Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hedwig S Kruitwagen"'
Autor:
Lindsay Van den Bossche, Vivien A C Schoonenberg, Iwan A Burgener, Louis C Penning, Ingrid M Schrall, Hedwig S Kruitwagen, Monique E van Wolferen, Guy C M Grinwis, Anne Kummeling, Jan Rothuizen, Jeroen F van Velzen, Nikolas Stathonikos, Martijn R Molenaar, Bernd J Helms, Jos F H M Brouwers, Bart Spee, Frank G van Steenbeek
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186491 (2017)
Non-alcoholic fatty liver disease (NAFLD) is a poorly understood multifactorial pandemic disorder. One of the hallmarks of NAFLD, hepatic steatosis, is a common feature in canine congenital portosystemic shunts. The aim of this study was to gain deta
Externí odkaz:
https://doaj.org/article/d24b3c0da950484b9acfde4701c548bc
Autor:
Talitha C. F. Spanjersberg, Loes A. Oosterhoff, Hedwig S. Kruitwagen, Noortje A. M. van den Dungen, Johannes C. M. Vernooij, Folkert W. Asselbergs, Michal Mokry, Bart Spee, Magdalena Harakalova, Frank G. van Steenbeek
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Vascular pathologies show locational predisposition throughout the body; further insights into the transcriptomics basis of this vascular heterogeneity are needed. We analyzed transcriptomes from cultured endothelial cells and vascular smoot
Externí odkaz:
https://doaj.org/article/084d9af137ee4c1b8e300e79be3a0038
Autor:
Hedwig S. Kruitwagen, Loes A. Oosterhoff, Ingrid G.W.H. Vernooij, Ingrid M. Schrall, Monique E. van Wolferen, Farah Bannink, Camille Roesch, Lisa van Uden, Martijn R. Molenaar, J. Bernd Helms, Guy C.M. Grinwis, Monique M.A. Verstegen, Luc J.W. van der Laan, Meritxell Huch, Niels Geijsen, Robert G. Vries, Hans Clevers, Jan Rothuizen, Baukje A. Schotanus, Louis C. Penning, Bart Spee
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 822-830 (2017)
Summary: Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of tractable cellular and animal models. Steatosis also occurs in cats, where it can cause severe hepatic failure. Previous studies demonstrate the p
Externí odkaz:
https://doaj.org/article/1b75311bbf3843328b88a26d9590e37a
Autor:
Xiaoyan Wu, Hsiaotzu Chien, Monique E. van Wolferen, Hedwig S. Kruitwagen, Loes A. Oosterhoff, Louis C. Penning
Publikováno v:
Veterinary Sciences, Vol 6, Iss 4, p 78 (2019)
Wilson’s disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (ATP7B). The disease is characterized by chronic hepatitis, eventually res
Externí odkaz:
https://doaj.org/article/c4b1737912334d57b76f0aa81e01a5be
Autor:
Michal Mokry, Hedwig S. Kruitwagen, Frank G. van Steenbeek, Magdalena Harakalova, Noortje A.M. van den Dungen, Loes A Oosterhoff, Talitha C.F. Spanjersberg, Bart Spee
The locational predisposition of vascular pathologies illustrates the need for a better insight into vascular heterogeneity. To investigate the transcriptomic basis of angiodiversity, we isolated and analyzed transcriptomes from endothelial cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a45852a7c305cc4a5804306c4fa10b
https://doi.org/10.1101/2021.10.20.465092
https://doi.org/10.1101/2021.10.20.465092
Autor:
Andre M. C. Meneses, Kerstin Schneeberger, Hedwig S. Kruitwagen, Louis C. Penning, Frank G. van Steenbeek, Iwan A. Burgener, Bart Spee
Publikováno v:
Veterinary Sciences, Vol 3, Iss 4, p 31 (2016)
Recent technical advances in the stem cell field have enabled the in vitro generation of complex structures resembling whole organs termed organoids. Most of these approaches employ culture systems that allow stem cell-derived or tissue progenitor ce
Externí odkaz:
https://doaj.org/article/dd1c353e60e349819ff2f4e75030038c
Autor:
Hedwig S, Kruitwagen, Loes A, Oosterhoff, Monique E, van Wolferen, Chen, Chen, Sathidpak, Nantasanti Assawarachan, Kerstin, Schneeberger, Anne, Kummeling, Giora, van Straten, Ies C, Akkerdaas, Christel R, Vinke, Frank G, van Steenbeek, Leonie W L, van Bruggen, Jeannette, Wolfswinkel, Guy C M, Grinwis, Sabine A, Fuchs, Helmuth, Gehart, Niels, Geijsen, Robert G, Vries, Hans, Clevers, Jan, Rothuizen, Baukje A, Schotanus, Louis C, Penning, Bart, Spee
Publikováno v:
Cells
The shortage of liver organ donors is increasing and the need for viable alternatives is urgent. Liver cell (hepatocyte) transplantation may be a less invasive treatment compared with liver transplantation. Unfortunately, hepatocytes cannot be expand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6956646f14c62888d55af9dd83411cf
https://pubmed.ncbi.nlm.nih.gov/32053895
https://pubmed.ncbi.nlm.nih.gov/32053895
Publikováno v:
Bioengineering
Bioengineering, Vol 6, Iss 4, p 88 (2019)
Bioengineering, Vol 6, Iss 4, p 88 (2019)
Wilson Disease is a rare autosomal recessive liver disorder in humans. Although its clinical presentation and age of onset are highly variable, hallmarks include signs of liver disease, neurological features and so-called Kayser-Fleischer rings in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7067153da0a1ec5cc33a6c743ff97143
http://europepmc.org/articles/PMC6955979
http://europepmc.org/articles/PMC6955979
Autor:
Hedwig S. Kruitwagen, Louis C. Penning
Publikováno v:
Annals of translational medicine. 7(Suppl 2)
Copper toxicosis is frequently encountered in various dog breeds. A number of differences and similarities occur between Wilson disease and copper toxicosis in Bedlington terriers, caused by a mutation in the COMMD1 gene, and copper toxicosis in Labr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c8f176dc03fe1d6758f1e00afcec89
https://pubmed.ncbi.nlm.nih.gov/31179308
https://pubmed.ncbi.nlm.nih.gov/31179308
Autor:
Hedwig S. Kruitwagen, Bart Spee, Hille Fieten, Frank G. van Steenbeek, Baukje A. Schotanus, Louis C. Penning
Publikováno v:
European Medical Journal Hepatology, Vol 2, Iss 1, Pp 48-54 (2014)
Alternatives for liver transplantation in severe liver disease are urgently needed in view of the limited availability of donor livers. The use of embryonic stem cells (ES) or hepatic progenitor cells (HPC) has been investigated in mice models of acu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e95f83724ff148b63acdf41c81f5a52
http://emjreviews.com/wp-content/uploads/TRANSLATION-FROM-MICE-TO-MEN-ARE-DOGS-A-DODGY-INTERMEDIATE.pdf
http://emjreviews.com/wp-content/uploads/TRANSLATION-FROM-MICE-TO-MEN-ARE-DOGS-A-DODGY-INTERMEDIATE.pdf