Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hee‐Young Jeon"'
Autor:
Xun Jin, Hye-Min Jeon, Xiong Jin, Eun-Jung Kim, Jinlong Yin, Hee-Young Jeon, Young-Woo Sohn, Se-Yeong Oh, Jun-Kyum Kim, Sung-Hak Kim, Ji-Eun Jung, Sungwook Kwak, Kai-Fu Tang, Yunsheng Xu, Jeremy N. Rich, Hyunggee Kim
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1629-1641 (2016)
Inhibitor of differentiation 1 (ID1) is highly expressed in glioblastoma stem cells (GSCs). However, the regulatory mechanism responsible for its role in GSCs is poorly understood. Here, we report that ID1 activates GSC proliferation, self-renewal, a
Externí odkaz:
https://doaj.org/article/6e6373a1f43d4a54ab2df7a1746c7577
Publikováno v:
Tumor Biology, Vol 39 (2017)
Resistance to conventional therapies and frequent recurrence are the major obstacles to the treatment of high-grade gliomas, including glioblastoma. Thus, the development of new therapeutic strategies to overcome these obstacles is necessary to impro
Externí odkaz:
https://doaj.org/article/b339cf837a7143509706fe5185fad07c
Autor:
Pornour, Majid, Hee-Young Jeon, Hyunju Ryu, Khadka, Sudeep, Rui Xu, Hegang Chen, Hussain, Arif, Hung-Ming Lam, Zhihao Zhuang, Htoo Zarni Oo, Gleave, Martin, Xuesen Dong, Qianben Wang, Barbieri, Christopher, Jianfei Qi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/30/2024, Vol. 121 Issue 31, p1-12, 258p
Autor:
Hee-Young Jeon, Majid Pornour, Hyunju Ryu, Sudeep Khadka, Rui Xu, Jihyun Jang, Deqiang Li, Hegang Chen, Arif Hussain, Ladan Fazli, Martin Gleave, Xuesen Dong, Furong Huang, Qianben Wang, Christopher Barbieri, Jianfei Qi
Publikováno v:
Nucleic Acids Research. 51:2655-2670
Overexpression of androgen receptor (AR) is the primary cause of castration-resistant prostate cancer, although mechanisms upregulating AR transcription in this context are not well understood. Our RNA-seq studies revealed that SMAD3 knockdown decrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55c29b59bb5e567c696cafddbd1a97d2
https://doi.org/10.1093/nar/gkad043
https://doi.org/10.1093/nar/gkad043
Autor:
Hyunggee Kim, Jeremy N. Rich, Jinlong Yin, Seon Yong Lee, Jun-Kyum Kim, Eun-Jung Kim, Hee-Young Jeon, Deobrat Dixit, Leo J.Y. Kim, Xun Jin, Xiong Jin
Supplementary figures 1-7, supplementary tables 1-4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c14de81a6e08a7937ed63edc7d4254b
https://doi.org/10.1158/1078-0432.22467240.v1
https://doi.org/10.1158/1078-0432.22467240.v1
Autor:
Hyunggee Kim, Jeremy N. Rich, Jinlong Yin, Seon Yong Lee, Jun-Kyum Kim, Eun-Jung Kim, Hee-Young Jeon, Deobrat Dixit, Leo J.Y. Kim, Xun Jin, Xiong Jin
Purpose: Normal stem cells tightly control self-renewal and differentiation during development, but their neoplastic counterparts, cancer stem cells (CSCs), sustain tumorigenicity both through aberrant activation of stemness and evasion of differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3db1153c469a143e5203ca747ac9a9
https://doi.org/10.1158/1078-0432.c.6526584.v1
https://doi.org/10.1158/1078-0432.c.6526584.v1
Autor:
Hee-Young Jeon, Majid Pornour, Hyunju Ryu, Sudeep Khadka, Rui Xu, Jihyun Jang, Deqiang Li, Hegang Chen, Arif Hussain, Ladan Fazli, Martin Gleave, Xuesen Dong, Qianben Wang, Christopher Barbieri, Jianfei Qi
Publikováno v:
Cancer Research. 83:1454-1454
Overexpression of the androgen receptor (AR) is the primary cause of development of castration-resistant prostate cancer (CRPC), although mechanisms upregulating AR transcription in this context are not well understood. Our RNA-seq analysis revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b9b9dfdc62176f3286ee5326693f6d
https://doi.org/10.1158/1538-7445.am2023-1454
https://doi.org/10.1158/1538-7445.am2023-1454
Autor:
Kiyoung Eun, Seon‐Ung Hwang, Mirae Kim, Junchul David Yoon, Eunhye Kim, Hyerin Choi, Gahye Kim, Hee‐Young Jeon, Jun‐Kyum Kim, Jung Yun Kim, Nayoung Hong, Min‐Gi Park, Junseok Jang, Hyeon Ju Jeong, Sung Jin Kim, Bong‐Woo Ko, Sang Chul Lee, Hyunggee Kim, Sang‐Hwan Hyun
Publikováno v:
Biotechnology journalREFERENCES. 17(7)
Alternative cancer models that are close to humans are required to create more valuable preclinical results during oncology studies. Here, a new onco-pig model via developing a CRISPR-Cas9-based Conditional Polycistronic gene expression Cassette (CRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf81efe23dcdc2035ce72a6b0c52362
https://pubmed.ncbi.nlm.nih.gov/35233982
https://pubmed.ncbi.nlm.nih.gov/35233982
Publikováno v:
Mol Carcinog
JMJD1A (also called lysine demethylase 3A [KDM3A]) belongs to the Jumonji C family of histone demethylases. It specifically removes the repressive mono- or di-methyl marks from histone H3 at lysine 9 and thus contributes to the activation of gene tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6657ebefc75f6dba564ee556b2196bc
https://europepmc.org/articles/PMC8930527/
https://europepmc.org/articles/PMC8930527/
Autor:
Se Hoon Kim, Xiong Jin, Hyunggee Kim, Chang Yong Choi, Seok Won Ham, Hee Young Jeon, Xun Jin, Taehoon Chun, Seon Yong Lee, Yong Jae Shin, Do-Hyun Nam, Jason K. Sa, Jun Kyum Kim
Publikováno v:
Cell Death & Differentiation. 26:2139-2156
Most glioblastomas frequently recur at sites of radiotherapy, but it is unclear if changes in the tumor microenvironment due to radiotherapy influence glioblastoma recurrence. Here, we demonstrate that radiation-induced senescent glioblastoma cells e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab0f3cf9abb739a03b7579be116b102c
https://doi.org/10.1038/s41418-019-0282-0
https://doi.org/10.1038/s41418-019-0282-0