Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hedwin Kitdorlang Dkhar"'
Autor:
Ana Beatriz Enriquez, Jonathan Kevin Sia, Hedwin Kitdorlang Dkhar, Shu Ling Goh, Melanie Quezada, Kristina Larrieux Stallings, Jyothi Rengarajan
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104305- (2022)
Summary: Early Th17 responses are necessary to provide protection against Mycobacterium tuberculosis (Mtb). Mtb impedes Th17 polarization by restricting CD40 co-stimulatory pathway on dendritic cells (DCs). We previously demonstrated that engaging CD
Externí odkaz:
https://doaj.org/article/f7533561f8714bf38b651afe3f6a81f7
Autor:
Sandeep Dave, Ravikanth Nanduri, Hedwin Kitdorlang Dkhar, Ella Bhagyaraj, Alka Rao, Pawan Gupta
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100862 (2014)
Uncontrolled adipogenesis and adipocyte proliferation have been connected to human comorbidities. Retinoic acid (RA) is known to inhibit adipocyte differentiation, however the underlying mechanisms have not been adequately understood. This study repo
Externí odkaz:
https://doaj.org/article/478cc0a1fec0437796460122d78b74e7
Autor:
Pawan Gupta, Hedwin Kitdorlang Dkhar, Rakesh Kumar, Rashi Kalra, Drishti Tiwari, Anshu Bhardwaj, Ella Bhagyaraj
Publikováno v:
International Reviews of Immunology. 42:43-70
Introduction Despite new approaches in the diagnosis and treatment of tuberculosis (TB), it continues to be a major health burden. Several immunotherapies that potentiate the immune response have come up as adjuncts to drug therapies against drug res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52355fb9812052ea1ccfa9ddcf6a49d2
https://doi.org/10.1080/08830185.2021.1990277
https://doi.org/10.1080/08830185.2021.1990277
Autor:
Rashi, Kalra, Drishti, Tiwari, Hedwin Kitdorlang, Dkhar, Ella, Bhagyaraj, Rakesh, Kumar, Anshu, Bhardwaj, Pawan, Gupta
Publikováno v:
International reviews of immunology. 42(1)
Despite new approaches in the diagnosis and treatment of tuberculosis (TB), it continues to be a major health burden. Several immunotherapies that potentiate the immune response have come up as adjuncts to drug therapies against drug resistant TB str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7089cfc24a46c1077d51b692e2c0af54
https://pubmed.ncbi.nlm.nih.gov/34678117
https://pubmed.ncbi.nlm.nih.gov/34678117
Autor:
Melanie Quezada, Jonathan Kevin Sia, Shu Ling Goh, Hedwin Kitdorlang Dkhar, Ana Beatriz Enriquez, Jyothi Rengarajan
Publikováno v:
SSRN Electronic Journal.
Early Th17 responses are necessary to provide protection against Mycobacterium tuberculosis (Mtb). However, we previously demonstrated that Mtb restricts Th17 polarization and that engaging the CD40 costimulatory pathway on dendritic cells (DCs) enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::633ba48a35a190d70e47366e0127e054
https://doi.org/10.2139/ssrn.3904347
https://doi.org/10.2139/ssrn.3904347
Autor:
Hedwin Kitdorlang Dkhar, Casey Vantucci, Ana Beatriz Enriquez, Chris Ibegbu, Shivani Vyas, Nicole Alexis Woods, Khanyisile Kgoadi, Shu Ling Goh, Krishnendu Roy, Jyothi Rengarajan
Publikováno v:
The Journal of Immunology. 208:116.10-116.10
The bacterial pathogen Mycobacterium tuberculosis (Mtb) successfully evades host innate immune responses to cause tuberculosis (TB) disease. Recent studies showed that myeloid-derived suppressor cells (MDSCs) are recruited to the lung after Mtb infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c429e9683135a90b2807faba2df5e2db
https://doi.org/10.4049/jimmunol.208.supp.116.10
https://doi.org/10.4049/jimmunol.208.supp.116.10
Autor:
Nancy Ahuja, Ashok K. Janmeja, Hedwin Kitdorlang Dkhar, Ankita Saini, Rashi Kalra, Ravikanth Nanduri, Drishti Tiwari, Ella Bhagyaraj, Vemika Chandra, Pawan Gupta, Charu Sharma, Sahil Mahajan
Publikováno v:
The Journal of Immunology. 197:244-255
Mycobacterium tuberculosis can evade host defense processes, thereby ensuring its survival and pathogenesis. In this study, we investigated the role of nuclear receptor, pregnane X receptor (PXR), in M. tuberculosis infection in human monocyte–deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c6443aaa908b5aabc64972de333b39
https://doi.org/10.4049/jimmunol.1600203
https://doi.org/10.4049/jimmunol.1600203
Autor:
Raman Parkesh, Ella Bhagyaraj, Pushpa Agrawal, Pawan Gupta, Saurabh Loharch, Hedwin Kitdorlang Dkhar, Anupriya Gopalsamy, Amandeep Kaur, Vemika Chandra, Kanmani Saminathan, Isha Bhutani, Kunchithapadam Swaminathan
Publikováno v:
Journal of Biological Chemistry. 290:76-89
GlgB (α-1,4-glucan branching enzyme) is the key enzyme involved in the biosynthesis of α-glucan, which plays a significant role in the virulence and pathogenesis of Mycobacterium tuberculosis. Because α-glucans are implicated in the survival of bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa81d36790ef52b85f1a201fa7cac71
https://doi.org/10.1074/jbc.m114.589200
https://doi.org/10.1074/jbc.m114.589200
Autor:
Ankita Saini, Hedwin Kitdorlang Dkhar, Pawan Gupta, Krishan Gopal Thakur, Shanmugam Mayilraj, Raman Parkesh, Sahil Mahajan, Ashish Arora, Arun Kumar Somavarapu, Sandeep Dave, Ravikanth Nanduri
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 193(1)
The cell wall of Mycobacterium tuberculosis is configured of bioactive lipid classes that are essential for virulence and potentially involved in the formation of foamy macrophages (FMs) and granulomas. Our recent work established crosstalk between M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c4cf46f8ba4e8aa5644293731956cf
https://pubmed.ncbi.nlm.nih.gov/24907344
https://pubmed.ncbi.nlm.nih.gov/24907344
Autor:
Ella Bhagyaraj, Sandeep Dave, Alka Rao, Ravikanth Nanduri, Pawan Gupta, Hedwin Kitdorlang Dkhar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e100862 (2014)
PLoS ONE, Vol 9, Iss 6, p e100862 (2014)
Uncontrolled adipogenesis and adipocyte proliferation have been connected to human comorbidities. Retinoic acid (RA) is known to inhibit adipocyte differentiation, however the underlying mechanisms have not been adequately understood. This study repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cb3eb04903d6d01a6935ef5520411c
http://europepmc.org/articles/PMC4069188
http://europepmc.org/articles/PMC4069188