The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.

Autor: Dombernowsky SL; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Samsøe-Petersen J; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Petersen CH; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Instrell R; High Throughput Screening Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK., Hedegaard AM; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Thomas L; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 507 Bridgeside Point II, 450 Technology Drive, Pittsburgh, Pennsylvania 15219, USA., Atkins KM; Department of Cell and Developmental Biology, Oregon Health &Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA., Auclair S; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 507 Bridgeside Point II, 450 Technology Drive, Pittsburgh, Pennsylvania 15219, USA., Albrechtsen R; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Mygind KJ; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Fröhlich C; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark., Howell M; High Throughput Screening Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK., Parker P; 1] Protein Phosphorylation Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK [2] Division of Cancer Studies, King's College London, New Hunts House, Guy's Campus, London SE1 1UL, UK., Thomas G; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 507 Bridgeside Point II, 450 Technology Drive, Pittsburgh, Pennsylvania 15219, USA., Kveiborg M; Department of Biomedical Sciences &Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, 2200 Copenhagen N, Denmark.

Publikováno v: Nature communications [Nat Commun] 2015 Jun 25; Vol. 6, pp. 7518. Date of Electronic Publication: 2015 Jun 25.

ADAM17 is an essential attachment factor for classical swine fever virus.

Autor: Yuan, Fei¹ (AUTHOR), Li, Dandan² (AUTHOR), Li, Changyao³ (AUTHOR), Zhang, Yanan² (AUTHOR), Song, Hao⁴ (AUTHOR), Li, Suhua² (AUTHOR), Deng, Hongkui⁵ (AUTHOR) hongkui_deng@pku.edu.cn, Gao, George F.¹ (AUTHOR) hongkui_deng@pku.edu.cn, Zheng, Aihua^2,6,7 (AUTHOR) hongkui_deng@pku.edu.cn

Publikováno v: PLoS Pathogens. 3/8/2021, Vol. 17 Issue 3, p1-18. 18p.

Contribution of ADAM17 and related ADAMs in cardiovascular diseases.

Autor: Kawai, Tatsuo, Elliott, Katherine J., Scalia, Rosario, Eguchi, Satoru

Publikováno v: Cellular & Molecular Life Sciences; May2021, Vol. 78 Issue 9, p4161-4187, 27p

GRP78 protects a disintegrin and metalloprotease 17 against protein-disulfide isomerase A6 catalyzed inactivation.

Autor: Schäfer, Miriam, Granato, Daniela C., Krossa, Sebastian, Bartels, Anne‐Kathrin, Yokoo, Sami, Düsterhöft, Stefan, Koudelka, Tomas, Scheidig, Axel J., Tholey, Andreas, Paes Leme, Adriana F., Grötzinger, Joachim, Lorenzen, Inken

Publikováno v: FEBS Letters; Nov2017, Vol. 591 Issue 21, p3567-3587, 21p

Organelle Contact Sites : From Molecular Mechanism to Disease

Autor: Mitsuo Tagaya, Thomas Simmen

This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the i