Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hector Hernandez Saucedo"'
Autor:
Dan Mungas, Crystal Shaw, Eleanor Hayes‐Larson, Charles DeCarli, Sarah Tomaszewski Farias, John Olichney, Hector Hernandez Saucedo, Paola Gilsanz, M Maria Glymour, Rachel A Whitmer, Elizabeth Rose Mayeda
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction The Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) study enrolled Asian, Black, Latino, and White adults ages 65+ without prior dementia diagnosis (N = 1709). We evaluated the prevalence of cognitive impairment (mil
Externí odkaz:
https://doaj.org/article/f89ffe000d5d4985819311ad4f2ab9dc
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 6, Iss 1, Pp 78-89 (2016)
Background: Glucose intolerance and apolipoprotein ε4 allele (E4+) are risk factors for Alzheimer's disease (AD). Insulin sensitizers show promise for treating AD, but are less effective in E4+ individuals. Little is known about how the APOE genotyp
Externí odkaz:
https://doaj.org/article/2460bb5f8e3a4f50b3c5f1de622080ba
Autor:
Jaclyn M, Eissman, Logan, Dumitrescu, Emily R, Mahoney, Alexandra N, Smith, Shubhabrata, Mukherjee, Michael L, Lee, Phoebe, Scollard, Seo Eun, Choi, William S, Bush, Corinne D, Engelman, Qiongshi, Lu, David W, Fardo, Emily H, Trittschuh, Jesse, Mez, Catherine C, Kaczorowski, Hector, Hernandez Saucedo, Keith F, Widaman, Rachel F, Buckley, Michael J, Properzi, Elizabeth C, Mormino, Hyun Sik, Yang, Theresa M, Harrison, Trey, Hedden, Kwangsik, Nho, Shea J, Andrews, Douglas, Tommet, Niran, Hadad, R Elizabeth, Sanders, Douglas M, Ruderfer, Katherine A, Gifford, Xiaoyuan, Zhong, Neha S, Raghavan, Badri N, Vardarajan, Margaret A, Pericak-Vance, Lindsay A, Farrer, Li San, Wang, Carlos, Cruchaga, Gerard D, Schellenberg, Nancy J, Cox, Jonathan L, Haines, C Dirk, Keene, Andrew J, Saykin, Eric B, Larson, Reisa A, Sperling, Richard, Mayeux, Michael L, Cuccaro, David A, Bennett, Julie A, Schneider, Paul K, Crane, Angela L, Jefferson, Timothy J, Hohman
Publikováno v:
Brain. 145:2541-2554
Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the presence of Alzheimer’s disease neuropathology at autopsy. Studying individuals who are resilient to the cognitive consequences of Alzheimer’s disease neu
Autor:
Sarah E Tomaszewski Farias, Charles DeCarli, Rachel A. Whitmer, John M Olichney, Paola Gilsanz, Dan M Mungas, M. Maria Glymour, Nihal Bhulani, Elizabeth-Rose Mayeda, Hector Hernandez Saucedo, Sunita Miles
Publikováno v:
J Gerontol B Psychol Sci Soc Sci
Objectives Understanding racial/ethnic disparities in late-life cognitive health is a public health imperative. We used baseline data from the Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) study to examine how age, education, gender, an
Autor:
