Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hee Hoon Kim"'
Autor:
Hee-Hoon Kim, Young-Ri Shim, Ha Neul Kim, Keungmo Yang, Tom Ryu, Kyurae Kim, Sung Eun Choi, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Hyemi Shin, Jae Myoung Suh, Youngae Jung, Geum-Sook Hwang, Won Kim, Seok-Hwan Kim, Hyuk Soo Eun, Je Kyung Seong, Won-Il Jeong
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112636- (2023)
Summary: Obesity-mediated hypoxic stress underlies inflammation, including interferon (IFN)-γ production by natural killer (NK) cells in white adipose tissue. However, the effects of obesity on NK cell IFN-γ production remain obscure. Here, we show
Externí odkaz:
https://doaj.org/article/d0d7fa527d414e97b49ac647aa5bdc1a
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The continuous rise in the prevalence of nonalcoholic fatty liver disease (NAFLD) is emerging as a global health issue. Although the protective effects of N-acetylcysteine (NAC), an antioxidant, against various diseases have been report
Externí odkaz:
https://doaj.org/article/2f77c20a8b084a14b94147ef5caebad6
Autor:
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Tolulope Esther Falana, Jae-Kwang Yoo, So-Hee Ahn, Minhye Park, Hyangmi Seo, Chulhee Choi, Won-Il Jeong
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 636 (2023)
Activation of Kupffer cells (KCs) by gut-derived lipopolysaccharide (LPS) instigates nuclear factor-κB (NF-κB)-mediated inflammatory responses in alcohol-associated liver diseases (ALD). Here, we utilized a novel optogenetically engineered exosome
Externí odkaz:
https://doaj.org/article/bfa0bbfbf3c44aae8bfe20f78b1af6fb
Autor:
Myung-Ho Kim, Hee-Hoon Kim, Jong-Min Jeong, Young-Ri Shim, Jun-Hee Lee, Ye Eun Kim, Tom Ryu, Keungmo Yang, Kyu-Rae Kim, Byeong-Min Jeon, Sun Chang Kim, Jae-Kwang Jung, Jae-Kap Choi, Young-Sun Lee, Jin-Seok Byun, Won-Il Jeong
Publikováno v:
Journal of Ginseng Research, Vol 44, Iss 6, Pp 815-822 (2020)
Background: Recently, beneficial roles of ginsenoside F2 (GF2), a minor constituent of Panax ginseng, have been demonstrated in diverse inflammatory diseases. However, its roles in alcoholic liver inflammation and injury have not been clearly underst
Externí odkaz:
https://doaj.org/article/0722f267c7d34bc8b469e06aa6e49f05
Autor:
Sun Mi Hong, A-Yeon Lee, Sung-Min Hwang, Yu-Jin Ha, Moo-Jin Kim, Seongki Min, Won Hwang, Gyesoon Yoon, So Mee Kwon, Hyun Goo Woo, Hee-Hoon Kim, Won-Il Jeong, Han-Ming Shen, Sin-Hyeog Im, Dakeun Lee, You-Sun Kim
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102237- (2022)
Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD+) salvage pathway and plays a crucial role in the maintenance of the NAD+ pool during inflammation. Considering that macrophages
Externí odkaz:
https://doaj.org/article/4f84bec6185c4c0ca0541ee759f35cbb
Publikováno v:
Clinical and Molecular Hepatology, Vol 26, Iss 4, Pp 697-704 (2020)
Chronic alcohol consumption induces the development of alcoholic steatosis in the liver, which is one of the most widespread liver diseases worldwide. During general alcohol metabolism, hepatocytes generate mitochondria- and cytochrome P450 2E1 (CYP2
Externí odkaz:
https://doaj.org/article/a8bc5aa90b18448490f53ffa2dddca75
Publikováno v:
Nutrients, Vol 15, Iss 3, p 721 (2023)
Although tremendous research has reported the protective effects of natural compounds in nonalcoholic fatty liver disease (NAFLD), there is still no approved drug. This study aimed to examine the efficacy of Panax ginseng in NAFLD in preclinical stud
Externí odkaz:
https://doaj.org/article/cdf42b1080b647afa099727432fe2dd4
Autor:
Hee-Hoon Kim, Young-Ri Shim, Sung Eun Choi, Myung-Ho Kim, Giljae Lee, Hyun Ju You, Won-Mook Choi, Keungmo Yang, Tom Ryu, Kyurae Kim, Min Jeong Kim, Chaerin Woo, Katherine Po Sin Chung, Song Hwa Hong, Hyuk Soo Eun, Seok-Hwan Kim, GwangPyo Ko, Jong-Eun Park, Bin Gao, Won Kim, Won-Il Jeong
Publikováno v:
Experimental & Molecular Medicine. 55:158-170
Chronic alcohol consumption often induces hepatic steatosis but rarely causes severe inflammation in Kupffer cells (KCs) despite the increased hepatic influx of lipopolysaccharide (LPS), suggesting the presence of a veiled tolerance mechanism. In add
Autor:
Young-Sun Lee, Myung-Ho Kim, Hyon-Seung Yi, So Yeon Kim, Hee-Hoon Kim, Ji Hoon Kim, Jong Eun Yeon, Kwan Soo Byun, Jin-Seok Byun, Won-Il Jeong
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The expression of chemokine receptor CX3CR1 is related to migration and signaling in cells of the monocyte-macrophage lineage. The precise roles of CX3CR1 in the liver have been investigated but not clearly elucidated. Here, we investigated
Externí odkaz:
https://doaj.org/article/bd9bdcd8b9be49999ee286a46066b5f3
Publikováno v:
Methods in Molecular Biology ISBN: 9781071632062
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c87e4c8b46ddf12180a536a7196bcab9
https://doi.org/10.1007/978-1-0716-3207-9_7
https://doi.org/10.1007/978-1-0716-3207-9_7