Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A

Autor: Erzinger, Melanie M., Bovet, Cédric, Hecht, Katrin M., Senger, Sabine, Winiker, Pascale, Sobotzki, Nadine, Cristea, Simona, Beerenwinkel, Niko, Shay, Jerry W., Marra, Giancarlo, Wollscheid, Bernd, Sturla, Shana J.

The chemoprotective properties of sulforaphane (SF), derived from cruciferous vegetables, are widely acknowledged to arise from its potent induction of xenobiotic-metabolizing and antioxidant enzymes. However, much less is known about the impact of S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72705de51f3ffb459855cf668b1e9918

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A.

Autor: Erzinger MM; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Bovet C; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Hecht KM; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Senger S; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Winiker P; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland., Sobotzki N; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland., Cristea S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, Basel, Switzerland., Beerenwinkel N; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, Basel, Switzerland., Shay JW; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America., Marra G; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland., Wollscheid B; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; BioMedical Proteomics Platform (BMPP), ETH Zurich, Zurich, Switzerland., Sturla SJ; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.

Publikováno v: PloS one [PLoS One] 2016 Mar 07; Vol. 11 (3), pp. e0150219. Date of Electronic Publication: 2016 Mar 07 (Print Publication: 2016).