Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hector M. Picon"'
Autor:
Julia I. Medina, Linette Castillo-Pichardo, Maria Del Mar Maldonado, Ailed Cruz-Collazo, Suranganie Dharmawardhane, Cornelis P. Vlaar, Jean F. Ruiz-Calderon, Eliud Hernandez-O'Farrill, Luis D. Borrero-Garcia, Jorge Duconge, Marvin J Bayro, Irmaris Lopez, Hector M. Picon
Publikováno v:
Mol Cancer Ther
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer, with a high predisposition for locally invasive and metastatic cancer. With the objective to reduce cancer metastasis, we developed small molecule inhibitors to target the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8a786a81c08334bd6c435b9965a5b0
https://europepmc.org/articles/PMC8643341/
https://europepmc.org/articles/PMC8643341/
Autor:
Zhongqi Ge, Ignacio I. Wistuba, Emily Powell, Timothy P. Heffernan, William Fraser Symmans, Sabrina Jeter-Jones, Christopher E. Schlosberg, Stacy L. Moulder, Michael Peoples, John R. Edwards, Fei Yang, Christopher A. Bristow, Hector M. Picon, Jiansu Shao, Kenneth L. Scott, Helen Piwnica-Worms, Yun Wu, Han Liang, Caitlin L. Grzeskowiak, Frederick S. Robinson
Publikováno v:
npj Breast Cancer, Vol 4, Iss 1, Pp 1-12 (2018)
NPJ Breast Cancer
NPJ Breast Cancer
Tumor cells disseminate early in tumor development making metastasis-prevention strategies difficult. Identifying proteins that promote the outgrowth of disseminated tumor cells may provide opportunities for novel therapeutic strategies. Despite mult
Abstract 623: Investigating potential off-target effects of the dual Rac and Cdc42 inhibitor MBQ-167
Publikováno v:
Cancer Research. 80:623-623
Metastasis is a major cause of death in epithelial cancers, largely because of a lack of effective treatments. The metastatic inhibitor MBQ-167 was developed to target the Rho GTPases Rac and Cdc42, which promote cell cycle progression, proliferation
Autor:
Fraser Symmans, Ignacio I. Wistuba, John R. Edwards, Jiansu Shao, Sabrina Jeter-Jones, Timothy P. Heffernan, Christopher A. Bristow, Stacy L. Moulder, Helen Piwnica-Worms, Zhongqi Ge, Yun Wu, Han Liang, Kenneth L. Scott, Hector M. Picon, Fei Yang, Christopher E. Schlosberg, Frederick S. Robinson, Caitlin L. Grzeskowiak, Michael Peoples, Emily Powell
Publikováno v:
Cancer Research. 78:5172-5172
Metastases are responsible for the vast majority of deaths due to breast cancer. Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high rates of metastasis and poor prognosis. We are employing patient-der
Autor:
Powell, Emily, Shao, Jiansu, Picon, Hector M., Bristow, Christopher, Ge, Zhongqi, Peoples, Michael, Robinson, Frederick, Jeter-Jones, Sabrina L., Schlosberg, Christopher, Grzeskowiak, Caitlin L., Yang, Fei, Wu, Yun, Wistuba, Ignacio, Moulder, Stacy L., Symmans, William F., Scott, Kenneth L., Edwards, John R., Liang, Han, Heffernan, Timothy P., Piwnica-Worms, Helen
Publikováno v:
NPJ Breast Cancer; 2018, Vol. 4 Issue 1, pN.PAG-N.PAG, 1p