Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Heddy Kerestes"'
Autor:
Shujing Liu, Gao Zhang, Jianping Guo, Xiang Chen, Jingce Lei, Kan Ze, Liyun Dong, Xiangpeng Dai, Yang Gao, Daisheng Song, Brett L. Ecker, Ruifeng Yang, Caitlin Feltcher, Kai Peng, Cheng Feng, Hui Chen, Rebecca X. Lee, Heddy Kerestes, Jingwen Niu, Suresh Kumar, Weiting Xu, Jie Zhang, Zhi Wei, James S. Martin, Xiaoming Liu, Gordon Mills, Yiling Lu, Wei Guo, Lunquan Sun, Lin Zhang, Ashani Weeraratna, Meenhard Herlyn, Wenyi Wei, Frank S. Lee, Xiaowei Xu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Prolyl hydroxylase domain protein 2 (PHD2) regulates cellular response to hypoxia. Here the authors show that PHD2 is downregulated in melanoma and that PHD2 depletion, in a mouse model, promotes the progression of benign melanocytic lesions into mel
Externí odkaz:
https://doaj.org/article/473123c7d99e44289a92d2ad275cec64
Autor:
Shujing Liu, Gao Zhang, Jianping Guo, Xiang Chen, Jingce Lei, Kan Ze, Liyun Dong, Xiangpeng Dai, Yang Gao, Daisheng Song, Brett L. Ecker, Ruifeng Yang, Caitlin Feltcher, Kai Peng, Cheng Feng, Hui Chen, Rebecca X. Lee, Heddy Kerestes, Jingwen Niu, Suresh Kumar, Weiting Xu, Jie Zhang, Zhi Wei, James S. Martin, Xiaoming Liu, Gordon Mills, Yiling Lu, Wei Guo, Lunquan Sun, Lin Zhang, Ashani Weeraratna, Meenhard Herlyn, Wenyi Wei, Frank S. Lee, Xiaowei Xu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the spelling of the author Brett L. Ecker, which was incorrectly given as Brett Ecker. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/7148f057553a4fa8a5fb53daf14a09ad
Autor:
Wenyi Wei, Yang Gao, Lin Zhang, Ruifeng Yang, Shujing Liu, Gao Zhang, Jie Zhang, Yiling Lu, Liyun Dong, Jianping Guo, Jingce Lei, Hui Chen, James S. Martin, Xiangpeng Dai, Kai Peng, Suresh M. Kumar, Caitlin Feltcher, Jingwen Niu, Wei Guo, Kan Ze, Gordon B. Mills, Brett L. Ecker, Meenhard Herlyn, Xiaowei Xu, Frank S. Lee, Zhi Wei, Lunquan Sun, Ashani T. Weeraratna, Heddy Kerestes, Xiaoming Liu, Cheng Feng, Xiang Chen, Daisheng Song, Rebecca Lee, Weiting Xu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Prolyl hydroxylase domain protein 2 (PHD2) is a well-known master oxygen sensor. However, the role of PHD2 in tumor initiation remains controversial. We find that during the transition of human nevi to melanoma, the expression of PHD2 protein is sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a2995898ee71068d6540cfbf6edeef
http://link.springer.com/article/10.1038/s41467-018-07126-9
http://link.springer.com/article/10.1038/s41467-018-07126-9
Autor:
Liyun Dong, Brett L. Ecker, Gao Zhang, Jingce Lei, Gordon B. Mills, Cheng Feng, Caitlin Feltcher, Daisheng Song, Suresh M. Kumar, Rebecca Lee, Jianping Guo, James S. Martin, Xiangpeng Dai, Zhi Wei, Lunquan Sun, Jie Zhang, Yiling Lu, Kai Peng, Ashani T. Weeraratna, Jingwen Niu, Xiaoming Liu, Heddy Kerestes, Kan Ze, Frank S. Lee, Xiang Chen, Yang Gao, Wenyi Wei, Wei Guo, Meenhard Herlyn, Lin Zhang, Ruifeng Yang, Hui Chen, Weiting Xu, Shujing Liu, Xiaowei Xu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the spelling of the author Brett L. Ecker, which was incorrectly given as Brett Ecker. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b02d6fbad06f1bf7f1d0d26d468bce1
https://doaj.org/article/7148f057553a4fa8a5fb53daf14a09ad
https://doaj.org/article/7148f057553a4fa8a5fb53daf14a09ad
Autor:
Rebecca Lee, Patrick R. Arsenault, Brian Keith, Terence R.J. Lappin, Frank S. Lee, Fei Pei, Heddy Kerestes, M. Celeste Simon, Melanie J. Percy, Tejvir S. Khurana
Publikováno v:
Journal of Biological Chemistry. 288:33571-33584
The central pathway for controlling red cell mass is the PHD (prolyl hydroxylase domain protein):hypoxia-inducible factor (HIF) pathway. HIF, which is negatively regulated by PHD, activates numerous genes, including ones involved in erythropoiesis, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02d7220c9e09978ce840de69dd06def
https://doi.org/10.1074/jbc.m113.482364
https://doi.org/10.1074/jbc.m113.482364
Autor:
Qiulin Tan, Heddy Kerestes, Frank S. Lee, Terence R.J. Lappin, Ralph A. Pietrofesa, Tejvir S. Khurana, Li Chen, Melpo Christofidou-Solomidou, Melanie J. Percy
Publikováno v:
Journal of Biological Chemistry. 288:17134-17144
The central pathway for oxygen-dependent control of red cell mass is the prolyl hydroxylase domain protein (PHD):hypoxia inducible factor (HIF) pathway. PHD site specifically prolyl hydroxylates the transcription factor HIF-α, thereby targeting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf233bb1f48b5c24b7f2a0717b82bc40
https://doi.org/10.1074/jbc.m112.444059
https://doi.org/10.1074/jbc.m112.444059