Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Hee Cheol, Cho"'
Autor:
Parvin Forghani, Aysha Rashid, Lawrence C. Armand, David Wolfson, Rui Liu, Hee Cheol Cho, Joshua T. Maxwell, Hanjoong Jo, Khalid Salaita, Chunhui Xu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) possess tremendous potential for basic research and translational application. However, these cells structurally and functionally resemble fetal cardiomyocytes, whi
Externí odkaz:
https://doaj.org/article/3296641540fe46919673509caadadabf
Autor:
Dong Li, Lawrence C. Armand, Fangxu Sun, Hyun Hwang, David Wolfson, Antonio Rampoldi, Rui Liu, Parvin Forghani, Xin Hu, Wen-Mei Yu, Cheng-Kui Qu, Dean P. Jones, Ronghu Wu, Hee Cheol Cho, Joshua T. Maxwell, Chunhui Xu
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Background Cardiac pathological outcome of metabolic remodeling is difficult to model using cardiomyocytes derived from human-induced pluripotent stem cells (hiPSC-CMs) due to low metabolic maturation. Methods hiPSC-CM spheres were treated w
Externí odkaz:
https://doaj.org/article/562803dacdbb45ed92a888443f4bfd75
Autor:
Ilija Uzelac, Christopher J. Crowley, Shahriar Iravanian, Tae Yun Kim, Hee Cheol Cho, Flavio H. Fenton
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Most cardiac arrhythmias at the whole heart level result from alteration of cell membrane ionic channels and intracellular calcium concentration ([Ca2+]i) cycling with emerging spatiotemporal behavior through tissue-level coupling. For example, dynam
Externí odkaz:
https://doaj.org/article/ab7e2c2b7d814f609e0b9363006f28bf
Autor:
Jin-mo Gu, Sandra I. Grijalva, Natasha Fernandez, Elizabeth Kim, D. Brian Foster, Hee Cheol Cho
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 9, Pp 1-12 (2019)
Heart health: understanding pacemaker cells The heart’s pacemaker cells contain mitochondria that are smaller than average and require less energy than other heart cells, properties that help make them naturally resilient to stress. Cardiac pacemak
Externí odkaz:
https://doaj.org/article/41ab80b3ac45403e87c4103db9c1529c
Autor:
D. Brian Foster, Jin-mo Gu, Elizabeth H. Kim, David W. Wolfson, Robert O’Meally, Robert N. Cole, Hee Cheol Cho
Publikováno v:
Journal of Proteome Research. 21:2277-2292
Previously, we reported that heterologous expression of an embryonic transcription factor, Tbx18, reprograms ventricular cardiomyocytes into induced pacemaker cells (Tbx18-iPMs), though the key pathways are unknown. Here, we have used a tandem mass t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638d4d095a879972dbf30a3d1b792a1c
https://doi.org/10.1021/acs.jproteome.2c00133
https://doi.org/10.1021/acs.jproteome.2c00133
Autor:
Hyun Kook, Hee Cheol Cho
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 12, Pp 1-2 (2019)
Externí odkaz:
https://doaj.org/article/56a6300e613f46e1b2398b9641f88b7b
Autor:
Sandra I. Grijalva, Jin‐mo Gu, Jun Li, Natasha Fernandez, Jinqi Fan, Jung Hoon Sung, Seung Yup Lee, Conner Herndon, Erin M. Buckley, Sung‐Jin Park, Flavio H. Fenton, Hee Cheol Cho
Publikováno v:
Advanced Science, Vol 6, Iss 22, Pp n/a-n/a (2019)
Abstract Every heartbeat originates from a tiny tissue in the heart called the sinoatrial node (SAN). The SAN harbors only ≈10 000 cardiac pacemaker cells, initiating an electrical impulse that captures the entire heart, consisting of billions of c
Externí odkaz:
https://doaj.org/article/087002c9464344d5ae7d42d4f4dc2991
Autor:
Yun‐Soung Kim, Musa Mahmood, Yongkuk Lee, Nam Kyun Kim, Shinjae Kwon, Robert Herbert, Donghyun Kim, Hee Cheol Cho, Woon‐Hong Yeo
Publikováno v:
Advanced Science, Vol 6, Iss 17, Pp n/a-n/a (2019)
Abstract Commercially available health monitors rely on rigid electronic housing coupled with aggressive adhesives and conductive gels, causing discomfort and inducing skin damage. Also, research‐level skin‐wearable devices, while excelling in so
Externí odkaz:
https://doaj.org/article/0f99d10c45c540949e656ac003e1f232
Autor:
Vittoria Ionta, Wenbin Liang, Elizabeth H. Kim, Reza Rafie, Alessandro Giacomello, Eduardo Marbán, Hee Cheol Cho
Publikováno v:
Stem Cell Reports, Vol 4, Iss 1, Pp 129-142 (2015)
Summary: When pluripotency factors are removed, embryonic stem cells (ESCs) undergo spontaneous differentiation, which, among other lineages, also gives rise to cardiac sublineages, including chamber cardiomyocytes and pacemaker cells. Such heterogen
Externí odkaz:
https://doaj.org/article/69244a3e31c240a4bbe6bf6f38ab7727
Autor:
Hong Yi, Min Goo Lee, Sangsung Kim, Yoshiaki Tanaka, Hun-Jun Park, Kyuwon Cho, Young Sup Yoon, Patrick Tae Joon Hwang, Mark A. Sussman, Seongho Bae, Jaeyeaon Cho, Ho-Wook Jun, Richard P. Harvey, In-Hyun Park, Hee Cheol Cho, Eric Shin, Rebecca D. Levit, Ji Woong Han, Woongchan Rah, Jae kyung Jung, Hyein Lee, Sang Wook Lee, Nam Kyun Kim, Dong Hoon Shin
Publikováno v:
Nat Biomed Eng
Fibroblasts can be directly reprogrammed into cardiomyocytes, endothelial cells or smooth muscle cells. Here, we report the reprogramming of mouse tail-tip fibroblasts simultaneously into cells resembling these three cell types via the microRNA-mimic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb248ac5d4805ad64286697491fef95
https://doi.org/10.1038/s41551-021-00783-0
https://doi.org/10.1038/s41551-021-00783-0