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Autor:
Lee S. Rosen, Priti S. Hegde, Oliva Hwang, Jessica Li, Louie Naumovski, Mahrukh Huseni, Tanya Smyczek, Pamela N. Munster, Michael S. Gordon, Weilan Ye, Heejo Baek, Junko Aimi
Publikováno v:
Cancer Research. 71:3284-3284
In this study we report the use of pharmacodynamic (PD) biomarkers to guide the clinical development of a novel antibody targeting epidermal growth factor-like domain 7 (EGFL7). EGFL7 is a secreted protein produced by endothelial cells of nascent blo