The exon-skipping oligonucleotide, KitStop, depletes tissue-resident mast cells in vivo to ameliorate anaphylaxis.

Autor: Hedgespeth BA; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, United States.; Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, United States.; Comparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.; Comparative Medicine and Translational Research Training Program, North Carolina State University, Raleigh, NC, United States., Snider DB; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, United States.; Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, United States.; Comparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.; Comparative Medicine and Translational Research Training Program, North Carolina State University, Raleigh, NC, United States., Bitting KJ; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, United States., Cruse G; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, United States.; Comparative Medicine Institute, North Carolina State University, Raleigh, NC, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Jan 31; Vol. 14, pp. 1006741. Date of Electronic Publication: 2023 Jan 31 (Print Publication: 2023).

Identification of an ATP/P2X7/mast cell pathway mediating ozone-induced bronchial hyperresponsiveness.

Autor: Kong X; Department of Respiratory and Critical Care Medicine, The First Hospital of Shanxi Medical University, Taiyuan, China., Bennett WC; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., Jania CM; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., Chason KD; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., German Z; Marsico Lung Institute and.; Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Adouli J; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., Budney SD; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., Oby BT; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., van Heusden C; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., Lazarowski ER; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., Jaspers I; Department of Pediatrics and Center for Environmental Medicine, Asthma, and Lung Biology and., Randell SH; Marsico Lung Institute and.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA., Hedgespeth BA; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Cruse G; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA., Hua X; Department of Head and Neck Surgery & Communication Sciences, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Otolaryngology - Head and Neck Surgery, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Schworer SA; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA.; Division of Allergy and Immunology, Department of Pediatrics, and., Smith GJ; Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kelada SN; Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Tilley SL; Marsico Lung Institute and.; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, North Carolina, USA.

Publikováno v: JCI insight [JCI Insight] 2021 Nov 08; Vol. 6 (21). Date of Electronic Publication: 2021 Nov 08.

Dysbiosis of fecal microbiota in cats with naturally occurring and experimentally induced Tritrichomonas foetus infection.

Autor: Bierlein M; Department of Clinical Sciences, College of Veterinary Medicine and Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America., Hedgespeth BA; Department of Clinical Sciences, College of Veterinary Medicine and Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America., Azcarate-Peril MA; Division of Gastroenterology and Hepatology, Department of Medicine, UNC Microbiome Core, Center for Gastrointestinal Biology and Disease, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America., Stauffer SH; Department of Clinical Sciences, College of Veterinary Medicine and Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America., Gookin JL; Department of Clinical Sciences, College of Veterinary Medicine and Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina, United States of America.

Publikováno v: PloS one [PLoS One] 2021 Feb 19; Vol. 16 (2), pp. e0246957. Date of Electronic Publication: 2021 Feb 19 (Print Publication: 2021).

Association of fecal sample collection technique and treatment history with Tritrichomonas foetus polymerase chain reaction test results in 1717 cats.

Autor: Hedgespeth BA; Department of Clinical Sciences, North Carolina State University, Raleigh, North Carolina., Stauffer SH; Department of Clinical Sciences, North Carolina State University, Raleigh, North Carolina., Robertson JB; College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina., Gookin JL; Department of Clinical Sciences, North Carolina State University, Raleigh, North Carolina.

Publikováno v: Journal of veterinary internal medicine [J Vet Intern Med] 2020 Mar; Vol. 34 (2), pp. 734-741. Date of Electronic Publication: 2020 Feb 10.

What Is Your Diagnosis? Gastrointestinal pneumatosis.

Autor: Hedgespeth BA, Pérez ML

Publikováno v: Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2017 Jul 01; Vol. 251 (1), pp. 37-39.