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Akademický článek

Screening and Isolation of a Novel Polyene-Producing Streptomyces Strain Inhibiting Phytopathogenic Fungi in the Soil Environment

Autor: Heung-Soon Park, Hee-Ju Nah, Seung-Hoon Kang, Si-Sun Choi, Eung-Soo Kim

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)

Microbial-based eco-friendly biological substances are needed to protect crops from phytopathogenic fungi and replace toxic chemical fungicides that cause serious environmental issues. This study screened for soil antifungal Streptomyces strains, whi

Externí odkaz: https://doaj.org/article/2f8464b4143d49a1871fc5676a1daf27

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Akademický článek

Stimulated Biosynthesis of an C10-Deoxy Heptaene NPP B2 via Regulatory Genes Overexpression in Pseudonocardia autotrophica

Autor: Heung-Soon Park, Hye-Jin Kim, Chi-Young Han, Hee-Ju Nah, Si-Sun Choi, Eung-Soo Kim

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Polyene macrolides, such as nystatin A1, amphotericin B, and NPP A1, belong to a large family of valuable antifungal polyketide compounds that are typically produced by soil actinomycetes. Previously, NPP B1, a novel NPP A1 derivative harboring a hep

Externí odkaz: https://doaj.org/article/20673cf0fd3642bbac5533740be42601

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Akademický článek

Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system

Autor: Hye-rim Pyeon, Hee-Ju Nah, Seung-Hoon Kang, Si-Sun Choi, Eung-Soo Kim

Publikováno v: Microbial Cell Factories, Vol 16, Iss 1, Pp 1-9 (2017)

Abstract Background Heterologous expression of biosynthetic gene clusters of natural microbial products has become an essential strategy for titer improvement and pathway engineering of various potentially-valuable natural products. A Streptomyces ar

Externí odkaz: https://doaj.org/article/679ded61601546ce80134caf3045e77d

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Streptomyces BAC Cloning of a Large-Sized Biosynthetic Gene Cluster of NPP B1, a Potential SARS-CoV-2 RdRp Inhibitor

Autor: Ji-Hee Park, Heung-Soon Park, Hee-Ju Nah, Seung-Hoon Kang, Si-Sun Choi, Eung-Soo Kim

Publikováno v: Journal of Microbiology and Biotechnology. 32:911-917

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b9019cd8817279ca7a2d97ecf92667c
https://doi.org/10.4014/jmb.2205.05036

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Akademický článek

WblA, a global regulator of antibiotic biosynthesis in Streptomyces.

Autor: Hee-Ju Nah¹, Jihee Park¹, Sisun Choi¹, Eung-Soo Kim¹ eungsoo@inha.ac.kr

Publikováno v: Journal of Industrial Microbiology & Biotechnology. Apr2021, Vol. 48 Issue 3/4, p1-8. 8p.

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Heterologous Expression of Daptomycin Biosynthetic Gene Cluster Via Streptomyces Artificial Chromosome Vector System

Autor: Si-Sun Choi, Eung-Soo Kim, Hee-Ju Nah, Seung-Hee Choi

Publikováno v: Journal of Microbiology and Biotechnology. 29:1931-1937

The heterologous expression of the Streptomyces natural product (NP) biosynthetic gene cluster (BGC) has become an attractive strategy for the activation, titer improvement, and refactoring of valuable and cryptic NP BGCs. Previously, a Streptomyces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe730c6e8e2f5e3654c761214575682a
https://doi.org/10.4014/jmb.1909.09022

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WblA, a global regulator of antibiotic biosynthesis in Streptomyces

Autor: Eung-Soo Kim, Si-Sun Choi, Hee-Ju Nah, Jihee Park

Publikováno v: Journal of industrial microbiologybiotechnology. 48(3-4)

Streptomyces species are soil-dwelling bacteria that produce vast numbers of pharmaceutically valuable secondary metabolites (SMs), such as antibiotics, immunosuppressants, antiviral, and anticancer drugs. On the other hand, the biosynthesis of most

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e85cb3745dc4b7d17a5103918acba5
https://pubmed.ncbi.nlm.nih.gov/33928363

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Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system

Autor: Si-Sun Choi, Seung-Hoon Kang, Hee-Ju Nah, Eung-Soo Kim, Hye-rim Pyeon

Publikováno v: Microbial Cell Factories, Vol 16, Iss 1, Pp 1-9 (2017)
Microbial Cell Factories
MICROBIAL CELL FACTORIES(16)

Background Heterologous expression of biosynthetic gene clusters of natural microbial products has become an essential strategy for titer improvement and pathway engineering of various potentially-valuable natural products. A Streptomyces artificial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f80d75d160842259d56ccff32314ffc
http://link.springer.com/article/10.1186/s12934-017-0708-7

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