Terpenes from Cannabis sativa Induce Antinociception in Mouse Chronic Neuropathic Pain via Activation of Spinal Cord Adenosine A 2A Receptors.

Autor: Schwarz AM; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Keresztes A; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Bui T; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Hecksel RJ; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Peña A; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Lent B; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Gao ZG; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD USA., Gamez-Rivera M; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Seekins CA; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Chou K; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Appel TL; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Jacobson KA; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda MD USA., Al-Obeidi FA; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA., Streicher JM; Department of Pharmacology, College of Medicine, University of Arizona, Tucson AZ USA.; Comprehensive Pain and Addiction Center, University of Arizona, Tucson AZ USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 29. Date of Electronic Publication: 2023 Mar 29.