Hyun-Sik Yang, Jesse Mez, Lindsay A. Farrer, Corinne D. Engelman, Emily H. Trittschuh, Paul K. Crane, Francis E. Cambronero, C. Dirk Keene, A Study Team, Timothy J. Hohman, Elizabeth Mormina, William S. Bush, Carlos Cruchaga, David W. Fardo, Nancy J. Cox, Keith F. Widaman, Angela L. Jefferson, R. Elizabeth Sanders, Emily R. Mahoney, Rachel F. Buckley, Doug Tommet, David A. Bennett, Trey Hedden, Katherine A. Gifford, Michael L. Lee, Badri N. Vardarajan, Julie A. Schneider, Logan Dumitrescu, Annah M. Moore, Douglas M. Ruderfer, Shea J. Andrews, Catherine C. Kaczorowski, Tessa Harrison, Andrew J. Saykin, Gerard D. Schellenberg, Xiaoyuan Zhong, Richard Mayeux, Shubhabrata Mukherjee, Niran Hadad, Li-San Wang, Margaret A. Pericak-Vance, Micheal Properzi, Eric B. Larson, Neha S. Raghavan, Qiongshi Lu, Kwangsik Nho, Hector Hernandez Saucedo, Jonathan L. Haines, Reisa A. Sperling
Approximately 30% of older adults exhibit the neuropathologic features of Alzheimer’s disease (AD) without signs of cognitive impairment. Yet, little is known about the genetic factors that allow these potentially resilient individuals to remain co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247b080f494da0d6f03aabdf517200f3
https://doi.org/10.1101/2020.02.19.954651
https://doi.org/10.1101/2020.02.19.954651
Autor:
Shubhabrata Mukherjee, David W. Fardo, Jonathan L. Haines, Timothy J. Hohman, Trey Hedden, Xiaoyuan Zhong, Michael L. Lee, Gerard D. Schellenberg, Reisa A. Sperling, Paul K. Crane, Nancy J. Cox, Niran Hadad, Neha S. Raghavan, Hyun-Sik Yang, Qiongshi Lu, Badri N. Vardarajan, Margaret A. Pericak-Vance, Shea J. Andrews, Keith F. Widaman, Kwangsik Nho, Corinne D. Engelman, C. Dirk Keene, Julie A. Schneider, Tessa Harrison, Andrew J. Saykin, Eric B. Larson, Angela L. Jefferson, Emily R. Mahoney, David A. Bennett, R. Elizabeth Sanders, Elizabeth C. Mormino, Annah M. Moore, Logan Dumitrescu, Hector Hernandez Saucedo, Michael J. Properzi, Doug Tommet, Rachel F. Buckley, Francis E. Cambronero, Richard Mayeux, William S. Bush, Douglas M. Ruderfer, Catherine C. Kaczorowski, Emily H. Trittschuh, Carlos Cruchaga, Li-San Wang, Katherine A. Gifford, Lindsay A. Farrer, Jesse Mez
Publikováno v:
Brain
Why are some individuals able to tolerate severe Alzheimer’s disease pathology without experiencing dementia? Dumitrescu et al. perform a large genome-wide analysis of resilience to Alzheimer’s disease and highlight several biological pathways th
Autor:
Charles P. Quesenberry, Elizabeth Rose Mayeda, Sunita Miles, Dan M Mungas, Rachel A. Whitmer, Ashley E. Richards, Paola Gilsanz, Hector Hernandez Saucedo, M. Maria Glymour, Charlie S. DeCarli
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Nihal Bhulani, Rachel A. Whitmer, Charlie S. DeCarli, Dan M Mungas, Paola Gilsanz, M. Maria Glymour, Hector Hernandez Saucedo, Sunita Miles
Publikováno v:
Alzheimer's & Dementia. 15:P835-P836
Autor:
Charles DeCarli, Rachel A. Whitmer, Elizabeth Rose Mayeda, Paola Gilsanz, Sunita Miles, Hector Hernandez Saucedo, M. Maria Glymour, Chloe W. Eng, Dan M Mungas, Charles P. Quesenberry
Publikováno v:
Alzheimer's & Dementia. 15:P475-P475
Autor:
Consuelo H. Wilkins, James B. Leverenz, Hector Hernandez-Saucedo, Angela Hansen, Laura D. Baker, Selena Corbett, Jeannine S. Skinner, Suzanne Craft, Amy Morgan, Matthew Arbuckle
Publikováno v:
Journal of Gerontology & Geriatric Research.
Background: Glucose and insulin are important moderators of cognitive function. African Americans have poorer glycemic control across the glycemic spectrum and are at increased risk for type 2 diabetes and poor cognitive health. It is unclear which g