Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hector Biliran"'
Autor:
Xin Yao, Tri Pham, Brandi Temple, Selena Gray, Cornita Cannon, Renwei Chen, Asim B Abdel-Mageed, Hector Biliran
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163228 (2016)
The mitochondrial Bcl-2 inhibitor of transcription 1 (Bit1) protein is part of an anoikis-regulating pathway that is selectively dependent on integrins. We previously demonstrated that the caspase-independent apoptotic effector Bit1 exerts tumor supp
Externí odkaz:
https://doaj.org/article/a0c94ca466524acb8607627464f6e080
Autor:
Xin Yao, Scott Jennings, Shubha Kale Ireland, Tri Pham, Brandi Temple, Mya Davis, Renwei Chen, Ian Davenport, Hector Biliran
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101564 (2014)
The mitochondrial Bit1 (Bcl-2 inhibitor of transcription 1) protein is a part of an apoptotic pathway that is uniquely regulated by integrin-mediated attachment. As an anoikis effector, Bit1 is released into the cytoplasm following loss of cell attac
Externí odkaz:
https://doaj.org/article/b3bef84e93a54d7aafda3d0eb5f14f6d
Autor:
Priya Prakash Karmali, Chris Brunquell, Hau Tram, Shubha Kale Ireland, Erkki Ruoslahti, Hector Biliran
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23840 (2011)
Resistance to anoikis, which is defined as apoptosis induced by loss of integrin-mediated cell attachment to the extracellular matrix, is a determinant of tumor progression and metastasis. We have previously identified the mitochondrial Bit1 (Bcl-2 i
Externí odkaz:
https://doaj.org/article/698575403d5346918ea65b83d5607b31
Autor:
Erkki Ruoslahti, Renwei Chen, Shubha Kale Ireland, Scott Jennings, Hector Biliran, Chris Brunquell
TLE1 is a Groucho-related transcriptional repressor protein that exerts survival and antiapoptotic function in several cellular systems and has been implicated in the pathogenesis of cancer. In the present study, we found that TLE1 is a regulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5933058a06a7c30344a6bf0aa0357ec4
https://doi.org/10.1158/1541-7786.c.6541515
https://doi.org/10.1158/1541-7786.c.6541515
Autor:
Erkki Ruoslahti, Renwei Chen, Shubha Kale Ireland, Scott Jennings, Hector Biliran, Chris Brunquell
PDF file - 817K, S1. Expression of exogenous GFP-TLE1 in stable MCF10A derived GFP-TLE1 and control overexpressing cells was confirmed by SDSPAGE and immunoblotting using the total cell lysates derived from control and TLE1 overexpressing pools again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264337429375e0df1ffb77cd9d4ddf0a
https://doi.org/10.1158/1541-7786.22516863
https://doi.org/10.1158/1541-7786.22516863
Autor:
Erkki Ruoslahti, Renwei Chen, Shubha Kale Ireland, Scott Jennings, Hector Biliran, Chris Brunquell
PDF file - 392K, MCF10-CA1a and HOP-92 cells were treated with iRGD-CDD or etoposide (20uM).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f66ab300d24a32a64149523d6da6b82
https://doi.org/10.1158/1541-7786.22516872
https://doi.org/10.1158/1541-7786.22516872
Autor:
Harris E. McFerrin, Hector Biliran, Harish Ratnayaka, Syed Muniruzzaman, Shubha Kale Ireland, Mary C. Carmichael
Publikováno v:
ICERI Proceedings.
Autor:
Selena Gray, Shubha Kale Ireland, An Nguyen, Stephen Do, Hector Biliran, Renwei Chen, Asim B. Abdel-Mageed, Xin Yao, Mychael Delgardo, Tri Pham
Publikováno v:
Biochemical and Biophysical Research Communications. 495:1240-1248
The mitochondrial Bit1 protein exerts tumor-suppressive function in NSCLC through induction of anoikis and inhibition of EMT. Having this dual tumor suppressive effect, its downregulation in the established human lung adenocarcinoma A549 cell line re
Autor:
Camry Hardy, Ahamed Hossain, Cornita Cannon, Shubha Kale Ireland, Asim B. Abdel-Mageed, Brandi Temple, Xin Yao, Renwei Chen, Hector Biliran, Kamari Fletcher, Selena Gray, Tri Pham
Publikováno v:
Oncotarget
// Xin Yao 1 , Tri Pham 1 , Brandi Temple 1 , Selena Gray 1 , Cornita Cannon 1 , Camry Hardy 1 , Kamari Fletcher 1 , Shubha Kale Ireland 1 , Ahamed Hossain 1 , Renwei Chen 2 , Asim B. Abdel-Mageed 3 and Hector Biliran 1 1 Department of Biological and