Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Hee Kyung Hong"'
Autor:
Hee Kyung Hong
Publikováno v:
Education Policy Analysis Archives, Vol 20, Iss 0 (2012)
The purpose of this study was to simultaneously examine relationships between teacher quality and instructional time and mathematics and science achievement of 8th grade cohorts in 18 advanced and developing economies. In addition, the study examined
Externí odkaz:
https://doaj.org/article/de5d901a679b4b538b00a1dac7207332
Autor:
Nina C. Lund, Yetunde Kayode, Melanie R. McReynolds, Deanna C. Clemmer, Hannah Hudson, Isabelle Clerc, Hee-Kyung Hong, Jason M. Brenchley, Joseph Bass, Richard T. D’Aquila, Harry E. Taylor
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
mTOR limits the activation of an inflammatory gene response in monocytes. Inhibitors of mTOR enhance NF-κB-driven transcription in LPS-stimulated monocytes while depleting NAD+ through effects on the salvage pathway.
Externí odkaz:
https://doaj.org/article/6764010621db4decbc08cfa607d9a1f7
Autor:
Daniel C. Levine, Hsin-Yu Kuo, Hee-Kyung Hong, Jonathan Cedernaes, Chelsea Hepler, Alexandra G. Wright, Meredith A. Sommars, Yumiko Kobayashi, Biliana Marcheva, Peng Gao, Olga R. Ilkayeva, Chiaki Omura, Kathryn M. Ramsey, Christopher B. Newgard, Grant D. Barish, Clara Bien Peek, Navdeep S. Chandel, Milan Mrksich, Joseph Bass
Publikováno v:
Nature Metabolism
In mammals, circadian rhythms are entrained to the light cycle and drive daily oscillations in levels of NAD+, a cosubstrate of the class III histone deacetylase sirtuin 1 (SIRT1) that associates with clock transcription factors. Although NAD+ also p
Autor:
Akihiko Taguchi, Biliana Marcheva, Gene W. Yeo, Emily C. Wheeler, Patrick E. MacDonald, Chiaki Omura, Marsha V. Newman, Yumiko Kobayashi, Eugene Wyatt, Mark Perelis, Archana Shankar, Jocelyn E. Manning Fox, Elizabeth M. McNally, Hee Kyung Hong, Benjamin J. Weidemann, Haopeng Lin, Kathryn Moynihan Ramsey, Joseph Bass
Publikováno v:
Genes Dev
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through molecular programs that remain incompletely understood. Here, we reveal rhythmic genome-wide alternative splicing (AS) of pre-
Autor:
Wan-seop Kim, Hee-kyung Hong
Publikováno v:
The Korean Society of Culture and Convergence. 42:253-283
Autor:
Kazuhiro Shimomura, Vivek Kumar, Nobuya Koike, Tae-Kyung Kim, Jason Chong, Ethan D Buhr, Andrew R Whiteley, Sharon S Low, Chiaki Omura, Deborah Fenner, Joseph R Owens, Marc Richards, Seung-Hee Yoo, Hee-Kyung Hong, Martha H Vitaterna, Joseph Bass, Mathew T Pletcher, Tim Wiltshire, John Hogenesch, Phillip L Lowrey, Joseph S Takahashi
Publikováno v:
eLife, Vol 2 (2013)
Genetic and molecular approaches have been critical for elucidating the mechanism of the mammalian circadian clock. Here, we demonstrate that the ClockΔ19 mutant behavioral phenotype is significantly modified by mouse strain genetic background. We m
Externí odkaz:
https://doaj.org/article/d769ffe1cd9845f0911f69fd98294374
Publikováno v:
International Journal of Oral Biology. 43:43-51
Autor:
Benjamin J. Weidemann, Chiaki Omura, Rosemary Braun, Choogon Lee, Clara Bien Peek, Alison H. Affinati, Joseph Bass, Daniel C. Levine, Mark S. Schmidt, Kathryn Moynihan Ramsey, Jonathan Cedernaes, Charles Brenner, Hee Kyung Hong
Publikováno v:
Mol Cell
Disrupted sleep-wake and molecular circadian rhythms are a feature of aging associated with metabolic disease and reduced levels of NAD(+), yet whether changes in nucleotide metabolism control circadian behavioral and genomic rhythms remains unknown.
Autor:
Hee Kyung Hong, Katherine J. Motyl, Carla B. Green, Jeremy J. Stubblefield, Joseph S. Takahashi, Anyonya R. Guntur, Sheila Bornstein, Li Tian, Phuong T. Le, Clifford J. Rosen
Publikováno v:
J Cell Physiol
Nocturnin (NOCT) belongs to the Mg2+ dependent Exonucleases, Endonucleases, Phosphatase (EEP) family of enzymes that exhibit various functions in vitro and in vivo. NOCT is known to function as a deadenylase, cleaving poly-A tails from mRNA (messenge
Autor:
Hee Kyung Hong, Ima Samba, Michael Rosbash, Daniel C. Levine, Da Hyun Lee, Bridget C. Lear, Joseph Bass, Elzbieta Kula-Eversole, Ravi Allada, Evrim Yildirim
Publikováno v:
Curr Biol
The timing of behavior under natural light-dark conditions is a function of circadian clocks and photic input pathways. Yet a mechanistic understanding of how these pathways collaborate in animals is lacking. Here we demonstrate in Drosophila that th