Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Hector Barajas‑Martinez"'
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) were initially recommended as oral anti-diabetic drugs to treat type 2 diabetes (T2D), by inhibiting SGLT2 in proximal tubule and reduce renal reabsorption of sodium and glucose. While
Externí odkaz:
https://doaj.org/article/6e17f767eae44338b0347bb08197d2ba
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/31dcf02c8a6c421cba79991189c1c3df
Autor:
José M Di Diego, Hector Barajas-Martinez, Robert Cox, Victoria M Robinson, Joseph Jung, Mohamed Fouda, Bence Patocskai, Mena Abdelsayed, Peter C Ruben, Charles Antzelevitch
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0281977 (2023)
BackgroundBrugada (BrS) and early repolarization syndromes (ERS), the so-called J wave syndromes (JWS), are associated with life-threatening ventricular arrhythmias. Pharmacologic approaches to therapy are currently limited. In this study, we examine
Externí odkaz:
https://doaj.org/article/d3a06d40c7504261885014a5c3d40279
Autor:
Yan Huang, Hua-Sheng Ding, Tao Song, Yu-Ting Chen, Teng Wang, Yan-Hong Tang, Hector Barajas-Martinez, Cong-Xin Huang, Dan Hu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Introduction: Myocardial infarction (MI) triggers structural and electrical remodeling. CC chemokine receptor 9 (CCR9) mediates chemotaxis of inflammatory cells in MI. In our previous study, CCR9 knockout has been found to improve structural remodeli
Externí odkaz:
https://doaj.org/article/9b4a6ad32a614b9a9bb5f85c151713bd
Autor:
Ganxiao Chen, Xun Li, Zuojiong Gong, Hao Xia, Yao Wang, Xuefen Wang, Yan Huang, Hector Barajas-Martinez, Dan Hu
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250815 (2021)
BackgroundCOVID-19 is a respiratory infectious disease caused by SARS-CoV-2, and cardiovascular damage is commonly observed in affected patients. We sought to investigate the effect of SARS-CoV-2 infection on cardiac injury and hypertension during th
Externí odkaz:
https://doaj.org/article/5cae51a652964177b2e25a5ff29f15b5
Autor:
Dan, Ye, Wei, Zhou, Samantha K, Hamrick, David J, Tester, C S John, Kim, Hector, Barajas-Martinez, Dan, Hu, John R, Giudicessi, Charles, Antzelevitch, Michael J, Ackerman
Publikováno v:
Circulation. Genomic and precision medicine. 15(5)
The transient outward current (Ito) that mediates early (phase 1) repolarization is conducted by theKCND3-V392I was identified in an 18-year-old male with J wave syndrome/early repolarization syndrome, and a history of cardiac arrest including ventri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f5fadfc6283d9541c9ec09009a5958b
https://pubmed.ncbi.nlm.nih.gov/35861988
https://pubmed.ncbi.nlm.nih.gov/35861988
Autor:
Dan Hu, Dong Hu, Liwen Liu, Daniel Barr, Yang Liu, Norma Balderrabano-Saucedo, Bo Wang, Feng Zhu, Yumei Xue, Shulin Wu, BaoLiang Song, Heather McManus, Katherine Murphy, Katherine Loes, Arnon Adler, Lorenzo Monserrat, Charles Antzelevitch, Michael H. Gollob, Perry M. Elliott, Hector Barajas-Martinez
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Background: Although 21 causative mutations have been associated with PRKAG2 syndrome, our understanding of the syndrome remains incomplete. The aim of this project is to further investigate its unique genetic background, clinical manifestations, and
Externí odkaz:
https://doaj.org/article/261fdad085bf4de79b25dd66139363da
Autor:
José M Di Diego, Bence Patocskai, Hector Barajas-Martinez, Virág Borbáth, Michael J Ackerman, Alexander Burashnikov, Jérôme Clatot, Gui-Rong Li, Victoria M Robinson, Dan Hu, Charles Antzelevitch
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242747 (2020)
BackgroundJ wave syndromes (JWS), including Brugada (BrS) and early repolarization syndromes (ERS), are associated with increased risk for life-threatening ventricular arrhythmias. Pharmacologic approaches to therapy are currently very limited. Here,
Externí odkaz:
https://doaj.org/article/3cb25873eea6466eadaeb09bad7cd916
Autor:
Hector Barajas-Martinez, Maya Smith, Dan Hu, Robert J. Goodrow, Colleen Puleo, Can Hasdemir, Charles Antzelevitch, Ryan Pfeiffer, Jacqueline A. Treat, Jonathan M. Cordeiro
Publikováno v:
Stem Cells International, Vol 2020 (2020)
Background. We report an inherited cardiac arrhythmia syndrome consisting of Brugada and Early Repolarization Syndrome associated with variants in SCN9A, PXDNL, and FKBP1B. The proband inherited the 3 mutations and exhibited palpitations and arrhythm
Externí odkaz:
https://doaj.org/article/680c9642bcdf4b898046c0ee9402fb20
Autor:
Yanhong Chen, Hector Barajas-Martinez, Dongxiao Zhu, Xihui Wang, Chonghao Chen, Ruijuan Zhuang, Jingjing Shi, Xueming Wu, Yijia Tao, Weidong Jin, Xiaoyan Wang, Dan Hu
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background Hypertrophic cardiomyopathy (HCM) patients with early repolarization (ER) pattern are at higher risk of ventricular arrhythmia, yet the genetic background of this situation has not been well investigated. Here we report novel trig
Externí odkaz:
https://doaj.org/article/530c1953d13146ff890dc7c2fba9d86a