Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hector M. Picon"'
Autor:
Julia I. Medina, Linette Castillo-Pichardo, Maria Del Mar Maldonado, Ailed Cruz-Collazo, Suranganie Dharmawardhane, Cornelis P. Vlaar, Jean F. Ruiz-Calderon, Eliud Hernandez-O'Farrill, Luis D. Borrero-Garcia, Jorge Duconge, Marvin J Bayro, Irmaris Lopez, Hector M. Picon
Publikováno v:
Mol Cancer Ther
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer, with a high predisposition for locally invasive and metastatic cancer. With the objective to reduce cancer metastasis, we developed small molecule inhibitors to target the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8a786a81c08334bd6c435b9965a5b0
https://europepmc.org/articles/PMC8643341/
https://europepmc.org/articles/PMC8643341/
Autor:
Zhongqi Ge, Ignacio I. Wistuba, Emily Powell, Timothy P. Heffernan, William Fraser Symmans, Sabrina Jeter-Jones, Christopher E. Schlosberg, Stacy L. Moulder, Michael Peoples, John R. Edwards, Fei Yang, Christopher A. Bristow, Hector M. Picon, Jiansu Shao, Kenneth L. Scott, Helen Piwnica-Worms, Yun Wu, Han Liang, Caitlin L. Grzeskowiak, Frederick S. Robinson
Publikováno v:
npj Breast Cancer, Vol 4, Iss 1, Pp 1-12 (2018)
NPJ Breast Cancer
NPJ Breast Cancer
Tumor cells disseminate early in tumor development making metastasis-prevention strategies difficult. Identifying proteins that promote the outgrowth of disseminated tumor cells may provide opportunities for novel therapeutic strategies. Despite mult
Abstract 623: Investigating potential off-target effects of the dual Rac and Cdc42 inhibitor MBQ-167
Publikováno v:
Cancer Research. 80:623-623
Metastasis is a major cause of death in epithelial cancers, largely because of a lack of effective treatments. The metastatic inhibitor MBQ-167 was developed to target the Rho GTPases Rac and Cdc42, which promote cell cycle progression, proliferation
Autor:
Fraser Symmans, Ignacio I. Wistuba, John R. Edwards, Jiansu Shao, Sabrina Jeter-Jones, Timothy P. Heffernan, Christopher A. Bristow, Stacy L. Moulder, Helen Piwnica-Worms, Zhongqi Ge, Yun Wu, Han Liang, Kenneth L. Scott, Hector M. Picon, Fei Yang, Christopher E. Schlosberg, Frederick S. Robinson, Caitlin L. Grzeskowiak, Michael Peoples, Emily Powell
Publikováno v:
Cancer Research. 78:5172-5172
Metastases are responsible for the vast majority of deaths due to breast cancer. Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high rates of metastasis and poor prognosis. We are employing patient-der