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pro vyhledávání: '"Hebah Falatah"'
Autor:
Quezia Lacerda, Hebah Falatah, Ji-Bin Liu, Corinne E. Wessner, Brian Oeffinger, Ankit Rochani, Dennis B. Leeper, Flemming Forsberg, Joseph M. Curry, Gagan Kaushal, Scott W. Keith, Patrick O’Kane, Margaret A. Wheatley, John R. Eisenbrey
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1302 (2023)
Tumor hypoxia (oxygen deficiency) is a major contributor to radiotherapy resistance. Ultrasound-sensitive microbubbles containing oxygen have been explored as a mechanism for overcoming tumor hypoxia locally prior to radiotherapy. Previously, our gro
Externí odkaz:
https://doaj.org/article/1a19f6f3948d4cdd96820563b7ebdc10
Autor:
Quezia, Lacerda, Ankit, Rochani, Brian, Oeffinger, Ji-Bin, Liu, Corinne E, Wessner, Aylin, Tahmasebi, Hebah, Falatah, Philip, Lee, Dennis B, Leeper, Flemming, Forsberg, Joseph, Curry, Scott W, Keith, Patrick, O'Kane, Gagan, Kaushal, Margaret A, Wheatley, John R, Eisenbrey
Publikováno v:
Int J Pharm
Prior work has shown that microbubble-assisted delivery of oxygen improves tumor oxygenation and radiosensitivity, albeit over a limited duration. Lonidamine (LND) has been investigated because of its ability to stimulate glycolysis, lactate producti