Genomic landscape of Down syndrome-associated acute lymphoblastic leukemia.

Autor: Li Z; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN., Chang TC; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN., Junco JJ; Department of Pediatrics, Baylor College of Medicine, Houston, TX., Devidas M; Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN., Li Y; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN., Yang W; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN., Huang X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN., Hedges DJ; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN., Cheng Z; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN., Shago M; Department of Pathobiology and Laboratory Medicine, University of Toronto, Toronto, ON, Canada., Carroll AJ; Department of Genetics, The University of Alabama at Birmingham, Birmingham, AL., Heerema NA; Department of Pathology, The Ohio State University, Columbus, OH., Gastier-Foster J; Department of Pediatrics, Baylor College of Medicine, Houston, TX.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX., Wood BL; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA., Borowitz MJ; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD., Sanclemente L; Department of Pediatrics, Baylor College of Medicine, Houston, TX., Raetz EA; Department of Pediatrics and Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY., Hunger SP; Department of Pediatrics and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA.; The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Feingold E; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA., Rosser TC; Department of Human Genetics, Emory University, Atlanta, GA., Sherman SL; Department of Human Genetics, Emory University, Atlanta, GA., Loh ML; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA., Mullighan CG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN., Yu J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN., Wu G; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN., Lupo PJ; Department of Pediatrics, Baylor College of Medicine, Houston, TX., Rabin KR; Department of Pediatrics, Baylor College of Medicine, Houston, TX., Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.; Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, TN.

Publikováno v: Blood [Blood] 2023 Jul 13; Vol. 142 (2), pp. 172-184.

The genomic landscape of pediatric acute lymphoblastic leukemia.

Autor: Brady SW; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Roberts KG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Gu Z; Department of Computational and Quantitative Medicine & Systems Biology, Beckman Research Institute of City of Hope, Duarte, CA, USA., Shi L; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Pounds S; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Pei D; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Cheng C; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Dai Y; Department of Biostatistics, University of Florida, Gainesville, FL, USA., Devidas M; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA., Qu C; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Hill AN; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Payne-Turner D; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Ma X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Iacobucci I; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Baviskar P; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wei L; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Arunachalam S; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Hagiwara K; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Liu Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Flasch DA; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Liu Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Parker M; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Chen X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Elsayed AH; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA., Pathak O; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Li Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Fan Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Michael JR; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Rusch M; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wilkinson MR; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Foy S; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Hedges DJ; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Newman S; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Zhou X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Reilly C; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Sioson E; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Rice SV; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Pastor Loyola V; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wu G; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA., Rampersaud E; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA., Reshmi SC; Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA., Gastier-Foster J; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Guidry Auvil JM; Office of Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Office of Data Sharing, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Gesuwan P; Office of Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Smith MA; Cancer Therapeutics Evaluation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Winick N; Department of Pediatric Hematology Oncology and Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA., Carroll AJ; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA., Heerema NA; The Ohio State University, Columbus, OH, USA., Harvey RC; Department of Pathology, University of New Mexico Cancer Center, Albuquerque, NM, USA., Willman CL; Mayo Clinical Comprehensive Cancer Center, Rochester, MN, USA., Larsen E; Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME, USA., Raetz EA; Department of Pediatrics and Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA., Borowitz MJ; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA., Wood BL; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA., Carroll WL; Department of Pediatrics and Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA., Zweidler-McKay PA; ImmunoGen, Inc., Waltham, MA, USA., Rabin KR; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Mattano LA; HARP Pharma Consulting, Mystic, CT, USA., Maloney KW; Department of Pediatrics and Children's Hospital Colorado, University of Colorado, Aurora, CO, USA., Winter SS; Children's Minnesota Research Institute and Cancer and Blood Disorders Program, Minneapolis, MN, USA., Burke MJ; Division of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI, USA., Salzer W; Uniformed Services University, School of Medicine, Bethesda, MD, USA., Dunsmore KP; Department of Pediatrics, University of Virginia, Charlottesville, VA, USA., Angiolillo AL; Children's National Medical Center, Washington, DC, USA., Crews KR; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Downing JR; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Jeha S; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Pui CH; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Evans WE; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Relling MV; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Gerhard DS; Office of Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Loh ML; Department of Pediatrics, Benioff Children's Hospital and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Hunger SP; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Hungers@chop.edu., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. jinghui.zhang@stjude.org., Mullighan CG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA. charles.mullighan@stjude.org.

Publikováno v: Nature genetics [Nat Genet] 2022 Sep; Vol. 54 (9), pp. 1376-1389. Date of Electronic Publication: 2022 Sep 01.

Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing.

Autor: Newman S; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Nakitandwe J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Kesserwan CA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Azzato EM; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Wheeler DA; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Rusch M; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Shurtleff S; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Hedges DJ; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Hamilton KV; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Foy SG; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Edmonson MN; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Thrasher A; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Bahrami A; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Orr BA; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Klco JM; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Gu J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Harrison LW; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Wang L; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Clay MR; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Ouma A; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Silkov A; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Liu Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Zhang Z; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Liu Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Brady SW; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Zhou X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Chang TC; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Pande M; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Davis E; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Becksfort J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Patel A; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Wilkinson MR; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Rahbarinia D; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Kubal M; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Maciaszek JL; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Pastor V; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Knight J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Gout AM; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Wang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Gu Z; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Mullighan CG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., McGee RB; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Quinn EA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Nuccio R; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Mostafavi R; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Gerhardt EL; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Taylor LM; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Valdez JM; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Hines-Dowell SJ; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Pappo AS; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Robinson G; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Johnson LM; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Pui CH; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Ellison DW; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Downing JR; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Nichols KE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.

Publikováno v: Cancer discovery [Cancer Discov] 2021 Dec 01; Vol. 11 (12), pp. 3008-3027.

Integrating Circle-Seq with transcriptomics reveals genome-wide characterization of extrachromosomal circular DNA for dilated cardiomyopathy.

Autor: Lin, Zhenhao¹ (AUTHOR), Dai, Fangjie² (AUTHOR), Li, Bo^3,4 (AUTHOR), Zhao, Yongchao^5,6 (AUTHOR) zhaoyc3988@126.com, Wang, Changqian¹ (AUTHOR) wangcq1218@sh9hospital.org.cn

Publikováno v: Biology Direct. 11/29/2024, Vol. 19 Issue 1, p1-17. 17p.

Widespread HCD-tRNA derived SINEs in bivalves rely on multiple LINE partners and accumulate in genic regions.

Autor: Martelossi, Jacopo¹ (AUTHOR) jacopo.martelossi2@unibo.it, Iannello, Mariangela¹ (AUTHOR), Ghiselli, Fabrizio¹ (AUTHOR) fabrizio.ghiselli@unibo.it, Luchetti, Andrea¹ (AUTHOR)

Publikováno v: Mobile DNA. 10/16/2024, Vol. 15 Issue 1, p1-16. 16p.