The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.

Autor: Dombernowsky SL; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Samsøe-Petersen J; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Petersen CH; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Instrell R; High Throughput Screening Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK., Hedegaard AM; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Thomas L; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 507 Bridgeside Point II, 450 Technology Drive, Pittsburgh, Pennsylvania 15219, USA., Atkins KM; Department of Cell and Developmental Biology, Oregon Health &Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA., Auclair S; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 507 Bridgeside Point II, 450 Technology Drive, Pittsburgh, Pennsylvania 15219, USA., Albrechtsen R; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Mygind KJ; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Fröhlich C; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Howell M; High Throughput Screening Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK., Parker P; 1] Protein Phosphorylation Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK [2] Division of Cancer Studies, King's College London, New Hunts House, Guy's Campus, London SE1 1UL, UK., Thomas G; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 507 Bridgeside Point II, 450 Technology Drive, Pittsburgh, Pennsylvania 15219, USA., Kveiborg M; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark.

Publikováno v: Nature communications [Nat Commun] 2015 Jun 25; Vol. 6, pp. 7518. Date of Electronic Publication: 2015 Jun 25.