Zobrazeno 1 - 10
of 346
pro vyhledávání: '"Hector Martinez"'
Autor:
Leto Luana Riebel, Zhinuo Jenny Wang, Hector Martinez-Navarro, Cristian Trovato, Julia Camps, Lucas Arantes Berg, Xin Zhou, Ruben Doste, Rafael Sachetto Oliveira, Rodrigo Weber dos Santos, Jacopo Biasetti, Blanca Rodriguez
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Human-based modelling and simulation offer an ideal testbed for novel medical therapies to guide experimental and clinical studies. Myocardial infarction (MI) is a common cause of heart failure and mortality, for which novel therapies are ur
Externí odkaz:
https://doaj.org/article/07ce5339c7314d4ca4646c737d74cf59
Autor:
Juan Lorenzo Rodriguez-Flores, Shareef Khalid, Neelroop Parikshak, Asif Rasheed, Bin Ye, Manav Kapoor, Joshua Backman, Farshid Sepehrband, Silvio Alessandro Di Gioia, Sahar Gelfman, Tanima De, Nilanjana Banerjee, Deepika Sharma, Hector Martinez, Sofia Castaneda, David D’Ambrosio, Xingmin A. Zhang, Pengcheng Xun, Ellen Tsai, I-Chun Tsai, Regeneron Genetics Center, Maleeha Zaman Khan, Muhammad Jahanzaib, Muhammad Rehan Mian, Muhammad Bilal Liaqat, Khalid Mahmood, Tanvir Us Salam, Muhammad Hussain, Javed Iqbal, Faizan Aslam, Michael N. Cantor, Gannie Tzoneva, John Overton, Jonathan Marchini, Jeffrey G. Reid, Aris Baras, Niek Verweij, Luca A. Lotta, Giovanni Coppola, Katia Karalis, Aris Economides, Sergio Fazio, Wolfgang Liedtke, John Danesh, Ayeesha Kamal, Philippe Frossard, Thomas Coleman, Alan R. Shuldiner, Danish Saleheen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The genetic factors of stroke in South Asians are largely unexplored. Exome-wide sequencing and association analysis (ExWAS) in 75 K Pakistanis identified NM_000435.3(NOTCH3):c.3691 C > T, encoding the missense amino acid substitution p.Arg1
Externí odkaz:
https://doaj.org/article/6deb4ea097ec40d293f51e257ce35689
Autor:
David Just, Vladimír Palivec, Kateřina Bártová, Lucie Bednárová, Markéta Pazderková, Ivana Císařová, Hector Martinez-Seara, Ullrich Jahn
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Peptide-like foldamers controlled by normal amide backbone hydrogen bonding have been extensively studied, and their folding patterns largely rely on configurational and conformational constraints induced by the steric properties of backbone
Externí odkaz:
https://doaj.org/article/4bc6729162984a04ad2cea3a621676bd
Autor:
Federica Scollo, Carmelo Tempra, Hüseyin Evci, Miguel Riopedre-Fernandez, Agnieszka Olżyńska, Matti Javanainen, Arunima Uday, Marek Cebecauer, Lukasz Cwiklik, Hector Martinez-Seara, Pavel Jungwirth, Piotr Jurkiewicz, Martin Hof
Publikováno v:
Open Biology, Vol 14, Iss 9 (2024)
Calmodulin (CaM) is a ubiquitous calcium-sensitive messenger in eukaryotic cells. It was previously shown that CaM possesses an affinity for diverse lipid moieties, including those found on CaM-binding proteins. These facts, together with our observa
Externí odkaz:
https://doaj.org/article/948ba78addc24b15927c4da2d9483558
Autor:
Rahul V. Nene, Melodie A. Santodomingo, Bruce Balog, Hector Martinez, Elias Murillo, Christian A. Tomaszewski, Andrew LaFree
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Objective The treatment of outpatient COVID‐19 patients at high risk of disease progression has been challenging, as both the virus and available therapeutics change. Here, we sought to evaluate the effect of vaccination status on the use
Externí odkaz:
https://doaj.org/article/7d10139d65114bc9bf27cf3d32aa8c6a
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/21cc0234b20844dd8850be74f113a863
Autor:
Matthew D. Smith, Xitiz Chamling, Alexander J. Gill, Hector Martinez, Weifeng Li, Kathryn C. Fitzgerald, Elias S. Sotirchos, Dorota Moroziewicz, Lauren Bauer, Daniel Paull, Marjan Gharagozloo, Pavan Bhargava, Donald J. Zack, Valentina Fossati, Peter A. Calabresi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Astrocytes are instrumental in maintaining central nervous system (CNS) homeostasis and responding to injury. A major limitation of studying neurodegenerative diseases like multiple sclerosis (MS) is lack of human pathological specimens obtained duri
Externí odkaz:
https://doaj.org/article/5803ad7471a74cfb84d0c6510afbb242
Autor:
Joni Vuorio, Jana Škerlová, Milan Fábry, Václav Veverka, Ilpo Vattulainen, Pavlína Řezáčová, Hector Martinez-Seara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract While DNA encodes protein structure, glycans provide a complementary layer of information to protein function. As a prime example of the significance of glycans, the ability of the cell surface receptor CD44 to bind its ligand, hyaluronan, i
Externí odkaz:
https://doaj.org/article/990ff85791054a3e937ff2ae25de0092
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 1, p e1009678 (2022)
Sugars are crucial components in biosystems and industrial applications. In aqueous environments, the natural state of short saccharides or charged glycosaminoglycans is floating and wiggling in solution. Therefore, tools to characterize their struct
Externí odkaz:
https://doaj.org/article/bf6f22c832d94721b3166c1f7c64ac17
Autor:
Francesca Vittoria Sbrana, Riccardo Pinos, Federica Barbaglio, Davide Ribezzi, Fiorella Scagnoli, Lydia Scarfò, Itedale Namro Redwan, Hector Martinez, Silvia Farè, Paolo Ghia, Cristina Scielzo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chronic Lymphocytic Leukemia (CLL) represents the most common leukemia in the western world and remains incurable. Leukemic cells organize and interact in the lymphoid tissues, however what actually occurs in these sites has not been fully elucidated
Externí odkaz:
https://doaj.org/article/71214914a56943d29e9a5805b1f4366d