Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hee-Doo Yoo"'
Autor:
Therasa Kim, He Yun Choi, Hyun-Seo Lee, Sung-Hoon Jung, Jae-Sook Ahn, Hyeoung-Joon Kim, Je-Jung Lee, Hee-Doo Yoo, Deok-Hwan Yang
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background A relatively high proportion of patients diagnosed with primary CNS lymphoma will experience recurrent disease, yet therapy options are limited in salvage therapy. This is the first study to evaluate a bendamustine-based combinati
Externí odkaz:
https://doaj.org/article/6c591a3ab41444d4bbcced82f66334aa
Publikováno v:
Drug Design, Development and Therapy. 13:1751-1761
Aim: Tramadol is widely used to treat acute, chronic, and neuropathic pain. Its primary active metabolite, O-desmethyltramadol (M1), is mainly responsible for its µ-opioid receptor-related analgesic effect. Tramadol is metabolized to M1 mainly by th
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 44:291-303
In this study, the population pharmacokinetic (PK) analysis of rebamipide (Reba) in healthy male Korean subjects was analyzed using the nonlinear mixed effects modeling method. The possible effects of physiological covariates and the multidrug resist
Autor:
Deok-Hwan Yang, Hyun-Seo Lee, Sung-Hoon Jung, Hee-Doo Yoo, Jae-Sook Ahn, Therasa Kim, He Yun Choi, Je-Jung Lee, Hyeoung-Joon Kim
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Background A relatively high proportion of patients diagnosed with primary CNS lymphoma will experience recurrent disease, yet therapy options are limited in salvage therapy. This is the first study to evaluate a bendamustine-based combination regime
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 44(6)
The objective of this study was to perform population pharmacokinetic (PK) analysis of gabapentin in healthy Korean subjects and to investigate the possible effect of genetic polymorphisms (1236C > T, 2677G > T/A, and 3435C > T) of ABCB1 gene on PK p
Publikováno v:
The AAPS Journal. 15:571-580
This study investigated the effects of genetic polymorphisms in organic cation transporter (OCT) genes, such as OCT1-3, OCTN1, MATE1, and MATE2-K, on metformin pharmacokinetics. Of particular interest was the influence of genetic polymorphisms as cov
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics. 39:329-341
This study estimated the population pharmacokinetics of risperidone and its active metabolite, 9-hydroxyrisperidone, according to genetic polymorphisms in the metabolizing enzyme (CYP2D6) and transporter (ABCB1) genes in healthy subjects. Eighty heal
Publikováno v:
British Journal of Pharmacology. 164:433-443
BACKGROUND AND PURPOSE The objective of this study was to investigate the combined influence of genetic polymorphisms in ABCB1 and CYP2D6 genes on risperidone pharmacokinetics. EXPERIMENTAL APPROACH Seventy-two healthy Korean volunteers receiving a s
Autor:
In-Ho Kwon, Min-Sun Kang, Sang-No Lee, Se-Mi Kim, Hyun-Ah Kang, Yong-Bok Lee, Hee-Doo Yoo, Dong-Jin Yoo
Publikováno v:
Journal of Pharmaceutical Investigation. 40:117-123
Ibudilast, 3-isobutyryl-2-isopropyrazolo[1,5-a]pyridine, is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE). It preferentially inhibits PDE 3A, PDE4, PDE10 and PDE11 as well as a number of the other PDE families, albeit to a les
Autor:
Seung-Rae Kang, In-Ho Kwon, Min-Sun Kang, Se-Mi Kim, Hyun-Ah Kang, Yong-Bok Lee, Sang-No Lee, Hee-Doo Yoo, Yoon-Gyoon Kim
Publikováno v:
Journal of Pharmaceutical Investigation. 40:109-115
【The purpose of the present study was to evaluate the bioequivalence of two choline alphoscerate soft capsules, Gliatilin soft capsule (Daewoong Pharmaceuticals Co., Ltd.) and Cholicerin soft capsule (Sam Chun Dang Pharm. Co., Ltd.), according to t