Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Hedley C. Freake"'
Autor:
Hedley C. Freake, Bruce J. Grattan
Publikováno v:
Nutrients, Vol 4, Iss 7, Pp 648-675 (2012)
Nutrients
Nutrients
Zinc is a trace mineral which is vital for the functioning of numerous cellular processes, is critical for growth, and may play an important role in cancer etiology and outcome. The intracellular levels of this mineral are regulated through the coord
Autor:
Anthony Palermo, Amrita Dutta, Leelyn Chong, Robert G. Michel, Hedley C. Freake, Kavitha Sankavaram
Publikováno v:
Nutrition Research. 31:404-411
We have demonstrated that reducing zinc availability with the extracellular chelator diethylenetriaminepentaacetic acid (DTPA) causes rapid inhibition of cellular zinc efflux in H4IIE hepatoma cells but increases zinc efflux in primary hepatocytes. S
Autor:
Nicholas Altieri, Karen L. Konopelski, Hedley C. Freake, John W. Carbone, Lisa M. Vislocky, Jeffrey M. Anderson, Robert R. Wolfe, Stefan M. Pasiakos, Arny A. Ferrando, Nancy R. Rodriguez
Publikováno v:
The Journal of Nutrition. 140:745-751
To date, few studies have characterized the influence of energy deprivation on direct measures of skeletal muscle protein turnover. In this investigation, we characterized the effect of an acute, moderate energy deficit (10 d) on mixed muscle fractio
Autor:
Hedley C. Freake
Publikováno v:
Nutrition Reviews. 56:185-189
Uncoupling protein, originally described in the inner mitochondrial membrane of brown adipose tissue, permits the oxidation of fuels without the generation of adenosine triphosphate (ATP). Closely related proteins have now been found in many other ti
Publikováno v:
British Journal of Nutrition. 99:1182-1185
Green tea catechins are known to have hypocholesterolaemic effects in animals and human subjects. In the present study, we investigated the effects of green tea catechins on the mRNA level and promoter activity of hepatic cholesterol 7α-hydroxylase
Publikováno v:
The Journal of Nutrition. 137:1165-1170
We previously demonstrated that a diet therapy involving consumption of 7.28 g psyllium (PSY) and 2 g of plant sterols (PS) per day reduced LDL cholesterol from 3.6 +/- 0.7 to 3.1 +/- 0.8 mmol/L (P < 0.01) and decreased the number of intermediate den
Autor:
J. B. German, Grace S. Marquis, Hedley C. Freake, Douglas G. Burrin, D. E. Bauman, J. A. Milner, Kathleen M. Rasmussen, Steven H. Zeisel, Dennis M. Bier, Gretel H. Pelto, Samuel Klein
Publikováno v:
The Journal of Nutrition. 135:1613-1616
The concept of the nutritional phenotype is proposed as a defined and integrated set of genetic, proteomic, metabolomic, functional, and behavioral factors that, when measured, form the basis for assessment of human nutritional status. The nutritiona
Publikováno v:
The Journal of Nutrition. 135:735-739
To determine whether changes in plasma lipids following a weight loss program were related to modifications in gene expression of the LDL receptor (LDL-R), lipoprotein lipase (LPL), and 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, overweight/o
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:2251-2254
The synthesis of a coumarin-cyclen conjugate-based zinc-specific chemosensor and its ability to sense Zn(2+) in vitro is described. Using fluorescence microscopy, the chemosensor was shown to be capable of imaging Zn(2+) in live rat pituitary tumour
Publikováno v:
The Journal of Nutrition. 133:67-70
Psyllium (PSY) intake decreases plasma LDL cholesterol (LDL-C) in men and pre- and post-menopausal women while PSY effects on plasma triglycerides (TG) are sex related. A significant decrease in plasma TG was observed in men while postmenopausal wome