Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Hee Seok Kweon"'
Autor:
Minjae Kang, Min Jeong Kim, Dokyung Jeong, Hyung-Jun Lim, Ga-eun Go, Uidon Jeong, Eunyoung Moon, Hee-Seok Kweon, Nae-Gyu Kang, Seung Jin Hwang, Sung Hun Youn, Bo Kyoung Hwang, Doory Kim
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Bacterial extracellular vesicles (EVs) are pivotal mediators of intercellular communication and influence host cell biology, thereby contributing to the pathogenesis of infections. Despite their significance, the precise effects o
Externí odkaz:
https://doaj.org/article/d7dceeaed9c9429b938ee2e6907978bf
Autor:
Ga-Young Choi, In-Seo Lee, Eunyoung Moon, Hyosung Choi, A Reum Je, Ji-Ho Park, Hee-Seok Kweon
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117000- (2024)
Alzheimer’s disease (AD) is characterized by cognitive impairment, loss of learning and memory, and abnormal behaviors. Scopolamine (SCOP) is a non-selective antagonist of muscarinic acetylcholine receptors that exhibits the behavioral and molecula
Externí odkaz:
https://doaj.org/article/b61abdaf3ad44be190fa52f25af9e6c4
Publikováno v:
Applied Microscopy, Vol 54, Iss 1, Pp 1-3 (2024)
Abstract The neuroprotective effects of umbelliferone (UMB) were visualized in three-dimensional (3D) images on vesicle density changes of organotypic hippocampal slice tissues (OHSCs) induced by scopolamine by high voltage electron microscopy. Obser
Externí odkaz:
https://doaj.org/article/783e156fe1da48b3b0cafa5718b3a046
Autor:
Seung Han Son, Min Young Kim, Sungwoo Choi, Ji Sook Kim, Yong Sang Lee, Sangwon Lee, Yeon Ju Lee, Jin Youn Lee, Seol Eui Lee, Young Su Lim, Dae Hyun Ha, Eonju Oh, Young‐Bin Won, Chang‐Jun Ji, Mi Ae Park, Boram Kim, Kyu Tae Byun, Min Sung Chung, Jaemin Jeong, Dongho Choi, Eun Jung Baek, Eung‐Ho Cho, Sang‐Bum Kim, A. Reum Je, Hee‐Seok Kweon, Hyun Sook Park, Dongsun Park, June Sung Bae, Se Jin Jang, Chae‐Ok Yun, Ji Hyung Chae, Jin‐Won Lee, Su‐Jae Lee, Chan Gil Kim, Ho Chul Kang, Vladimir N. Uversky, Chul Geun Kim
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract Despite advances in precision oncology, cancer remains a global public health issue. In this report, proof‐of‐principle evidence is presented that a cell‐penetrable peptide (ACP52C) dissociates transcription factor CP2c complexes and i
Externí odkaz:
https://doaj.org/article/7df14abecef94bbd8fa5132f2475e583
Autor:
Jun Woo Park, Eun Jung Lee, Eunyoung Moon, Hong-Lim Kim, In-Beom Kim, Didier Hodzic, Namsuk Kim, Hee-Seok Kweon, Jin Woo Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Many homeodomain transcription factors are secreted and move to neighboring cells. Here, orthodenticle homeobox 2 is shown to be exported from the nucleus in a nuclear membrane, which buds off to then be degraded or secreted.
Externí odkaz:
https://doaj.org/article/7e909973f8674062b12557dcbf2f5832
Autor:
Dokyung Jeong, Min Jeong Kim, Yejin Park, Jinkyoung Chung, Hee-Seok Kweon, Nae-Gyu Kang, Seung Jin Hwang, Sung Hun Youn, Bo Kyoung Hwang, Doory Kim
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Recently, bacterial extracellular vesicles (EVs) have been considered to play crucial roles in various biological processes and have great potential for developing cancer therapeutics and biomedicine. However, studies on bacterial
Externí odkaz:
https://doaj.org/article/d88b9d2ee98e4220a85c42484077e450
Autor:
Juhyeon Son, Okkeun Jung, Jong Heon Kim, Kyu Sang Park, Hee-Seok Kweon, Nhung Thi Nguyen, Yu Jin Lee, Hansol Cha, Yejin Lee, Quangdon Tran, Yoona Seo, Jongsun Park, Jungwon Choi, Heesun Cheong, Sang Yeol Lee
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102628- (2023)
Mitochondrial methionyl-tRNA synthetase (MARS2) canonically mediates the formation of fMet-tRNAifMet for mitochondrial translation initiation. Mitochondrial calcium uniporter (MCU) is a major gate of Ca2+ flux from cytosol into the mitochondrial matr
Externí odkaz:
https://doaj.org/article/5bd482d4bba44bd6bbbecfedc52d4d2f
Autor:
Jeong-Yong Shin, Bina Lee, Sangwoo Ham, Ji Hun Kim, Hyojung Kim, Heejeong Kim, Min Gi Jo, Hye Jung Kim, Sang Won Park, Hee-Seok Kweon, Yong Jun Kim, Seung Pil Yun, Yunjong Lee
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113908- (2022)
The aggregation of aminoacyl transfer RNA synthetase complex-interacting multifunctional protein-2 (AIMP2) accelerates α-synuclein aggregation via direct interaction, leading to enhanced dopaminergic neurotoxicity in Parkinson’s disease (PD). Thus
Externí odkaz:
https://doaj.org/article/384194fc65bd47e6acd7a06f169bd83a
Autor:
Jiyoon Kim, Hyeyon Kim, Shin Hye Noh, Dong Geon Jang, Shi-Young Park, Dongkook Min, Hyunki Kim, Hee-Seok Kweon, Hoguen Kim, Sowon Aum, Sookyung Seo, Cheol Soo Choi, Hail Kim, Jae Woo Kim, Seok Jun Moon, Heon Yung Gee, Min Goo Lee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The physiological roles of the Golgi reassembly-stacking protein 55 (GRASP55/GORASP55) remain largely elusive. Here, the authors show that the Golgi-resident protein GRASP55 plays a crucial role in lipid homeostasis by regulating intestinal lipid upt
Externí odkaz:
https://doaj.org/article/cf1efe464e0048bcb1c2c89a7f1a6032
Autor:
Hye-Sook Han, Sang Gyune Kim, Young Seok Kim, Si-Hyong Jang, Yongmin Kwon, Dahee Choi, Tom Huh, Eunyoung Moon, Eunyong Ahn, Je Kyung Seong, Hee-Seok Kweon, Geum-Sook Hwang, Dae Ho Lee, Kae Won Cho, Seung-Hoi Koo
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101402- (2022)
Objective: Diet-induced obesity is often associated with nonalcoholic fatty liver disease (NAFLD), which instigates severe metabolic disorders, including cirrhosis, hepatocellular carcinoma, and type 2 diabetes. We have shown that hepatic depletion o
Externí odkaz:
https://doaj.org/article/7b787322d9f843c4ad7ec37dc28d4bb7