A Comparison Between Recombinant Listeria GAPDH Proteins and GAPDH Encoding mRNA Conjugated to Lipids as Cross-Reactive Vaccines for Listeria, Mycobacterium, and Streptococcus

Autor: Hector Teran-Navarro, David Salcines-Cuevas, Ricardo Calderon-Gonzalez, Raquel Tobes, Jorge Calvo-Montes, Inmaculada Concepción Pérez-Del Molino Bernal, Sonsoles Yañez-Diaz, Manuel Fresno, Carmen Alvarez-Dominguez

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Cross-reactive vaccines recognize common molecular patterns in pathogens and are able to confer broad spectrum protection against different infections. Antigens common to pathogenic bacteria that induce broad immune responses, such as the glyceraldeh

Externí odkaz: https://doaj.org/article/a41c4dc468da4c2d89cb65d45e5a75db

Glyceraldehyde-3-phosphate Dehydrogenase Common Peptides of Listeria monocytogenes, Mycobacterium marinum and Streptococcus pneumoniae as Universal Vaccines

Autor: Sonsoles Yañez-Diaz, Jorge Calvo-Montes, David Salcines-Cuevas, Carmen Alvarez-Dominguez, Paula Torres-Rodriguez, Ricardo Calderon-Gonzalez, Manuel Fresno, I. Concepción Pérez Del Molino-Bernal, Hector Teran-Navarro, Raquel Tobes

Publikováno v: Vaccines
Volume 9
Issue 3
Vaccines, Vol 9, Iss 269, p 269 (2021)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Digital.CSIC. Repositorio Institucional del CSIC

Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera Listeria, Mycobacterium and Stre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8973b7f99fd03bbf7f8aa5bcb37f7af8

GNP-GAPDH1-22 nanovaccines prevent neonatal listeriosis by blocking microglial apoptosis and bacterial dissemination

Autor: Sonsoles Yañez-Diaz, Fernando Rivera, Hector Teran-Navarro, Javier Gómez-Román, Isabel García, Claudia González-Rico, Carmen Alvarez-Dominguez, Manuel Fresno, Soledad Penadés, Javier Freire, Marco Marradi, David Salcines-Cuevas, Carmen Punzón, Elisabet Frande-Cabanes, Ana Castañeda-Sampedro, Ricardo Calderon-Gonzalez, M. Carmen Fariñas, José María Marimón, Mirian Alkorta-Gurrutxaga, Aida San Nicolas-Gomez

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Oncotarget. 2017 Jul 20;8(33):53916-53934
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

Clinical cases of neonatal listeriosis are associated with brain disease and fetal loss due to complications in early or late pregnancy, which suggests that microglial function is altered. This is believed to be the first study to link microglial apo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd59113e83e6461d6eb08fd124e6212
https://doi.org/10.18632/oncotarget.19405

Dendritic cell therapy in melanoma

Autor: Javier Freire, Ricardo Calderon-Gonzalez, Hector Teran-Navarro, Almudena García-Castaño, Jose Javier Gomez-Roman, Fernando Rivera, Carmen Alvarez-Dominguez, David Salcines-Cuevas

Publikováno v: Annals of translational medicine. 5(19)

Dendritic cell (DC) vaccines are cancer vaccines used currently as melanoma therapies. They act as adjuvants initiating the immune responses, but not only as they can also have effector activities redirecting cytotoxic CD8+ T cells against melanoma.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cac2928aaef5a594fe9acfcc533941
https://pubmed.ncbi.nlm.nih.gov/29114544

Pregnancy Vaccination with Gold Glyco-Nanoparticles Carrying Listeria monocytogenes Peptides Protects against Listeriosis and Brain- and Cutaneous-Associated Morbidities

Autor: Javier Freire, Soledad Penadés, Isabel García, Hector Teran-Navarro, Eva Ferrandez-Fernandez, Sonsoles Yañez-Diaz, Elisabet Frande-Cabanes, Carmen Alvarez-Dominguez, Marco Marradi, Javier Gómez-Román, Ricardo Calderon-Gonzalez

Publikováno v: Nanomaterials, Vol 6, Iss 8, p 151 (2016)
Nanomaterials; Volume 6; Issue 8; Pages: 151
Nanomaterials

Listeriosis is a fatal infection for fetuses and newborns with two clinical main morbidities in the neonatal period, meningitis and diffused cutaneous lesions. In this study, we vaccinated pregnant females with two gold glyconanoparticles (GNP) loade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014a2d9bf5f9728bad374f4d80964438
http://www.mdpi.com/2079-4991/6/8/151