Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Hedrich Hans"'
Autor:
Scheumann Marina, Roser Anna-Elisa, Konerding Wiebke, Bleich Eva, Hedrich Hans-Jürgen, Zimmermann Elke
Publikováno v:
Frontiers in Zoology, Vol 9, Iss 1, p 36 (2012)
Abstract Introduction Human speech does not only communicate linguistic information but also paralinguistic features, e.g. information about the identity and the arousal state of the sender. Comparable morphological and physiological constraints on v
Externí odkaz:
https://doaj.org/article/304e7f1ac8d0439a928038722e203699
Autor:
Zschemisch Nils-Holger, Glage Silke, Wedekind Dirk, Weinstein Edward J, Cui Xiaoxia, Dorsch Martina, Hedrich Hans-Jürgen
Publikováno v:
BMC Immunology, Vol 13, Iss 1, p 60 (2012)
Abstract Background Engineered zinc-finger nucleases (ZFN) represented an innovative method for the genome manipulation in vertebrates. ZFN introduced targeted DNA double strand breaks (DSB) and initiated non-homologous end joining (NHEJ) after pronu
Externí odkaz:
https://doaj.org/article/f0a07a48faba4c599a378aa416a3e2da
Autor:
Sterenczak Katharina A, Meier Martin, Glage Silke, Meyer Matthias, Willenbrock Saskia, Wefstaedt Patrick, Dorsch Martina, Bullerdiek Jörn, Escobar Hugo, Hedrich Hans, Nolte Ingo
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 284 (2012)
Abstract Background Cell lines represent a key tool in cancer research allowing the generation of neoplasias which resemble initial tumours in in-vivo animal models. The characterisation of early tumour development is of major interest in order to ev
Externí odkaz:
https://doaj.org/article/3631c206b83e436aa10692308e00dc4a
Autor:
Glage Silke, Klinge Petra M, Miller Miles C, Wallrapp Christine, Geigle Peter, Hedrich Hans J, Brinker Thomas
Publikováno v:
Fluids and Barriers of the CNS, Vol 8, Iss 1, p 18 (2011)
Abstract Background Neuropeptides may have considerable potential in the treatment of acute and chronic neurological diseases. Encapsulated genetically engineered cells have been suggested as a means for sustained local delivery of such peptides to t
Externí odkaz:
https://doaj.org/article/52d4b132313e4969b3915ba8a8b281e7
Autor:
Winkler Susanne, Willenbrock Saskia, Sterenczak Katharina A, Soller Jan T, Escobar Hugo, Fork Melani AM, Dorsch Martina, Reimann-Berg Nicola, Hedrich Hans J, Bullerdiek Jörn, Nolte Ingo
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 240 (2008)
Abstract Background Prostate cancer is a frequent finding in man. In dogs, malignant disease of the prostate is also of clinical relevance, although it is a less common diagnosis. Even though there are numerous differences in origin and development o
Externí odkaz:
https://doaj.org/article/78b0157bdc544c51b79f29717d871baa
Autor:
Leonhard-Marek Sabine, Burmester Marion, Bot Alice, Charizopoulou Nikoletta, Wedekind Dirk, Jansen Silke, Dorsch Martina, Stanke Frauke, Wilke Martina, Tóth Balázs, de Jonge Hugo R, Hedrich Hans-Jürgen, Breves Gerhard, Tümmler Burkhard
Publikováno v:
BMC Genetics, Vol 9, Iss 1, p 28 (2008)
Abstract Background A major boost to cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains genera
Externí odkaz:
https://doaj.org/article/e21588a5c0394e37afba411aa1084183
Autor:
Stanke Frauke, Jansen Silke, Jorna Huub, Bot Alice, Dorsch Martina, Wilke Martina, Charizopoulou Nikoletta, Hedrich Hans J, de Jonge Hugo R, Tümmler Burkhard
Publikováno v:
BMC Genetics, Vol 7, Iss 1, p 18 (2006)
Abstract Background From the original CftrTgH(neoim)Hgu mutant mouse model with a divergent genetic background (129P2, C57BL/6, MF1) we have generated two inbred CftrTgH(neoim)Hgu mutant strains named CF/1-CftrTgH(neoim)Hgu and CF/3-CftrTgH(neoim)Hgu
Externí odkaz:
https://doaj.org/article/af37548e85c5459ebe69d18866156bfb
Publikováno v:
BMC Genomics, Vol 6, Iss 1, p 170 (2005)
Abstract Background The laboratory rat (Rattus norvegicus) is an important model for studying many aspects of human health and disease. Detailed knowledge on genetic variation between strains is important from a biomedical, particularly pharmacogenet
Externí odkaz:
https://doaj.org/article/ac890a41d924467996c663e89742a00c
Autor:
Dorin Julia R, Stanke Frauke, Dorsch Martina, Jansen Silke, Charizopoulou Nikoletta, Hedrich Hans-Jürgen, Tümmler Burkhard
Publikováno v:
BMC Genetics, Vol 5, Iss 1, p 6 (2004)
Abstract Background A major boost to the cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains ge
Externí odkaz:
https://doaj.org/article/e912b2f19c4b4e7b8e78559295bcc970
Autor:
Lewis, Kevin M., Schiviz, Alexandra, Hedrich, Hans-Christian, Regenbogen, Johannes, Goppelt, Andreas
Publikováno v:
In International Journal of Surgery September 2014 12(9):940-944