The underlying mechanisms of how positive emotional valence (e.g., pleasure) causes preference of an associated context is poorly understood. Here, we show that activation of astrocytic μ-opioid receptor (MOR) drives conditioned place prefe
Externí odkaz:
https://doaj.org/article/bad3616ea2ef44b1b0a2ee9256c9f284
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Alzheimer's disease (AD) is an irreversible neurodegenerative illness and the exact etiology of the disease remains unknown. It is characterized by long preclinical and prodromal phases with pathological features including an accumulation of amyloid-
Externí odkaz:
https://doaj.org/article/ba9952d67445422ba3e3c4e84bbebe93
Autor:
Heejung Chun
Publikováno v:
KOREAN JOURNAL OF YOUTH STUDIES. 30:473-495
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1ba1ba2e50747b4590b8653d5408174
https://doi.org/10.21509/kjys.2023.2.30.02.473
https://doi.org/10.21509/kjys.2023.2.30.02.473
Publikováno v:
Journal of Child and Family Studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::114f4feb0a90faf8810681fcc923577f
https://doi.org/10.1007/s10826-022-02523-7
https://doi.org/10.1007/s10826-022-02523-7
Autor:
Yulong Li, C. Justin Lee, Heejung Chun, Jinhyeong Joo, Hyun Soo Shim, Jaekwang Lee, Junsung Woo, Jinpyo Hong, Hyunji Kang, Hoon Ryu, Ye Eun Chun, Mingu Gordon Park, Sunpil Kim, Mijeong Park, Soo Jin Oh, Jiesi Feng, Moonsun Sa, Wuhyun Koh, Seung Eun Lee, Jeiwon Cho
Publikováno v:
Biological Psychiatry. 91:740-752
Background NMDAR hypofunction has been implicated in several psychiatric disorders with an impairment of cognitive flexibility. However, the molecular mechanism of how NMDAR hypofunction with decreased NMDAR tone causes the impairment of cognitive fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8247a19021270df564830d2622b1132
https://doi.org/10.1016/j.biopsych.2021.10.012
https://doi.org/10.1016/j.biopsych.2021.10.012
Autor:
Heejung Chun
Publikováno v:
Korean Association For Learner-Centered Curriculum And Instruction. 22:509-525
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e230b147693fa531b944f2842e25520
https://doi.org/10.22251/jlcci.2022.22.3.509
https://doi.org/10.22251/jlcci.2022.22.3.509
Autor:
Jingu Lee, Joon‐Goon Kim, Sujung Hong, Young Seo Kim, Soyeon Ahn, Ryul Kim, Heejung Chun, Ki Duk Park, Yong Jeong, Dong‐Eog Kim, C. Justin Lee, Taeyun Ku, Pilhan Kim
Publikováno v:
Glia. 70:975-988
Cerebral microinfarct increases the risk of dementia. But how microscopic cerebrovascular disruption affects the brain tissue in cellular-level are mostly unknown. Herein, with a longitudinal intravital imaging, we serially visualized in vivo dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f02f22aa7563943c83367ad8f73063
https://doi.org/10.1002/glia.24151
https://doi.org/10.1002/glia.24151